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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Targeted Oncology
Published in: Targeted Oncology 3/2010

01-09-2010 | Review

Molecular markers in gliomas: impact for the clinician

Authors: Silvia Hofer, Andrew B. Lassman

Published in: Targeted Oncology | Issue 3/2010

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Abstract

Over the last decade, understanding of glioma on a molecular level has greatly expanded. However, optimal incorporation of molecular markers into clinical care is controversial. We briefly review the potential utility of molecular stratification in refining histologic diagnosis, prognosis, and treatment decisions, focussing on 1p/19q co-deletion, MGMT promoter methylation, EGFR mutations, and IDH mutation. The most recently discovered IDH mutation is a striking example of a rapid implementation of a molecular marker for prognostication into common clinical use.
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Metadata
Title
Molecular markers in gliomas: impact for the clinician
Authors
Silvia Hofer
Andrew B. Lassman
Publication date
01-09-2010
Publisher
Springer-Verlag
Published in
Targeted Oncology / Issue 3/2010
Print ISSN: 1776-2596
Electronic ISSN: 1776-260X
DOI
https://doi.org/10.1007/s11523-010-0157-2

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