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International Urology and Nephrology
Published in: International Urology and Nephrology 2/2012

01-04-2012 | Nephrology – Case Report

Systemic mastocytosis presenting with acute oliguric renal failure: report of a case and review of the literature

Authors: Ann E. Moore, William H. Johnston, Aviv Hever, Susy Peng, Dean A. Kujubu

Published in: International Urology and Nephrology | Issue 2/2012

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Abstract

A 61-year old African-American woman presented with abdominal pain, tender splenomegaly, anemia, and renal insufficiency. Bone marrow biopsy demonstrated systemic mastocytosis. She was treated with mediator-specific therapy and imatinib, but her renal and hepatic function deteriorated and she required maintenance hemodialysis. Renal biopsy demonstrated interstitial infiltration with mast cells and acute tubular necrosis. Acute kidney injury in the setting of systemic mastocytosis and imatinib therapy is discussed.
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Metadata
Title
Systemic mastocytosis presenting with acute oliguric renal failure: report of a case and review of the literature
Authors
Ann E. Moore
William H. Johnston
Aviv Hever
Susy Peng
Dean A. Kujubu
Publication date
01-04-2012
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 2/2012
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-010-9878-5

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