Skip to main content
Top
Published in: HSS Journal ® 3/2013

Open Access 01-10-2013 | Review Article

Imaging Metal-on-Metal Hip Replacements: the Norwich Experience

Authors: Marianna S. Thomas, FRCR, James A. Wimhurst, FRCS(Orth), John F. Nolan, FRCS(Orth), Andoni P. Toms, FRCR, PhD

Published in: HSS Journal ® | Issue 3/2013

Login to get access

Abstract

Background

Adverse reaction to metal debris is a relatively recently described and often a silent complication of metal-on-metal (MOM) total hip replacements (THR). The Norfolk & Norwich University Hospital has been performing metal artefact reduction (MARS) MRI for 8 years in a variety of different types of MOM THR.

Questions/purposes

The aims of this review are to describe the experience of using MARS MRI in Norwich and to compare our experience with that published by other groups.

Methods

A MEDLINE keyword search was performed for studies including MRI in MOM THR. Relevant publications were reviewed and compared with published data from the Norfolk & Norwich University Hospital. The similarities and differences between these data were compared and possible explanations for these discussed.

Results

MARS MRI appears to be the most useful tool for diagnosing, staging and monitoring adverse reactions to metal debris (ARMD). There appears to be no clinically useful association between clinical and serological markers of disease and the severity of MR findings. Although severe early ARMD is associated with significant morbidity, mild disease is often stable for years. If patients with normal initial MR examinations develop ARMD, this usually occurs 7 years. A 1-year interval between MRI examinations is reasonable in asymptomatic patients.

