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01-03-2020 | Sleep Apnea | Sleep Breathing Physiology and Disorders • Original Article

The effects of threshold inspiratory muscle training in patients with obstructive sleep apnea: a randomized experimental study

Authors: Huei-Chen Lin, Ling-Ling Chiang, Jun-Hui Ong, Kun-ling Tsai, Ching-Hsia Hung, Cheng-Yu Lin

Published in: Sleep and Breathing | Issue 1/2020

Abstract

Objectives

Patients with obstructive sleep apnea (OSA) (an obstructed airway and intermittent hypoxia) negatively affect their respiratory muscles. We evaluated the effects of a 12-week threshold inspiratory muscle training (TIMT) program on OSA severity, daytime sleepiness, and pulmonary function in newly diagnosed OSA.

Methods

Sixteen patients with moderate-to-severe OSA were randomly assigned to a TIMT group and 6 to a control group. The home-based TIMT program was 30–45 min/day, 5 days/week, for 12 weeks using a TIMT training device. Their apnea-hypopnea index (AHI), Epworth sleepiness scale (ESS), and forced vital capacity (FVC) scores were evaluated pre- and post-treatment. Polysomnographic (PSG) analysis showed that 9 TIMT-group patients had positively responded (TIMT-responder group: post-treatment AHI < pre-treatment) and that 7 had not (TIMT non-responder group: post-treatment AHI > pre-treatment).

Results

Post-treatment AHI and ESS scores were significantly (both P < 0.05) lower 6% and 20.2%, respectively. A baseline AHI ≤ 29.0/h predicted TIMT-responder group patients (sensitivity 77.8%; specificity 85.7%). FVC was also significantly (P < 0.05) higher 7.2%. Baseline AHI and FEV_6.0 were significant predictors of successful TIMT-responder group intervention. OSA severity and daytime sleepiness were also significantly attenuated.

Conclusions

Home-based TIMT training is simple, efficacious, and cost-effective.

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Title: The effects of threshold inspiratory muscle training in patients with obstructive sleep apnea: a randomized experimental study
Authors: Huei-Chen Lin
Ling-Ling Chiang
Jun-Hui Ong
Kun-ling Tsai
Ching-Hsia Hung
Cheng-Yu Lin
Publication date: 01-03-2020
Publisher: Springer International Publishing
Keywords: Sleep Apnea
Polysomnography
Published in: Sleep and Breathing / Issue 1/2020
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-019-01862-y

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