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Published in: International Urology and Nephrology 11/2016

01-11-2016 | Nephrology - Original Paper

Pre-dialysis renal clinic visits and patients’ outcomes on peritoneal dialysis

Authors: Wen Tang, Xiu-Hong Hu, Lei Zhu, Zhe-Li Niu, Chu-Yan Su, Qing-Feng Han, Tao Wang

Published in: International Urology and Nephrology | Issue 11/2016

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Abstract

Purpose

To investigate the effect of pre-dialysis renal care on peritoneal dialysis (PD) patients’ outcomes in China.

Methods

In this retrospective cohort study, patients who started PD during January 1, 2006, to December 31, 2014, were included. Patients’ medical charts were reviewed to extract the information. To explore the effect of pre-dialysis renal care on patients’ outcomes, patient were divided into two groups according to whether or not they had frequent renal clinic visits: Group A (with frequent visits) and Group B (without frequent visits).

Results

A total of 668 patients were included. Patients who admitted to emergency room before PD initiations were significantly higher in Group B than in Group A (42.7 vs. 33 %, p = 0.01). However, there was no significant difference in the proportion of patients requiring emergency hemodialysis prior to PD commencement (20.5 vs. 24.6 %, p = 0.21), acute heart failure (30.2 vs. 35.4 %, p = 0.16) and pulmonary infection (15.4 vs. 12.1 %, p = 0.23) between groups. Both the mortality and technical failure rate in Group A were significantly lower as compared to Group B (p = 0.003 and p < 0.01, respectively). Multivariable Cox regression analysis showed frequent pre-dialysis renal clinic visits were associated with both lower mortality rate (HR 0.62, 95 % CI 0.46–0.85, p = 0.003) and technical failure on PD (HR 0.58, 95 % CI 0.36–0.92, p = 0.022).

