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01-01-2008 | Original Paper

Two new lignan glucosides from the fruit of Vitex cannabifolia

Authors: Toru Yamasaki, Tetsuro Kawabata, Chikako Masuoka, Junei Kinjo, Tsuyoshi Ikeda, Toshihiro Nohara, Masateru Ono

Published in: Journal of Natural Medicines | Issue 1/2008

Abstract

Two new phenyldihydronaphthalene-type lignan glucosides, vitecannasides A (1) and B (2) were isolated from the fruit of Vitex cannabifolia Sieb. et. Zucc. (Verbenaceae) along with the six known lignan derivatives (3–8), four known iridoid glucosides (9–12), three known flavonoids (13–15), and one known phenylbutanone glucoside (16). Their chemical structures were determined on the basis of spectroscopic data as well as chemical evidence. The scavenging effect of 1, 2, and 11–16 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 2, 14, and 15 exhibited stronger activity than that of l-cysteine. Especially, 14 and 15 showed more potent activity than that of α-tocopherol.

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Title: Two new lignan glucosides from the fruit of Vitex cannabifolia
Authors: Toru Yamasaki
Tetsuro Kawabata
Chikako Masuoka
Junei Kinjo
Tsuyoshi Ikeda
Toshihiro Nohara
Masateru Ono
Publication date: 01-01-2008
Publisher: Springer-Verlag
Published in: Journal of Natural Medicines / Issue 1/2008
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-007-0184-1

At a glance: The STEP trials

Springer Medicine

Two new lignan glucosides from the fruit of Vitex cannabifolia

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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