Skip to main content
Top
Published in: Sleep and Breathing 3/2005

01-09-2005 | Original Article

Insomnia complaints in patients evaluated for obstructive sleep apnea

Authors: Suzanne B. Krell, Vishesh K. Kapur

Published in: Sleep and Breathing | Issue 3/2005

Login to get access

Abstract

Obstructive sleep apnea (OSA) and insomnia are among the most common sleep diagnoses encountered in the sleep clinic population, however little is known about potential interactions or associations between the two disorders. This retrospective, cross-sectional study was designed to determine the prevalence of insomnia complaints in patients undergoing evaluation for OSA and to ascertain which clinical and polysomnographic features are associated with insomnia. Of 255 consecutive patients who underwent polysomnography for clinically suspected OSA, 54.9% reported a complaint of insomnia: 33.4% reported difficulty initiating sleep, 38.8% difficulty maintaining sleep, and 31.4% early morning awakenings. Insomnia complaints were noted more commonly in patients without significant sleep-disordered breathing [apnea hypopnea index (AHI)<10; 81.5%] vs those with sleep-disordered breathing (AHI≥10; 51.8%); p=0.01. Clinical factors associated with insomnia included female gender, psychiatric diagnoses, chronic pain, the absence of regular alcohol use, restless leg symptoms, and reports of nocturnal kicking. Polysomnographic factors associated with insomnia included lower AHI and lower desaturation index (DI). In the subgroup of patients with significant sleep-disordered breathing (AHI≥10, n=228), there was no association between insomnia complaints and AHI or DI. These results suggest that insomnia is a common complaint in patients being evaluated for OSA, but it is not strongly associated with sleep-disordered breathing and may instead reflect other coexisting factors.
Literature
1.
go back to reference Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disorder breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disorder breathing among middle-aged adults. N Engl J Med 328:1230–1235CrossRefPubMed
2.
go back to reference Chervin RD (2000) Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea. Chest 118:372–379CrossRefPubMed Chervin RD (2000) Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea. Chest 118:372–379CrossRefPubMed
3.
go back to reference Bixler EO, Kales A, Soldatos CR, Kales JD, Healey S (1979) Prevalence of sleep disorders in the Los Angeles metropolitan area. Am J Psychiatry 146:1257–1262 Bixler EO, Kales A, Soldatos CR, Kales JD, Healey S (1979) Prevalence of sleep disorders in the Los Angeles metropolitan area. Am J Psychiatry 146:1257–1262
4.
go back to reference Mellinger GD, Balter MD, Uhlenhuth EH (1985) Insomnia and its treatment. Prevalence and correlates. Arch Gen Psychiatry 42:225–232PubMed Mellinger GD, Balter MD, Uhlenhuth EH (1985) Insomnia and its treatment. Prevalence and correlates. Arch Gen Psychiatry 42:225–232PubMed
5.
go back to reference Katz DA, McHorney CA (2002) The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract 51:229–235PubMed Katz DA, McHorney CA (2002) The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract 51:229–235PubMed
6.
go back to reference Ancoli-Israel S, Roth T (1999) Characteristics of insomnia in the US: results of the 1991 National Sleep Foundation Survey. Sleep 22:s347–s353PubMed Ancoli-Israel S, Roth T (1999) Characteristics of insomnia in the US: results of the 1991 National Sleep Foundation Survey. Sleep 22:s347–s353PubMed
7.
go back to reference Klink ME, Quan SF, Kaltenborn WT, Lebowitz MD (1992) Risk factors associated with complaints of insomnia in a general adult population. Arch Intern Med 152:1634–1637CrossRefPubMed Klink ME, Quan SF, Kaltenborn WT, Lebowitz MD (1992) Risk factors associated with complaints of insomnia in a general adult population. Arch Intern Med 152:1634–1637CrossRefPubMed