Conclusion

Pre-dialysis frequent clinic visits were associated with better PD outcomes. Pre-dialysis renal clinic management was suboptimal in the present cohort. More organized system to ensure people with established chronic kidney disease are well managed is necessary in China.
Literature
1.
go back to reference Baer G, Lameire N, Van Biesen W (2010) Late referral of patients with end-stage renal disease: an in-depth review and suggestions for further actions. NDT Plus 3(1):17–27. doi:10.1093/ndtplus/sfp050 PubMed Baer G, Lameire N, Van Biesen W (2010) Late referral of patients with end-stage renal disease: an in-depth review and suggestions for further actions. NDT Plus 3(1):17–27. doi:10.​1093/​ndtplus/​sfp050 PubMed
2.
go back to reference Bello AK, Levin A, Manns BJ, Feehally J, Drueke T, Faruque L, Hemmelgarn BR, Kernahan C, Mann J, Klarenbach S, Remuzzi G, Tonelli M, Kidney Health for Life I (2015) Effective CKD care in European countries: challenges and opportunities for health policy. Am J Kidney Dis 65(1):15–25. doi:10.1053/j.ajkd.2014.07.033 CrossRefPubMed Bello AK, Levin A, Manns BJ, Feehally J, Drueke T, Faruque L, Hemmelgarn BR, Kernahan C, Mann J, Klarenbach S, Remuzzi G, Tonelli M, Kidney Health for Life I (2015) Effective CKD care in European countries: challenges and opportunities for health policy. Am J Kidney Dis 65(1):15–25. doi:10.​1053/​j.​ajkd.​2014.​07.​033 CrossRefPubMed
4.
go back to reference Zhang L, Wang F, Wang L, Wang W, Liu B, Liu J, Chen M, He Q, Liao Y, Yu X, Chen N, Zhang JE, Hu Z, Liu F, Hong D, Ma L, Liu H, Zhou X, Chen J, Pan L, Chen W, Wang W, Li X, Wang H (2012) Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet 379(9818):815–822. doi:10.1016/S0140-6736(12)60033-6 CrossRefPubMed Zhang L, Wang F, Wang L, Wang W, Liu B, Liu J, Chen M, He Q, Liao Y, Yu X, Chen N, Zhang JE, Hu Z, Liu F, Hong D, Ma L, Liu H, Zhou X, Chen J, Pan L, Chen W, Wang W, Li X, Wang H (2012) Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet 379(9818):815–822. doi:10.​1016/​S0140-6736(12)60033-6 CrossRefPubMed
7.
go back to reference Mendelssohn DC, Curtis B, Yeates K, Langlois S, MacRae JM, Semeniuk LM, Camacho F, McFarlane P, Investigators SS (2011) Suboptimal initiation of dialysis with and without early referral to a nephrologist. Nephrol Dial Transplant 26(9):2959–2965. doi:10.1093/ndt/gfq843 CrossRefPubMed Mendelssohn DC, Curtis B, Yeates K, Langlois S, MacRae JM, Semeniuk LM, Camacho F, McFarlane P, Investigators SS (2011) Suboptimal initiation of dialysis with and without early referral to a nephrologist. Nephrol Dial Transplant 26(9):2959–2965. doi:10.​1093/​ndt/​gfq843 CrossRefPubMed
9.
go back to reference Goransson LG, Bergrem H (2001) Consequences of late referral of patients with end-stage renal disease. J Intern Med 250(2):154–159CrossRefPubMed Goransson LG, Bergrem H (2001) Consequences of late referral of patients with end-stage renal disease. J Intern Med 250(2):154–159CrossRefPubMed
10.
go back to reference Chow KM, Szeto CC, Law MC, Kwan BC, Leung CB, Li PK (2008) Impact of early nephrology referral on mortality and hospitalization in peritoneal dialysis patients. Perit dial int J Int Soc Perit Dial 28(4):371–376 Chow KM, Szeto CC, Law MC, Kwan BC, Leung CB, Li PK (2008) Impact of early nephrology referral on mortality and hospitalization in peritoneal dialysis patients. Perit dial int J Int Soc Perit Dial 28(4):371–376
11.
go back to reference Wu MS, Lin CL, Chang CT, Wu CH, Huang JY, Yang CW (2003) Improvement in clinical outcome by early nephrology referral in type II diabetics on maintenance peritoneal dialysis. Perit dialysis int J Int Soc Perit Dial 23(1):39–45 Wu MS, Lin CL, Chang CT, Wu CH, Huang JY, Yang CW (2003) Improvement in clinical outcome by early nephrology referral in type II diabetics on maintenance peritoneal dialysis. Perit dialysis int J Int Soc Perit Dial 23(1):39–45
12.
go back to reference Lin CL, Chuang FR, Wu CF, Yang CT (2004) Early referral as an independent predictor of clinical outcome in end-stage renal disease on hemodialysis and continuous ambulatory peritoneal dialysis. Ren Fail 26(5):531–537CrossRefPubMed Lin CL, Chuang FR, Wu CF, Yang CT (2004) Early referral as an independent predictor of clinical outcome in end-stage renal disease on hemodialysis and continuous ambulatory peritoneal dialysis. Ren Fail 26(5):531–537CrossRefPubMed
13.
go back to reference Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, Coresh J, Ckd-EPI (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150(9):604–612CrossRefPubMedPubMedCentral Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, Coresh J, Ckd-EPI (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150(9):604–612CrossRefPubMedPubMedCentral
15.
go back to reference Hughes SA, Mendelssohn JG, Tobe SW, McFarlane PA, Mendelssohn DC (2013) Factors associated with suboptimal initiation of dialysis despite early nephrologist referral. Nephrol Dial Transplant 28(2):392–397. doi:10.1093/ndt/gfs431 CrossRefPubMed Hughes SA, Mendelssohn JG, Tobe SW, McFarlane PA, Mendelssohn DC (2013) Factors associated with suboptimal initiation of dialysis despite early nephrologist referral. Nephrol Dial Transplant 28(2):392–397. doi:10.​1093/​ndt/​gfs431 CrossRefPubMed
16.
go back to reference Titze S, Schmid M, Kottgen A, Busch M, Floege J, Wanner C, Kronenberg F, Eckardt KU, Investigators Gs (2015) Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. Nephrol Dial Transplant 30(3):441–451. doi:10.1093/ndt/gfu294 CrossRefPubMed Titze S, Schmid M, Kottgen A, Busch M, Floege J, Wanner C, Kronenberg F, Eckardt KU, Investigators Gs (2015) Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. Nephrol Dial Transplant 30(3):441–451. doi:10.​1093/​ndt/​gfu294 CrossRefPubMed
17.
go back to reference Levin A, Lewis M, Mortiboy P, Faber S, Hare I, Porter EC, Mendelssohn DC (1997) Multidisciplinary predialysis programs: quantification and limitations of their impact on patient outcomes in two Canadian settings. Am J Kidney Dis 29(4):533–540CrossRefPubMed Levin A, Lewis M, Mortiboy P, Faber S, Hare I, Porter EC, Mendelssohn DC (1997) Multidisciplinary predialysis programs: quantification and limitations of their impact on patient outcomes in two Canadian settings. Am J Kidney Dis 29(4):533–540CrossRefPubMed
18.
go back to reference Goldstein M, Yassa T, Dacouris N, McFarlane P (2004) Multidisciplinary predialysis care and morbidity and mortality of patients on dialysis. Am J Kidney Dis 44(4):706–714CrossRefPubMed Goldstein M, Yassa T, Dacouris N, McFarlane P (2004) Multidisciplinary predialysis care and morbidity and mortality of patients on dialysis. Am J Kidney Dis 44(4):706–714CrossRefPubMed
Metadata
Title
Pre-dialysis renal clinic visits and patients’ outcomes on peritoneal dialysis
Authors
Wen Tang
Xiu-Hong Hu
Lei Zhu
Zhe-Li Niu
Chu-Yan Su
Qing-Feng Han
Tao Wang
Publication date
01-11-2016
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 11/2016
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-016-1400-2

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