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Journal of Thrombosis and Thrombolysis
Published in: Journal of Thrombosis and Thrombolysis 3/2014

01-04-2014

Pulmonary embolism in pregnancy

Authors: E. Conti, L. Zezza, E. Ralli, C. Comito, L. Sada, J. Passerini, D. Caserta, S. Rubattu, C. Autore, M. Moscarini, M. Volpe

Published in: Journal of Thrombosis and Thrombolysis | Issue 3/2014

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Abstract

Venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality during pregnancy or early after delivery, remaining a diagnostic and therapeutic challenge in both states. The absolute incidence of pregnancy-associated VTE has been reported as 1 in 1,000 to 1 in 2,000 deliveries. With 5–6 million new births computed in Europe in 2010, the potential clinical relevance of diagnosing and treating gravidic VTE is immediately evident. Fivefold higher in a pregnant as compared with a non-pregnant woman, VTE risk is also higher in postpartum than antepartum period. Ranked absolute and relative thrombotic risk may be described in the several thrombophilic conditions experienced by women at risk, according to which specific prophylactic and therapeutic recommendations have been formulated by recent guidelines. The main purpose of the present review article was to emphasize the most recent findings and recommendations in diagnostic strategies, discussing thrombophilic risk evaluation, as well as risks and benefits of various diagnostic techniques for both mother and fetus.
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Metadata
Title
Pulmonary embolism in pregnancy
Authors
E. Conti
L. Zezza
E. Ralli
C. Comito
L. Sada
J. Passerini
D. Caserta
S. Rubattu
C. Autore
M. Moscarini
M. Volpe
Publication date
01-04-2014
Publisher
Springer US
Published in
Journal of Thrombosis and Thrombolysis / Issue 3/2014
Print ISSN: 0929-5305
Electronic ISSN: 1573-742X
DOI
https://doi.org/10.1007/s11239-013-0941-9

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