Conclusions

There is a general international consensus that ARMD is prevalent in symptomatic and asymptomatic patients with MOM THR and that while appearances vary with the type of prosthesis, there are characteristic features that make MARS MRI essential for diagnosis, staging and surveillance of the disease.
Appendix
Available only for authorised users
Literature
1.
go back to reference 9th Annual Report. Surgical data to 31 December 2011: National Joint Registry for England and Wales; 2012. 9th Annual Report. Surgical data to 31 December 2011: National Joint Registry for England and Wales; 2012.
2.
go back to reference Amstutz HC, Campbell P, McKellop H, et al. Metal on metal total hip replacement workshop consensus document. Clin Orthop Relat Res. Aug 1996(329 Suppl):S297–303. Amstutz HC, Campbell P, McKellop H, et al. Metal on metal total hip replacement workshop consensus document. Clin Orthop Relat Res. Aug 1996(329 Suppl):S297–303.
3.
go back to reference Amstutz HC, Grigoris P. Metal on metal bearings in hip arthroplasty. Clin Orthop Relat Res. Aug 1996(329 Suppl):S11–34. Amstutz HC, Grigoris P. Metal on metal bearings in hip arthroplasty. Clin Orthop Relat Res. Aug 1996(329 Suppl):S11–34.
4.
go back to reference Anderson H, Toms AP, Cahir JG, Goodwin RW, Wimhurst J, Nolan JF. Grading the severity of soft tissue changes associated with metal-on-metal hip replacements: reliability of an MR grading system. Skeletal Radiol. 2011;40(3):303–7.PubMedCrossRef Anderson H, Toms AP, Cahir JG, Goodwin RW, Wimhurst J, Nolan JF. Grading the severity of soft tissue changes associated with metal-on-metal hip replacements: reliability of an MR grading system. Skeletal Radiol. 2011;40(3):303–7.PubMedCrossRef
5.
go back to reference August AC, Aldam CH, Pynsent PB. The McKee–Farrar hip arthroplasty. A long-term study. J Bone Joint Surg Br. 1986;68(4):520–7.PubMed August AC, Aldam CH, Pynsent PB. The McKee–Farrar hip arthroplasty. A long-term study. J Bone Joint Surg Br. 1986;68(4):520–7.PubMed
6.
go back to reference Bosker BH, Ettema HB, Boomsma MF, Kollen BJ, Maas M, Verheyen CC. High incidence of pseudotumour formation after large-diameter metal-on-metal total hip replacement: a prospective cohort study. J Bone Joint Surg Br. 2012;94(6):755–61.PubMed Bosker BH, Ettema HB, Boomsma MF, Kollen BJ, Maas M, Verheyen CC. High incidence of pseudotumour formation after large-diameter metal-on-metal total hip replacement: a prospective cohort study. J Bone Joint Surg Br. 2012;94(6):755–61.PubMed
7.
go back to reference Brittain HA. Architectural principles in arthrodesis. Edinburgh: E&S Livingstone Ltd; 1952. Brittain HA. Architectural principles in arthrodesis. Edinburgh: E&S Livingstone Ltd; 1952.
8.
go back to reference Cha JG, Hong HS, Park JS, Paik SH, Lee HK. Practical application of iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) imaging in minimizing metallic artifacts. Korean J Radiol. 2012;13(3):332–41.PubMedCrossRef Cha JG, Hong HS, Park JS, Paik SH, Lee HK. Practical application of iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) imaging in minimizing metallic artifacts. Korean J Radiol. 2012;13(3):332–41.PubMedCrossRef
9.
go back to reference Chang EY, McAnally JL, Van Horne JR, et al. Metal-on-Metal Total Hip Arthroplasty: Do Symptoms Correlate with MR Imaging Findings? Radiology. 2012;265(3):848–57.PubMedCrossRef Chang EY, McAnally JL, Van Horne JR, et al. Metal-on-Metal Total Hip Arthroplasty: Do Symptoms Correlate with MR Imaging Findings? Radiology. 2012;265(3):848–57.PubMedCrossRef
10.
go back to reference Delaunay C, Petit I, Learmonth ID, Oger P, Vendittoli PA. Metal-on-metal bearings total hip arthroplasty: the cobalt and chromium ions release concern. Orthop Traumatol Surg Res. 2010;96(8):894–904.PubMedCrossRef Delaunay C, Petit I, Learmonth ID, Oger P, Vendittoli PA. Metal-on-metal bearings total hip arthroplasty: the cobalt and chromium ions release concern. Orthop Traumatol Surg Res. 2010;96(8):894–904.PubMedCrossRef
