Skip to main content
Top
Published in: Sleep and Breathing 2/2022

30-07-2021 | Sleep Apnea | Sleep Breathing Physiology and Disorders • Original Article

Factors affecting compliance with positive airway pressure therapy in obstructive sleep apnea

Authors: Merve Ercelik, Ege Gulec Balbay, Pınar Yıldız Gulhan, Sengul Cangur, Peri Meram Arbak, Fuat Aytekin, Mehmet Fatih Elverisli

Published in: Sleep and Breathing | Issue 2/2022

Login to get access

Abstract

Objective

To investigate the factors affecting compliance with positive airway pressure (PAP) therapy and establish the relationship between compliance and pulmonary function tests (PFT) in patients with OSA.

Material and methods

In this prospective study, patients with OSA using PAP devices were questioned about the complaints related to the device. Depression and anxiety scales along with PFT parameters were also assessed.

Results

Of 98 participants, 63% were men. The mean age was 52.0 ± 9.6 years. Sixty-seven percent of the patients were compliant with their devices. A significant difference was observed between the proportion of the participants compliant or non-compliant with the device, based on OSA severity (p < 0.05). Beck depression inventory (BDI) and Beck anxiety inventory (BAI) scores of the compliant patients were significantly lower than those of the non-compliant patients (p < 0.001, p = 0.044, respectively). No statistically significant difference was detected between the groups regarding individual pulmonary function tests (p > 0.05). The rates of nasal mask use, not having difficulty in tolerating CPAP, falling asleep, absence of abdominal distension, no facial sores, no air leakage, patients benefiting from the device, reduction in daytime sleepiness, and the belief that they are receiving appropriate therapy in participants compliant with the device were higher than those in non-compliant participants (p < 0.05). The rates of claustrophobia and discomfort due to pressure were significantly lower in patients compliant with the device than in the non-compliant patients (p < 0.05).

