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Published in: International Urology and Nephrology 6/2019

Open Access 01-06-2019 | Nephrectomy | Urology - Original Paper

Renal hilar block predicts long-term success of renal auto-transplantation for loin pain hematuria syndrome

Authors: Jeffrey Campsen, Mitchell R. Bassett, Ryan O’Hara, Robin D. Kim, Eryberto Martinez, Rulon Hardman, Jeremy B. Myers, Blake Hamilton

Published in: International Urology and Nephrology | Issue 6/2019

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Abstract

Purpose

In patients with loin pain hematuria syndrome (LPHS), a response to percutaneous renal hilar blockade (RHB) and a multidisciplinary team (MDT) evaluation predicts patient’s potential renal auto-transplantation (RAT) success.

Methods

A pain assessment was performed using a 0–10 numeric pain rating scale prior to a percutaneous RHB under CT guidance. If the pain score was reduced > 50% immediately after the RHB, patients were evaluated for RAT by a MDT. Pre-operative and 1-year post-operative quality-of-life surveys were administered to each RAT patient.

Results

43 LPHS patients were referred for RHB. Of the 38 patients who received a RHB, 31 had > 50% reduction in pain scores. Pre- and post-RHB mean pain scores were 6/10 and 0.7/10, respectively, in patients who had > 50% reduction in pain. 22 of the patients who responded favorably then proceeded to RAT. Twelve patients had at least 1-year follow-up after RAT. All patients had a meaningful decrease in their pain. Mean pain score at 1 year was 0.8/10 for an 85% overall reduction in pain. 92% of patients experienced a ≥ 50% reduction in pain at 1 year. Mean Beck Depression Inventory (BDI) score (0–66) 1 year after RAT decreased from 25.2 pre-op (moderate depression) to 12.8 post-op (minimal depression).