11.
go back to reference Early Development of Total Hip Replacement. Vol 29. Wellcome Trust Centre for the History of Medicine; 2007. Early Development of Total Hip Replacement. Vol 29. Wellcome Trust Centre for the History of Medicine; 2007.
12.
go back to reference Ebreo D, Bell PJ, Arshad H, Donell ST, Toms A, Nolan JF. Serial magnetic resonance imaging of metal-on-metal total hip replacements: follow-up of a cohort of 28 mm Ultima TPS THRs. Bone Joint J. 2013;95-B(8):1035–9. doi:10.1302/0301-620X.95B8.31377. Ebreo D, Bell PJ, Arshad H, Donell ST, Toms A, Nolan JF. Serial magnetic resonance imaging of metal-on-metal total hip replacements: follow-up of a cohort of 28 mm Ultima TPS THRs. Bone Joint J. 2013;95-B(8):1035–9. doi:10.​1302/​0301-620X.​95B8.​31377.
13.
go back to reference Fang CS, Harvie P, Gibbons CL, Whitwell D, Athanasou NA, Ostlere S. The imaging spectrum of peri-articular inflammatory masses following metal-on-metal hip resurfacing. Skeletal Radiol. 2008;37(8):715–22.PubMedCrossRef Fang CS, Harvie P, Gibbons CL, Whitwell D, Athanasou NA, Ostlere S. The imaging spectrum of peri-articular inflammatory masses following metal-on-metal hip resurfacing. Skeletal Radiol. 2008;37(8):715–22.PubMedCrossRef
14.
go back to reference Gruber FW, Bock A, Trattnig S, Lintner F, Ritschl P. Cystic lesion of the groin due to metallosis: a rare long-term complication of metal-on-metal total hip arthroplasty. J Arthroplasty. 2007;22(6):923–7.PubMedCrossRef Gruber FW, Bock A, Trattnig S, Lintner F, Ritschl P. Cystic lesion of the groin due to metallosis: a rare long-term complication of metal-on-metal total hip arthroplasty. J Arthroplasty. 2007;22(6):923–7.PubMedCrossRef
15.
go back to reference Hargreaves BA, Worters PW, Pauly KB, Pauly JM, Koch KM, Gold GE. Metal-induced artifacts in MRI. AJR Am J Roentgenol. 2011;197(3):547–55.PubMedCrossRef Hargreaves BA, Worters PW, Pauly KB, Pauly JM, Koch KM, Gold GE. Metal-induced artifacts in MRI. AJR Am J Roentgenol. 2011;197(3):547–55.PubMedCrossRef
16.
go back to reference Hart AJ, Sabah S, Henckel J, et al. The painful metal-on-metal hip resurfacing. J Bone Joint Surg Br. 2009;91(6):738–44.PubMed Hart AJ, Sabah S, Henckel J, et al. The painful metal-on-metal hip resurfacing. J Bone Joint Surg Br. 2009;91(6):738–44.PubMed
17.
go back to reference Hart AJ, Satchithananda K, Liddle AD, et al. Pseudotumors in association with well-functioning metal-on-metal hip prostheses: a case–control study using three-dimensional computed tomography and magnetic resonance imaging. J Bone Joint Surg Am. 2012;94(4):317–25.PubMedCrossRef Hart AJ, Satchithananda K, Liddle AD, et al. Pseudotumors in association with well-functioning metal-on-metal hip prostheses: a case–control study using three-dimensional computed tomography and magnetic resonance imaging. J Bone Joint Surg Am. 2012;94(4):317–25.PubMedCrossRef
18.
go back to reference Hasegawa M, Yoshida K, Wakabayashi H, Sudo A. Prevalence of adverse reactions to metal debris following metal-on-metal THA. Orthopedics. 2013;36(5):e606–12.PubMedCrossRef Hasegawa M, Yoshida K, Wakabayashi H, Sudo A. Prevalence of adverse reactions to metal debris following metal-on-metal THA. Orthopedics. 2013;36(5):e606–12.PubMedCrossRef
19.
go back to reference Hauptfleisch J, Pandit H, Grammatopoulos G, Gill HS, Murray DW, Ostlere S. A MRI classification of periprosthetic soft tissue masses (pseudotumours) associated with metal-on-metal resurfacing hip arthroplasty. Skeletal Radiol. 2012;41(2):149–55.PubMedCrossRef Hauptfleisch J, Pandit H, Grammatopoulos G, Gill HS, Murray DW, Ostlere S. A MRI classification of periprosthetic soft tissue masses (pseudotumours) associated with metal-on-metal resurfacing hip arthroplasty. Skeletal Radiol. 2012;41(2):149–55.PubMedCrossRef
20.