8.
go back to reference Chesson A Jr, Hartse K, Anderson WM et al (2000) Practice parameters for the evaluation of chronic insomnia: an American Academy of Sleep Medicine report; Standards of Practice Committee of the American Academy of Sleep Medicine. Sleep 23:237–241PubMed Chesson A Jr, Hartse K, Anderson WM et al (2000) Practice parameters for the evaluation of chronic insomnia: an American Academy of Sleep Medicine report; Standards of Practice Committee of the American Academy of Sleep Medicine. Sleep 23:237–241PubMed
9.
go back to reference Sateia MJ, Doghramji K, Hauri PJ, Morin CM (2000) Evaluation of chronic insomnia. An American Academy of Sleep Medicine review. Sleep 23:243–263PubMed Sateia MJ, Doghramji K, Hauri PJ, Morin CM (2000) Evaluation of chronic insomnia. An American Academy of Sleep Medicine review. Sleep 23:243–263PubMed
10.
go back to reference Edinger JD, Hoelscher TJ, Webb MD et al (1989) Polysomnographic assessment of DIMS: empirical evaluation of its diagnostic value. Sleep 12:315–322PubMed Edinger JD, Hoelscher TJ, Webb MD et al (1989) Polysomnographic assessment of DIMS: empirical evaluation of its diagnostic value. Sleep 12:315–322PubMed
11.
go back to reference Coleman RM, Roffwarg HP, Kennedy SJ et al (1982) Sleep–wake disorders based on a polysomnographic diagnosis: a national cooperative study. JAMA 247:997–1003PubMedCrossRef Coleman RM, Roffwarg HP, Kennedy SJ et al (1982) Sleep–wake disorders based on a polysomnographic diagnosis: a national cooperative study. JAMA 247:997–1003PubMedCrossRef
12.
go back to reference Zorick FJ, Roth T, Hartze KM, Piccione PM, Stepanski EJ (1981) Evaluation and diagnosis of persistent Insomnia. Am J Psychiatry 138:769–773PubMed Zorick FJ, Roth T, Hartze KM, Piccione PM, Stepanski EJ (1981) Evaluation and diagnosis of persistent Insomnia. Am J Psychiatry 138:769–773PubMed
13.
go back to reference Jacobs EA, Reynolds CF III, Kupfer DJ, Lovin PA, Ehrenpreis AB (1988) The role of polysomnography in the differential diagnosis of chronic insomnia. Am J Psychiatry 145:346–349PubMed Jacobs EA, Reynolds CF III, Kupfer DJ, Lovin PA, Ehrenpreis AB (1988) The role of polysomnography in the differential diagnosis of chronic insomnia. Am J Psychiatry 145:346–349PubMed
14.
go back to reference Roehrs T, Zorick F, Sicklesteel J, Wittig R, Roth T (1983) Age-related sleep–wake disorders at a sleep disorders center. J Am Geriatr Soc 132:364–370 Roehrs T, Zorick F, Sicklesteel J, Wittig R, Roth T (1983) Age-related sleep–wake disorders at a sleep disorders center. J Am Geriatr Soc 132:364–370
15.
go back to reference Krakow B, Melendrez D, Pederson B et al (2001) Complex insomnia: insomnia and sleep-disordered breathing in a consecutive series of crime victims with nightmares and PTSD. Biol Psychiatry 49:948–953CrossRefPubMed Krakow B, Melendrez D, Pederson B et al (2001) Complex insomnia: insomnia and sleep-disordered breathing in a consecutive series of crime victims with nightmares and PTSD. Biol Psychiatry 49:948–953CrossRefPubMed
16.
go back to reference Guilleminault C, Palombini L, Poyares D, Chowdhuri S (2002) Chronic insomnia, postmenopausal women, and sleep disordered breathing: part 1. Frequency of sleep-disordered breathing in a cohort. J Psychosom Res 53:611–615CrossRefPubMed Guilleminault C, Palombini L, Poyares D, Chowdhuri S (2002) Chronic insomnia, postmenopausal women, and sleep disordered breathing: part 1. Frequency of sleep-disordered breathing in a cohort. J Psychosom Res 53:611–615CrossRefPubMed
17.