Conclusions

A MDT approach utilizing a RHB should be considered as a tool to select appropriate LPHS patients for RAT to achieve long-term success in reducing chronic pain and depression while increasing quality of life.
Literature
1.
go back to reference Little PJ, Sloper JS, De Warderner HE (1967) A syndrome of loin pain and haematuria associated with disease of peripheral renal arteries. QJM Int J Med 36(2):253–259 Little PJ, Sloper JS, De Warderner HE (1967) A syndrome of loin pain and haematuria associated with disease of peripheral renal arteries. QJM Int J Med 36(2):253–259
2.
go back to reference Zubair AS, Salameh H, Erickson SB et al (2016) Loin pain hematuria syndrome. Clin Kidney J 9(1):128–134CrossRefPubMed Zubair AS, Salameh H, Erickson SB et al (2016) Loin pain hematuria syndrome. Clin Kidney J 9(1):128–134CrossRefPubMed
3.
go back to reference Praga M, Martinez MA, Andres A et al (1998) Association of thin basement membrane nephropathy with hypercalciuria, hyperuricosuria and nephrolithiasis. Kidney Int 54:915–920CrossRefPubMed Praga M, Martinez MA, Andres A et al (1998) Association of thin basement membrane nephropathy with hypercalciuria, hyperuricosuria and nephrolithiasis. Kidney Int 54:915–920CrossRefPubMed
4.
go back to reference Greenwell TJ, Peters JL, Neild GH et al (2004) The outcome of renal denervation for managing loin pain haematuria syndrome. BJU Int 93:818–821CrossRefPubMed Greenwell TJ, Peters JL, Neild GH et al (2004) The outcome of renal denervation for managing loin pain haematuria syndrome. BJU Int 93:818–821CrossRefPubMed
5.
go back to reference Coffman KL (2009) Loin pain hematuria syndrome: a psychiatric and surgical conundrum. Curr Opin Organ Transplant 14(2):186–190PubMed Coffman KL (2009) Loin pain hematuria syndrome: a psychiatric and surgical conundrum. Curr Opin Organ Transplant 14(2):186–190PubMed
6.
go back to reference Nitschke AM, Ray CE Jr (2013) Percutaneous neurolytic celiac plexus block. Semin Interv Radiol 30(3):318–321CrossRef Nitschke AM, Ray CE Jr (2013) Percutaneous neurolytic celiac plexus block. Semin Interv Radiol 30(3):318–321CrossRef
7.
go back to reference Moeschler SM, Hoelzer BC, Eldrige JS (2013) A patient with loin hematuria syndrome and chronic flank pain treated with pulsed radiofrequency of the splanchnic nerves. Clin J Pain 29(11):26–29CrossRef Moeschler SM, Hoelzer BC, Eldrige JS (2013) A patient with loin hematuria syndrome and chronic flank pain treated with pulsed radiofrequency of the splanchnic nerves. Clin J Pain 29(11):26–29CrossRef
8.
go back to reference Gambaro G, Fulignati P, Spinelli A et al (2013) Percutaneous renal sympathetic nerve ablation for loin pain haematuria syndrome. Nephrol Dial Transplant 28(9):2393–2395CrossRefPubMed Gambaro G, Fulignati P, Spinelli A et al (2013) Percutaneous renal sympathetic nerve ablation for loin pain haematuria syndrome. Nephrol Dial Transplant 28(9):2393–2395CrossRefPubMed
9.
go back to reference Cowan NG, Banerji JS, Johnston RB et al (2015) Renal autotransplantation: 27-year experience at 2 institutions. J Urol 194(5):1357–1361CrossRefPubMed Cowan NG, Banerji JS, Johnston RB et al (2015) Renal autotransplantation: 27-year experience at 2 institutions. J Urol 194(5):1357–1361CrossRefPubMed
10.
go back to reference Harney J, Rodgers E, Campbell E et al (1994) Loin pain-hematuria syndrome: how effective is renal autotransplantation in its treatment? Urology 44(4):493–496CrossRefPubMed Harney J, Rodgers E, Campbell E et al (1994) Loin pain-hematuria syndrome: how effective is renal autotransplantation in its treatment? Urology 44(4):493–496CrossRefPubMed
11.
go back to reference Zubair AS, Cheungpasitporn W, Erickson SB et al (2016) Clinical and safety outcomes of laparoscopic nephrectomy with renal autotransplantation for the loin pain-hematuria syndrome: a 14-year longitudinal cohort study. J Evid Based Med 9(2):84–90CrossRefPubMed Zubair AS, Cheungpasitporn W, Erickson SB et al (2016) Clinical and safety outcomes of laparoscopic nephrectomy with renal autotransplantation for the loin pain-hematuria syndrome: a 14-year longitudinal cohort study. J Evid Based Med 9(2):84–90CrossRefPubMed
12.
go back to reference Parnham AP, Low A, Finch P et al (1996) Recurrent graft pain following renal autotransplantation for loin pain haematuria syndrome. Br J Urol 78(1):25–28CrossRefPubMed Parnham AP, Low A, Finch P et al (1996) Recurrent graft pain following renal autotransplantation for loin pain haematuria syndrome. Br J Urol 78(1):25–28CrossRefPubMed
13.
go back to reference Chin JL, Kloth D, Pautler SE et al (1998) Renal autotransplantation for the loin pain-hematuria syndrome: long-term followup of 26 cases. J Urol 160(4):1232–1236CrossRefPubMed Chin JL, Kloth D, Pautler SE et al (1998) Renal autotransplantation for the loin pain-hematuria syndrome: long-term followup of 26 cases. J Urol 160(4):1232–1236CrossRefPubMed
14.
go back to reference McHorney CA, Ware JE, Lu JF et al (1994) The MOS 36-item short-form health survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care 32(1):40–66CrossRefPubMed McHorney CA, Ware JE, Lu JF et al (1994) The MOS 36-item short-form health survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care 32(1):40–66CrossRefPubMed
15.
go back to reference Beck AT, Ward CH, Mendelson M et al (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571CrossRefPubMed Beck AT, Ward CH, Mendelson M et al (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571CrossRefPubMed
Metadata
Title
Renal hilar block predicts long-term success of renal auto-transplantation for loin pain hematuria syndrome
Authors
Jeffrey Campsen
Mitchell R. Bassett
Ryan O’Hara
Robin D. Kim
Eryberto Martinez
Rulon Hardman
Jeremy B. Myers
Blake Hamilton
Publication date
01-06-2019
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 6/2019
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-019-02143-z

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