go back to reference Hayter CL, Gold SL, Koff MF, et al. MRI findings in painful metal-on-metal hip arthroplasty. AJR Am J Roentgenol. 2012;199(4):884–93.PubMedCrossRef Hayter CL, Gold SL, Koff MF, et al. MRI findings in painful metal-on-metal hip arthroplasty. AJR Am J Roentgenol. 2012;199(4):884–93.PubMedCrossRef
21.
go back to reference Hayter CL, Koff MF, Shah P, Koch KM, Miller TT, Potter HG. MRI after arthroplasty: comparison of MAVRIC and conventional fast spin-echo techniques. AJR Am J Roentgenol. 2011;197(3):W405–11.PubMedCrossRef Hayter CL, Koff MF, Shah P, Koch KM, Miller TT, Potter HG. MRI after arthroplasty: comparison of MAVRIC and conventional fast spin-echo techniques. AJR Am J Roentgenol. 2011;197(3):W405–11.PubMedCrossRef
22.
go back to reference Hayter CL, Potter HG, Su EP. Imaging of metal-on-metal hip resurfacing. Orthop Clin North Am. 2011;42(2):195–205, viii.PubMedCrossRef Hayter CL, Potter HG, Su EP. Imaging of metal-on-metal hip resurfacing. Orthop Clin North Am. 2011;42(2):195–205, viii.PubMedCrossRef
23.
go back to reference Heath JC, Freeman MA, Swanson SA. Carcinogenic properties of wear particles from prostheses made in cobalt-chromium alloy. Lancet. 1971;1(7699):564–6.PubMedCrossRef Heath JC, Freeman MA, Swanson SA. Carcinogenic properties of wear particles from prostheses made in cobalt-chromium alloy. Lancet. 1971;1(7699):564–6.PubMedCrossRef
24.
go back to reference Jacobsson SA, Djerf K, Wahlstrom O. Twenty-year results of McKee–Farrar versus Charnley prosthesis. Clin Orthop Relat Res. 1996(329 Suppl):S60–8. Jacobsson SA, Djerf K, Wahlstrom O. Twenty-year results of McKee–Farrar versus Charnley prosthesis. Clin Orthop Relat Res. 1996(329 Suppl):S60–8.
25.
go back to reference Kwon YM, Ostlere SJ, McLardy-Smith P, Athanasou NA, Gill HS, Murray DW. “Asymptomatic” pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study. J Arthroplasty. 2011;26(4):511–8.PubMedCrossRef Kwon YM, Ostlere SJ, McLardy-Smith P, Athanasou NA, Gill HS, Murray DW. “Asymptomatic” pseudotumors after metal-on-metal hip resurfacing arthroplasty: prevalence and metal ion study. J Arthroplasty. 2011;26(4):511–8.PubMedCrossRef
26.
go back to reference Langton DJ, Jameson SS, Joyce TJ, et al. Accelerating failure rate of the ASR total hip replacement. J Bone Joint Surg Br. 2011;93(8):1011–6.PubMed Langton DJ, Jameson SS, Joyce TJ, et al. Accelerating failure rate of the ASR total hip replacement. J Bone Joint Surg Br. 2011;93(8):1011–6.PubMed
27.
go back to reference Macnair RD, Wynn-Jones H, Wimhurst JA, Toms A, Cahir J. Metal ion levels not sufficient as a screening measure for adverse reactions in metal-on-metal hip arthroplasties. J Arthroplasty. 2013;28(1):78–83.PubMedCrossRef Macnair RD, Wynn-Jones H, Wimhurst JA, Toms A, Cahir J. Metal ion levels not sufficient as a screening measure for adverse reactions in metal-on-metal hip arthroplasties. J Arthroplasty. 2013;28(1):78–83.PubMedCrossRef
28.
go back to reference Malek IA, King A, Sharma H, et al. The sensitivity, specificity and predictive values of raised plasma metal ion levels in the diagnosis of adverse reaction to metal debris in symptomatic patients with a metal-on-metal arthroplasty of the hip. J Bone Joint Surg Br. 2012;94(8):1045–50.PubMed Malek IA, King A, Sharma H, et al. The sensitivity, specificity and predictive values of raised plasma metal ion levels in the diagnosis of adverse reaction to metal debris in symptomatic patients with a metal-on-metal arthroplasty of the hip. J Bone Joint Surg Br. 2012;94(8):1045–50.PubMed
29.
go back to reference Matthies AK, Skinner JA, Osmani H, Henckel J, Hart AJ. Pseudotumors are common in well-positioned low-wearing metal-on-metal hips. Clin Orthop Relat Res. 2012;470(7):1895–906.PubMedCrossRef Matthies AK, Skinner JA, Osmani H, Henckel J, Hart AJ. Pseudotumors are common in well-positioned low-wearing metal-on-metal hips. Clin Orthop Relat Res. 2012;470(7):1895–906.PubMedCrossRef
30.