go back to reference Krakow B, Melendrez D, Ferreira E et al (2001) Prevalence of insomnia symptoms in patients with sleep-disordered breathing. Chest 120:1923–1929CrossRefPubMed Krakow B, Melendrez D, Ferreira E et al (2001) Prevalence of insomnia symptoms in patients with sleep-disordered breathing. Chest 120:1923–1929CrossRefPubMed
18.
go back to reference Rechtschaffen A, Kales A (1968) A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects: National Institutes of Health publication 204. US Department of Health, Education, and Welfare, Washington, DC Rechtschaffen A, Kales A (1968) A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects: National Institutes of Health publication 204. US Department of Health, Education, and Welfare, Washington, DC
19.
go back to reference Ambrogetti A, Olson LG, Saunders NA (1991) Differences in the symptoms of men and women with obstructive sleep apnea. Aust N Z J Med 21:863–866PubMed Ambrogetti A, Olson LG, Saunders NA (1991) Differences in the symptoms of men and women with obstructive sleep apnea. Aust N Z J Med 21:863–866PubMed
20.
go back to reference Ohayon MM, Roth T (2001) What are the contributing factors for insomnia in the general population? J Psychosom Res 51:745–755CrossRefPubMed Ohayon MM, Roth T (2001) What are the contributing factors for insomnia in the general population? J Psychosom Res 51:745–755CrossRefPubMed
21.
go back to reference Kim K, Uchiyama M, Okawa M, Liu X, Ogihara R (2000) An epidemiological study of insomnia among the Japanese general population. Sleep 23:41–47PubMed Kim K, Uchiyama M, Okawa M, Liu X, Ogihara R (2000) An epidemiological study of insomnia among the Japanese general population. Sleep 23:41–47PubMed
22.
go back to reference Standards of Practice Committee of the American Sleep Disorders Association (1995) Practice parameters for the use of polysomnography in the evaluation of insomnia. Sleep 18:55–57 Standards of Practice Committee of the American Sleep Disorders Association (1995) Practice parameters for the use of polysomnography in the evaluation of insomnia. Sleep 18:55–57
23.
go back to reference Norman RG, Ahmed MM, Walsleben JA, Rapoport DM (1997) Detection of respiratory events during NPSG: nasal cannula/pressure sensor versus thermistor. Sleep 20:1175–1184PubMed Norman RG, Ahmed MM, Walsleben JA, Rapoport DM (1997) Detection of respiratory events during NPSG: nasal cannula/pressure sensor versus thermistor. Sleep 20:1175–1184PubMed
24.
go back to reference Bixler EO, Vgontzas AN, Lin A, Vela-Bueno A, Kales A (2002) Insomnia in central Pennsylvania. J Psychosom Res 53:589–592CrossRefPubMed Bixler EO, Vgontzas AN, Lin A, Vela-Bueno A, Kales A (2002) Insomnia in central Pennsylvania. J Psychosom Res 53:589–592CrossRefPubMed
25.
go back to reference Montplaisir J, Boucher S, Poirer G, Lavigne G, Lapierre O, Lesperance P (1997) Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria. Mov Disord 12:61–65CrossRefPubMed Montplaisir J, Boucher S, Poirer G, Lavigne G, Lapierre O, Lesperance P (1997) Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria. Mov Disord 12:61–65CrossRefPubMed
26.
go back to reference Engleman HM, Asgari-Jirhandeh N, McLeod AL, Ramsay CF, Deary IJ, Douglas NJ (1996) Self-reported use of CPAP and benefits of CPAP therapy. Chest 109:1470–1476PubMedCrossRef Engleman HM, Asgari-Jirhandeh N, McLeod AL, Ramsay CF, Deary IJ, Douglas NJ (1996) Self-reported use of CPAP and benefits of CPAP therapy. Chest 109:1470–1476PubMedCrossRef
Metadata
Title
Insomnia complaints in patients evaluated for obstructive sleep apnea
Authors
Suzanne B. Krell
Vishesh K. Kapur
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
Sleep and Breathing / Issue 3/2005
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-005-0026-x

Other articles of this Issue 3/2005

Sleep and Breathing 3/2005 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.