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Pituitary
Published in: Pituitary 3/2013

01-09-2013

Pituitary stem cells: candidates and implications

Authors: Farshad Nassiri, Michael Cusimano, Jeff A. Zuccato, Safraz Mohammed, Fabio Rotondo, Eva Horvath, Luis V. Syro, Kalman Kovacs, Ricardo V. Lloyd

Published in: Pituitary | Issue 3/2013

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Abstract

The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type.
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Metadata
Title
Pituitary stem cells: candidates and implications
Authors
Farshad Nassiri
Michael Cusimano
Jeff A. Zuccato
Safraz Mohammed
Fabio Rotondo
Eva Horvath
Luis V. Syro
Kalman Kovacs
Ricardo V. Lloyd
Publication date
01-09-2013
Publisher
Springer US
Published in
Pituitary / Issue 3/2013
Print ISSN: 1386-341X
Electronic ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-013-0470-8

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