go back to reference Mistry A, Cahir J, Donell ST, Nolan J, Toms AP. MRI of asymptomatic patients with metal-on-metal and polyethylene-on-metal total hip arthroplasties. Clin Radiol. 2011;66(6):540–5.PubMedCrossRef Mistry A, Cahir J, Donell ST, Nolan J, Toms AP. MRI of asymptomatic patients with metal-on-metal and polyethylene-on-metal total hip arthroplasties. Clin Radiol. 2011;66(6):540–5.PubMedCrossRef
31.
go back to reference Nawabi DH, Gold S, Lyman S, Fields K, Padgett DE, Potter HG. MRI Predicts ALVAL and Tissue Damage in Metal-on-Metal Hip Arthroplasty. Clin Orthop Relat Res. Jan 26 2013 [Epub ahead of print]. Nawabi DH, Gold S, Lyman S, Fields K, Padgett DE, Potter HG. MRI Predicts ALVAL and Tissue Damage in Metal-on-Metal Hip Arthroplasty. Clin Orthop Relat Res. Jan 26 2013 [Epub ahead of print].
32.
go back to reference Nawabi DH, Hayter CL, Su EP, et al. Magnetic resonance imaging findings in symptomatic versus asymptomatic subjects following metal-on-metal hip resurfacing arthroplasty. J Bone Joint Surg Am. 2013;95(10):895–902.PubMedCrossRef Nawabi DH, Hayter CL, Su EP, et al. Magnetic resonance imaging findings in symptomatic versus asymptomatic subjects following metal-on-metal hip resurfacing arthroplasty. J Bone Joint Surg Am. 2013;95(10):895–902.PubMedCrossRef
33.
go back to reference Pandit H, Glyn-Jones S, McLardy-Smith P, et al. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2008;90(7):847–51.PubMed Pandit H, Glyn-Jones S, McLardy-Smith P, et al. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2008;90(7):847–51.PubMed
34.
go back to reference Pfirrmann CW, Notzli HP, Dora C, Hodler J, Zanetti M. Abductor tendons and muscles assessed at MR imaging after total hip arthroplasty in asymptomatic and symptomatic patients. Radiology. 2005;235(3):969–76.PubMedCrossRef Pfirrmann CW, Notzli HP, Dora C, Hodler J, Zanetti M. Abductor tendons and muscles assessed at MR imaging after total hip arthroplasty in asymptomatic and symptomatic patients. Radiology. 2005;235(3):969–76.PubMedCrossRef
35.
go back to reference Potter HG, Montgomery KD, Padgett DE, Salvati EA, Helfet DL. Magnetic resonance imaging of the pelvis. New orthopaedic applications. Clin Orthop Relat Res. 1995(319):223–31.PubMed Potter HG, Montgomery KD, Padgett DE, Salvati EA, Helfet DL. Magnetic resonance imaging of the pelvis. New orthopaedic applications. Clin Orthop Relat Res. 1995(319):223–31.PubMed
36.
go back to reference Potter HG, Nestor BJ, Sofka CM, Ho ST, Peters LE, Salvati EA. Magnetic resonance imaging after total hip arthroplasty: evaluation of periprosthetic soft tissue. J Bone Joint Surg Am. 2004;86-A(9):1947–54.PubMed Potter HG, Nestor BJ, Sofka CM, Ho ST, Peters LE, Salvati EA. Magnetic resonance imaging after total hip arthroplasty: evaluation of periprosthetic soft tissue. J Bone Joint Surg Am. 2004;86-A(9):1947–54.PubMed
37.
go back to reference Medical Device Alert Ref: MDA/2012/036. In: Health Do, ed. All metal-on-metal (MoM) hip replacements. UK: Medicines and Healthcare product Regulatory Agency; 2012. Medical Device Alert Ref: MDA/2012/036. In: Health Do, ed. All metal-on-metal (MoM) hip replacements. UK: Medicines and Healthcare product Regulatory Agency; 2012.
38.
go back to reference Sabah SA, Mitchell AW, Henckel J, Sandison A, Skinner JA, Hart AJ. Magnetic resonance imaging findings in painful metal-on-metal hips: a prospective study. J Arthroplasty. 2011;26(1):71–6.PubMedCrossRef Sabah SA, Mitchell AW, Henckel J, Sandison A, Skinner JA, Hart AJ. Magnetic resonance imaging findings in painful metal-on-metal hips: a prospective study. J Arthroplasty. 2011;26(1):71–6.PubMedCrossRef
39.
go back to reference Streicher RM, Semlitsch M, Schon R, Weber H, Rieker C. Metal-on-metal articulation for artificial hip joints: laboratory study and clinical results. Proc Inst Mech Eng H. 1996;210(3):223–32.PubMed Streicher RM, Semlitsch M, Schon R, Weber H, Rieker C. Metal-on-metal articulation for artificial hip joints: laboratory study and clinical results. Proc Inst Mech Eng H. 1996;210(3):223–32.PubMed
