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01-06-2016 | Nephrology – Review

Clinical imaging of vascular disease in chronic kidney disease

Authors: Alan A. Sag, Adrian Covic, Gerard London, Marc Vervloet, David Goldsmith, Jose Luis Gorriz, Mehmet Kanbay

Published in: International Urology and Nephrology | Issue 6/2016

Abstract

Arterial wall calcification, once considered an incidental finding, is now known to be a consistent and strong predictor of cardiovascular events in patients with chronic renal insufficiency. It is also commonly encountered in radiologic examinations as an incidental finding. Forthcoming bench, translational, and clinical data seek to establish this and pre-calcification changes as surrogate imaging biomarkers for noninvasive prognostication and treatment follow-up. Emerging paradigms seek to establish vascular calcification as a surrogate marker of disease. Imaging of pre-calcification and decalcification events may prove more important than imaging of the calcification itself. Data-driven approaches to screening will be necessary to limit radiation exposure and prevent over-utilization of expensive imaging techniques.

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Title: Clinical imaging of vascular disease in chronic kidney disease
Authors: Alan A. Sag
Adrian Covic
Gerard London
Marc Vervloet
David Goldsmith
Jose Luis Gorriz
Mehmet Kanbay
Publication date: 01-06-2016
Publisher: Springer Netherlands
Published in: International Urology and Nephrology / Issue 6/2016
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI: https://doi.org/10.1007/s11255-016-1240-0

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