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Journal of Natural Medicines
Published in: Journal of Natural Medicines 1/2008

01-01-2008 | Note

Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats

Authors: B. Sangameswaran, B. Jayakar

Published in: Journal of Natural Medicines | Issue 1/2008

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Abstract

Anti-diabetic, anti-hyperlipidemic and spermatogenic effects were studies with methanolic extract of stem of Amaranthus spinosus Linn (Family: Amaranthaceae) in diabetic rats. In streptozotocin (STZ)-induced diabetic rats, it was observed that both the standard drug (Glibenclamide) and methanolic extract of Amaranthus spinosus Linn. significantly exhibited control of blood glucose level on a 15day model. Further, the methanolic extract also showed significant anti-hyperlipidemic and spermatogenic effects in STZ-induced diabetic rats. The methanolic extract has also accelerated the process of spermatogenesis by increasing the sperm count and accessory sex organ weights. The present investigation of the plant established some pharmacological evidence to support the folklore claim that it is used as an anti-diabetic.
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Metadata
Title
Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats
Authors
B. Sangameswaran
B. Jayakar
Publication date
01-01-2008
Publisher
Springer-Verlag
Published in
Journal of Natural Medicines / Issue 1/2008
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI
https://doi.org/10.1007/s11418-007-0189-9

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