Conclusion

While no relationship was detected between PFT parameters and PAP therapy compliance, significant factors affecting the device compliance were detected.
Literature
1.
go back to reference Sleep (1999) Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force 22(5):667–689 Sleep (1999) Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force 22(5):667–689
2.
go back to reference Balbay EG, Ataoglu O, Ercelik M, Sahin IE, Admıs O, Arbak P (2020) Serum clara cell protein-16 (CC-16) level in non-smoker obstructive sleep apnea syndrome patients. Sleep Breath 24:1607–1612CrossRef Balbay EG, Ataoglu O, Ercelik M, Sahin IE, Admıs O, Arbak P (2020) Serum clara cell protein-16 (CC-16) level in non-smoker obstructive sleep apnea syndrome patients. Sleep Breath 24:1607–1612CrossRef
3.
go back to reference Jennum P, Tonnesen P, Ibsen R, Kjelberg J (2017) Obstructive sleep apnea: effect of comorbidities and positive airway pressure on all-cause mortality. Sleep Med 36:62–66CrossRef Jennum P, Tonnesen P, Ibsen R, Kjelberg J (2017) Obstructive sleep apnea: effect of comorbidities and positive airway pressure on all-cause mortality. Sleep Med 36:62–66CrossRef
4.
go back to reference Strohl K, Redline S (1986) Nasal CPAP therapy, upper airway muscle activation and obstructive sleep apnea. Am Rev Respir Dis 134:555–558PubMed Strohl K, Redline S (1986) Nasal CPAP therapy, upper airway muscle activation and obstructive sleep apnea. Am Rev Respir Dis 134:555–558PubMed
5.
go back to reference Kribbs NB, Pack AI, Kline LR et al (1993) Objective measurement of patterns of nasal CPAP use by patients with obstructive sleep apnea. Am Rev Respir Dis 147(4):887–895CrossRef Kribbs NB, Pack AI, Kline LR et al (1993) Objective measurement of patterns of nasal CPAP use by patients with obstructive sleep apnea. Am Rev Respir Dis 147(4):887–895CrossRef
6.
go back to reference Afşar GC, Saraç S, Babalık A, Calışır HC (2018) Defining of the relationship between lung volumes, airway resistance and the apnea-hypopnea index. J Turk Sleep Med 5:6–11CrossRef Afşar GC, Saraç S, Babalık A, Calışır HC (2018) Defining of the relationship between lung volumes, airway resistance and the apnea-hypopnea index. J Turk Sleep Med 5:6–11CrossRef
7.
go back to reference Weaver TE, Grunstein RR (2008) Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 5:173–178CrossRef Weaver TE, Grunstein RR (2008) Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 5:173–178CrossRef
8.
go back to reference Berry RB, Budhiraja R, Gottlieb DJ et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 8(5):597–619CrossRef Berry RB, Budhiraja R, Gottlieb DJ et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 8(5):597–619CrossRef
9.
go back to reference Wolkove N, Baltzan M, Kamel H, Dabrusin R, Palayew M (2008) Long-term compliance with continuous positive airway pressure in patients with obstructive sleep apnea. Can Respir J 15:365–369CrossRef Wolkove N, Baltzan M, Kamel H, Dabrusin R, Palayew M (2008) Long-term compliance with continuous positive airway pressure in patients with obstructive sleep apnea. Can Respir J 15:365–369CrossRef
10.
go back to reference Poulet C, Veale D, Arnol N, Levy P, Pepin JL, Tyrrell J (2000) Psychological variables as predictors of adherence to treatment by continuous positive airway pressure. Sleep Med 10:993–999CrossRef Poulet C, Veale D, Arnol N, Levy P, Pepin JL, Tyrrell J (2000) Psychological variables as predictors of adherence to treatment by continuous positive airway pressure. Sleep Med 10:993–999CrossRef
11.
go back to reference Uyar M, Elbek O, Mete A et al (2012) Factors influencing compliance with continuous positive airway pressure ventilation in obstructive sleep apnea syndrome. Tuberk Toraks 60:47–51CrossRef Uyar M, Elbek O, Mete A et al (2012) Factors influencing compliance with continuous positive airway pressure ventilation in obstructive sleep apnea syndrome. Tuberk Toraks 60:47–51CrossRef
12.
go back to reference Wild MR, Engleman HM, Douglas NJ et al (2004) Can psychological factors help us to determine adherence to CPAP? A prospective study. Eur Respir J 24:461–5CrossRef Wild MR, Engleman HM, Douglas NJ et al (2004) Can psychological factors help us to determine adherence to CPAP? A prospective study. Eur Respir J 24:461–5CrossRef
13.
go back to reference Dolan DC, Okonkwo R, Gfullner F et al (2009) Longitudinal comparison study of pressure relief (C-Flex) vs. CPAP in OSA patients. Sleep Breath 13:73–7CrossRef Dolan DC, Okonkwo R, Gfullner F et al (2009) Longitudinal comparison study of pressure relief (C-Flex) vs. CPAP in OSA patients. Sleep Breath 13:73–7CrossRef
14.
go back to reference Marshall NS, Neill AM, Campbell AJ (2008) Randomised trial of compliance with flexible (C-Flex) and standard continuous positive airway pressure for severe obstructive sleep apnea. Sleep Breath 12:393–396CrossRef Marshall NS, Neill AM, Campbell AJ (2008) Randomised trial of compliance with flexible (C-Flex) and standard continuous positive airway pressure for severe obstructive sleep apnea. Sleep Breath 12:393–396CrossRef
15.
go back to reference Bakker J, Campbell A, Neill A (2010) Randomized controlled trial comparing flexible and continuous positive airway pressure delivery: effects on compliance, objective and subjective sleepiness and vigilance. Sleep 33:523–529CrossRef Bakker J, Campbell A, Neill A (2010) Randomized controlled trial comparing flexible and continuous positive airway pressure delivery: effects on compliance, objective and subjective sleepiness and vigilance. Sleep 33:523–529CrossRef
