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01-03-2018 | Nephrology - Review

Iron in kidney and heart failure: from theory to practice

Authors: Aslihan Yerlikaya, Mustafa C. Bulbul, Baris Afsar, Tuncay Dagel, Gamze Aslan, Luminita Voroneanu, Dimitire Siriopol, Adrian Covic, Mehmet Kanbay

Published in: International Urology and Nephrology | Issue 3/2018

Abstract

There is evidence that serum iron levels, regardless of the presence of anemia, directly impact outcomes in congestive heart failure (CHF) including quality of life, hospitalization rate and overall survival. Despite modern medical treatments, the prognosis of CHF remains grim. Ironically, simple iron replenishment may serve as a powerful tool in the armamentarium. This review will start from fundamental concepts of iron in oxygen delivery and analyze evidence-based outcomes in CHF iron-directed therapeutic trials. Imaging rationale that dovetails with this pathophysiology will also be detailed in a clinician-directed fashion.

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Title: Iron in kidney and heart failure: from theory to practice
Authors: Aslihan Yerlikaya
Mustafa C. Bulbul
Baris Afsar
Tuncay Dagel
Gamze Aslan
Luminita Voroneanu
Dimitire Siriopol
Adrian Covic
Mehmet Kanbay
Publication date: 01-03-2018
Publisher: Springer Netherlands
Published in: International Urology and Nephrology / Issue 3/2018
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI: https://doi.org/10.1007/s11255-017-1708-6

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