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Reviews in Endocrine and Metabolic Disorders
Published in: Reviews in Endocrine and Metabolic Disorders 3/2016

01-09-2016

Skin steroidogenesis in health and disease

Authors: Georgios Nikolakis, Constantine A. Stratakis, Theodora Kanaki, Andrej Slominski, Christos C. Zouboulis

Published in: Reviews in Endocrine and Metabolic Disorders | Issue 3/2016

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Abstract

The skin is an important extra-gonadal steroidogenic organ, capable of metabolizing various hormones from their precursors, as well as of synthesizing de novo a broad palette of sex steroids and glucocorticoids from cholesterol. In this manuscript, we review the major steroidogenic properties of human skin and we suggest steroidogenesis’ impairment as a cardinal factor for various pathological conditions such as acne, rosacea, atopic dermatitis, and androgenic alopecia.
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Metadata
Title
Skin steroidogenesis in health and disease
Authors
Georgios Nikolakis
Constantine A. Stratakis
Theodora Kanaki
Andrej Slominski
Christos C. Zouboulis
Publication date
01-09-2016
Publisher
Springer US
Published in
Reviews in Endocrine and Metabolic Disorders / Issue 3/2016
Print ISSN: 1389-9155
Electronic ISSN: 1573-2606
DOI
https://doi.org/10.1007/s11154-016-9390-z

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