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Open Access 01-04-2011 | Review Article

Optical Image-guided Surgery—Where Do We Stand?

Authors: Stijn Keereweer, Jeroen D. F. Kerrebijn, Pieter B. A. A. van Driel, Bangwen Xie, Eric L. Kaijzel, Thomas J. A. Snoeks, Ivo Que, Merlijn Hutteman, Joost R. van der Vorst, J. Sven D. Mieog, Alexander L. Vahrmeijer, Cornelis J. H. van de Velde, Robert J. Baatenburg de Jong, Clemens W. G. M. Löwik

Published in: Molecular Imaging and Biology | Issue 2/2011

Abstract

In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for the prognosis of the patient, relies on the visual appearance and palpation of the tumor. Optical imaging techniques provide real-time visualization of the tumor, warranting intra-operative image-guided surgery. Within this field, imaging in the near-infrared light spectrum offers two essential advantages: increased tissue penetration of light and an increased signal-to-background-ratio of contrast agents. In this article, we review the various techniques, contrast agents, and camera systems that are currently used for image-guided surgery. Furthermore, we provide an overview of the wide range of molecular contrast agents targeting specific hallmarks of cancer and we describe perspectives on its future use in cancer surgery.

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Title: Optical Image-guided Surgery—Where Do We Stand?
Authors: Stijn Keereweer
Jeroen D. F. Kerrebijn
Pieter B. A. A. van Driel
Bangwen Xie
Eric L. Kaijzel
Thomas J. A. Snoeks
Ivo Que
Merlijn Hutteman
Joost R. van der Vorst
J. Sven D. Mieog
Alexander L. Vahrmeijer
Cornelis J. H. van de Velde
Robert J. Baatenburg de Jong
Clemens W. G. M. Löwik
Publication date: 01-04-2011
Publisher: Springer-Verlag
Published in: Molecular Imaging and Biology / Issue 2/2011
Print ISSN: 1536-1632
Electronic ISSN: 1860-2002
DOI: https://doi.org/10.1007/s11307-010-0373-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Optical Image-guided Surgery—Where Do We Stand?

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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