40.
go back to reference Sutter R, Ulbrich EJ, Jellus V, Nittka M, Pfirrmann CW. Reduction of metal artifacts in patients with total hip arthroplasty with slice-encoding metal artifact correction and view-angle tilting MR imaging. Radiology. 2012;265(1):204–14.PubMedCrossRef Sutter R, Ulbrich EJ, Jellus V, Nittka M, Pfirrmann CW. Reduction of metal artifacts in patients with total hip arthroplasty with slice-encoding metal artifact correction and view-angle tilting MR imaging. Radiology. 2012;265(1):204–14.PubMedCrossRef
41.
go back to reference Toms AP, Marshall TJ, Cahir J, et al. MRI of early symptomatic metal-on-metal total hip arthroplasty: a retrospective review of radiological findings in 20 hips. Clin Radiol. 2008;63(1):49–58.PubMedCrossRef Toms AP, Marshall TJ, Cahir J, et al. MRI of early symptomatic metal-on-metal total hip arthroplasty: a retrospective review of radiological findings in 20 hips. Clin Radiol. 2008;63(1):49–58.PubMedCrossRef
42.
go back to reference Toms AP, Nolan J, Barker T, Darrah C, Malcolm P. Early failure of a Birmingham resurfacing hip replacement with lymphoreticular spread of metal debris: pre-operative diagnosis with MR. Br J Radiol. 2009;82(977):e87–91.PubMedCrossRef Toms AP, Nolan J, Barker T, Darrah C, Malcolm P. Early failure of a Birmingham resurfacing hip replacement with lymphoreticular spread of metal debris: pre-operative diagnosis with MR. Br J Radiol. 2009;82(977):e87–91.PubMedCrossRef
43.
go back to reference Toms AP, Smith-Bateman C, Malcolm PN, Cahir J, Graves M. Optimization of metal artefact reduction (MAR) sequences for MRI of total hip prostheses. Clin Radiol. 2010;65(6):447–52.PubMedCrossRef Toms AP, Smith-Bateman C, Malcolm PN, Cahir J, Graves M. Optimization of metal artefact reduction (MAR) sequences for MRI of total hip prostheses. Clin Radiol. 2010;65(6):447–52.PubMedCrossRef
44.
go back to reference van der Weegen W, Smolders JM, Sijbesma T, Hoekstra HJ, Brakel K, van Susante JL. High incidence of pseudotumours after hip resurfacing even in low risk patients; results from an intensified MRI screening protocol. Hip Int. 2013;3(23):243–9.CrossRef van der Weegen W, Smolders JM, Sijbesma T, Hoekstra HJ, Brakel K, van Susante JL. High incidence of pseudotumours after hip resurfacing even in low risk patients; results from an intensified MRI screening protocol. Hip Int. 2013;3(23):243–9.CrossRef
45.
go back to reference White LM, Kim JK, Mehta M, et al. Complications of total hip arthroplasty: MR imaging-initial experience. Radiology. 2000;215(1):254–62.PubMed White LM, Kim JK, Mehta M, et al. Complications of total hip arthroplasty: MR imaging-initial experience. Radiology. 2000;215(1):254–62.PubMed
46.
go back to reference Wynn-Jones H, Macnair R, Wimhurst J, et al. Silent soft tissue pathology is common with a modern metal-on-metal hip arthroplasty. Acta Orthop. 2011;82(3):301–7.PubMedCrossRef Wynn-Jones H, Macnair R, Wimhurst J, et al. Silent soft tissue pathology is common with a modern metal-on-metal hip arthroplasty. Acta Orthop. 2011;82(3):301–7.PubMedCrossRef
47.
go back to reference Yanny S, Cahir JG, Barker T, et al. MRI of aseptic lymphocytic vasculitis-associated lesions in metal-on-metal hip replacements. AJR Am J Roentgenol. 2012;198(6):1394–402.PubMedCrossRef Yanny S, Cahir JG, Barker T, et al. MRI of aseptic lymphocytic vasculitis-associated lesions in metal-on-metal hip replacements. AJR Am J Roentgenol. 2012;198(6):1394–402.PubMedCrossRef
Metadata
Title
Imaging Metal-on-Metal Hip Replacements: the Norwich Experience
Authors
Marianna S. Thomas, FRCR
James A. Wimhurst, FRCS(Orth)
John F. Nolan, FRCS(Orth)
Andoni P. Toms, FRCR, PhD
Publication date
01-10-2013
Publisher
Springer US
Published in
HSS Journal ® / Issue 3/2013
Print ISSN: 1556-3316
Electronic ISSN: 1556-3324
DOI
https://doi.org/10.1007/s11420-013-9357-5

Other articles of this Issue 3/2013

HSS Journal ® 3/2013 Go to the issue