Published in:
Open Access
01-01-2016
Pharmacology of anticoagulants used in the treatment of venous thromboembolism
Authors:
Edith A. Nutescu, Allison Burnett, John Fanikos, Sarah Spinler, Ann Wittkowsky
Published in:
Journal of Thrombosis and Thrombolysis
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Issue 1/2016
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Abstract
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects. Thus, anticoagulant therapy selection should be guided by the risks, benefits and pharmacologic characteristics of each agent for each patient. Safe use of anticoagulants requires not only an in-depth knowledge of their pharmacologic properties but also a comprehensive approach to patient management and education. This paper will summarize the key pharmacologic properties of the anticoagulant agents used in the treatment of patients with VTE.