16.
go back to reference Massie CA, Hart RW (2003) Clinical outcomes related to interface type in patients with obstructive sleep apnea/hypopnea syndrome who are using continuous positive airway pressure. Chest 2003123(4):1112–1118CrossRef Massie CA, Hart RW (2003) Clinical outcomes related to interface type in patients with obstructive sleep apnea/hypopnea syndrome who are using continuous positive airway pressure. Chest 2003123(4):1112–1118CrossRef
17.
go back to reference Borel JC, Tamisier R, Dias-Domingos S et al (2013) Scientific Council of The Sleep Registry of the French Federation of Pneumology (OSFP). Type of mask may impact on continuous positive airway pressure adherence in apneic patients. PLoS One 8:64382CrossRef Borel JC, Tamisier R, Dias-Domingos S et al (2013) Scientific Council of The Sleep Registry of the French Federation of Pneumology (OSFP). Type of mask may impact on continuous positive airway pressure adherence in apneic patients. PLoS One 8:64382CrossRef
18.
go back to reference Khanna R, Kline LR (2003) A prospective 8week trial of nasal interfaces vs. a novel oral interface (Oracle) for treatment of obstructive sleep apnea hypopnea syndrome. Sleep Med 4:333–338CrossRef Khanna R, Kline LR (2003) A prospective 8week trial of nasal interfaces vs. a novel oral interface (Oracle) for treatment of obstructive sleep apnea hypopnea syndrome. Sleep Med 4:333–338CrossRef
19.
go back to reference Richards D, Bartlett DJ, Wong K, Malouff J, Grunstein RR (2007) Increased adherence to CPAP with a group cognitive behavioral treatment intervention: a randomized trial. Sleep 30:635–640CrossRef Richards D, Bartlett DJ, Wong K, Malouff J, Grunstein RR (2007) Increased adherence to CPAP with a group cognitive behavioral treatment intervention: a randomized trial. Sleep 30:635–640CrossRef
20.
go back to reference Weaver TE, Maislin G, Dinges DF, Younger J, Cantor C, McCloskey S et al (2003) Self-efficacy in sleep apnea: instrument development and patient perceptions of obstructive sleep apnea risk, treatment benefit, and volition to use continuous positive airway press. Sleep 26:727–732CrossRef Weaver TE, Maislin G, Dinges DF, Younger J, Cantor C, McCloskey S et al (2003) Self-efficacy in sleep apnea: instrument development and patient perceptions of obstructive sleep apnea risk, treatment benefit, and volition to use continuous positive airway press. Sleep 26:727–732CrossRef
21.
go back to reference Engleman HM, Wild MR (2003) Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS). Sleep Med Rev 7:81–99CrossRef Engleman HM, Wild MR (2003) Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS). Sleep Med Rev 7:81–99CrossRef
22.
go back to reference Sanders MH, Martin RJ, Pennock BE, Rogers RM (1981) The detection of sleep apnea in the awake patient. The ‘saw-tooth’ sign. JAMA 245:2414–2418CrossRef Sanders MH, Martin RJ, Pennock BE, Rogers RM (1981) The detection of sleep apnea in the awake patient. The ‘saw-tooth’ sign. JAMA 245:2414–2418CrossRef
23.
go back to reference Katz I, Zarne N, Slutsky S, Rebuck S, Hoffstein V (1990) An evaluation of flow-volume curves as a screening test for obstructive sleep apnea. Chest 98:337–340CrossRef Katz I, Zarne N, Slutsky S, Rebuck S, Hoffstein V (1990) An evaluation of flow-volume curves as a screening test for obstructive sleep apnea. Chest 98:337–340CrossRef
24.
go back to reference Zerah-Lancner F, Lofaso F, Coste A et al (1997) Pulmonary function in obese snorers with or without sleep apnea syndrome. Am J Respir Crit Care Med 156(2 Pt 1):522–527CrossRef Zerah-Lancner F, Lofaso F, Coste A et al (1997) Pulmonary function in obese snorers with or without sleep apnea syndrome. Am J Respir Crit Care Med 156(2 Pt 1):522–527CrossRef
25.
go back to reference Stauffer JL, White D, Zwillich W (1990) Pulmonary function in obstructive sleep apnea relationships to pharyngeal resistance and cross sectional area. Chest 97:302–307CrossRef Stauffer JL, White D, Zwillich W (1990) Pulmonary function in obstructive sleep apnea relationships to pharyngeal resistance and cross sectional area. Chest 97:302–307CrossRef
26.
go back to reference Krieger J, Weitzenblum E, Vandevenne A, Stierle JL, Kurtz D (1985) Flow volume curve abnormalities and obstructive sleep apnea syndrome. Chest 87:163–167CrossRef Krieger J, Weitzenblum E, Vandevenne A, Stierle JL, Kurtz D (1985) Flow volume curve abnormalities and obstructive sleep apnea syndrome. Chest 87:163–167CrossRef
27.
go back to reference Abdeyrim A, Zhang Y, Li N, Zhao M, Wang Y, Yao X, Keyoumu Y, Yin T (2015) Impact of obstructive sleep apnea on lung volumes and mechanical properties of the respiratory system in overweight and obese individuals. BMC Pulm Med 15:76CrossRef Abdeyrim A, Zhang Y, Li N, Zhao M, Wang Y, Yao X, Keyoumu Y, Yin T (2015) Impact of obstructive sleep apnea on lung volumes and mechanical properties of the respiratory system in overweight and obese individuals. BMC Pulm Med 15:76CrossRef
Metadata
Title
Factors affecting compliance with positive airway pressure therapy in obstructive sleep apnea
Authors
Merve Ercelik
Ege Gulec Balbay
Pınar Yıldız Gulhan
Sengul Cangur
Peri Meram Arbak
Fuat Aytekin
Mehmet Fatih Elverisli
Publication date
30-07-2021
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 2/2022
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-021-02447-4

Other articles of this Issue 2/2022

Sleep and Breathing 2/2022 Go to the issue

Sleep Breathing Physiology and Disorders • Original Article

Risk factors for non-positional obstructive sleep apnea–hypopnea syndrome