Published in:
01-03-2008 | Case Report
An unusual association of a sellar gangliocytoma with a prolactinoma
Authors:
Omar Serri, France Berthelet, Manon Bélair, Sophie Vallette, Sylvia L. Asa
Published in:
Pituitary
|
Issue 1/2008
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Abstract
The simultaneous occurrence of a hypothalamic and sellar gangliocytoma with a pituitary prolactinoma is very rare. The explanation for such an association is not known. We describe the case of a woman who had a coexisting adjacent pituitary prolactinoma and gangliocytoma within the same sellar mass. The tumor cells of the gangliocytoma demonstrated expression of enkephalin, a product of proopiomelanocortin known to be a prolactin secretagogue. We postulate that in this patient there may be a link between gangliocytoma enkephalin and prolactin hypersecretion.