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Sleep and Breathing
Published in: Sleep and Breathing 4/2012

01-12-2012 | Review

Obstructive sleep apnea and kidney disease: is there any direct link?

Author: Aibek E. Mirrakhimov

Published in: Sleep and Breathing | Issue 4/2012

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Abstract

Background

Obstructive sleep apnea (OSA) is a common and underrecognized disorder affecting at least 2% and 4% of women and men, respectively. Chronic kidney disease (CKD), on the other hand, affects around 13% of US adults. Both of these conditions share some risk factors such as age, obesity, and smoking and are associated with increased cardiovascular morbidity and mortality. By itself OSA may play a role in the development of arterial hypertension, metabolic syndrome, type 2 diabetes mellitus, and dyslipidemia with potential impact on CKD development and/or progression. But the data regarding OSA and CKD are relatively scant.

Discussion

Moreover, several studies had shown possible harmful effects on kidney function independent from conventional risk factors. CKD is associated with excessive fluid volume, with potential shift during recumbency towards the neck area with increased upper airway resistance. Thus, OSA and CKD may be the results of each other and when present together may impose much greater cardiovascular risk than either disease alone.
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Metadata
Title
Obstructive sleep apnea and kidney disease: is there any direct link?
Author
Aibek E. Mirrakhimov
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Sleep and Breathing / Issue 4/2012
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-011-0624-8

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