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Reviews in Endocrine and Metabolic Disorders
Published in: Reviews in Endocrine and Metabolic Disorders 1/2010

01-03-2010

Endothelial dysfunction in diabetes mellitus: Molecular mechanisms and clinical implications

Authors: Corey E. Tabit, William B. Chung, Naomi M. Hamburg, Joseph A. Vita

Published in: Reviews in Endocrine and Metabolic Disorders | Issue 1/2010

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Abstract

Cardiovascular disease is a major complication of diabetes mellitus, and improved strategies for prevention and treatment are needed. Endothelial dysfunction contributes to the pathogenesis and clinical expression of atherosclerosis in diabetes mellitus. This article reviews the evidence linking endothelial dysfunction to human diabetes mellitus and experimental studies that investigated the responsible mechanisms. We then discuss the implications of these studies for current management and for new approaches for the prevention and treatment of cardiovascular disease in patients with diabetes mellitus.
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Metadata
Title
Endothelial dysfunction in diabetes mellitus: Molecular mechanisms and clinical implications
Authors
Corey E. Tabit
William B. Chung
Naomi M. Hamburg
Joseph A. Vita
Publication date
01-03-2010
Publisher
Springer US
Published in
Reviews in Endocrine and Metabolic Disorders / Issue 1/2010
Print ISSN: 1389-9155
Electronic ISSN: 1573-2606
DOI
https://doi.org/10.1007/s11154-010-9134-4

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