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01-12-2020 | Sleep Apnea | Review

Metabolomics, sleepiness, and sleep duration in sleep apnea

Authors: Idiatou Diallo, Victoria M. Pak

Published in: Sleep and Breathing | Issue 4/2020

Abstract

Purpose

Although the mechanism is unclear, daytime sleepiness, a common sequela of obstructive sleep apnea (OSA), has been found to be correlated with a adverse cardiovascular outcomes. Reviewing metabolomics mechanisms of sleep disturbances and cardiovascular disease may help to explain this correlation.

Methods

This review examines the current literature on the relationships between sleepiness, sleep duration, and metabolites in sleep apnea.

Results

Although there is a lack of comprehensive literature in this emerging area, existing studies point to a variety of metabolites in different pathways that are associated with sleepiness and sleep duration.

Conclusion

Advancing metabolomics research in sleep apnea will guide symptom research and provide alternate and novel opportunities for effective treatment for patients with OSA.

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Title: Metabolomics, sleepiness, and sleep duration in sleep apnea
Authors: Idiatou Diallo
Victoria M. Pak
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keywords: Sleep Apnea
Polysomnography
Published in: Sleep and Breathing / Issue 4/2020
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-019-01969-2

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