Skip to main content
Top
Published in: International Journal of Clinical Pharmacy 5/2019

01-10-2019 | Warfarin | Research Article

Pharmacogenomics-based practice in North Cyprus: its adoption by pharmacists and their attitudes and knowledge

Authors: Louai Alsaloumi, Abdikarim Abdi, Özgür Tosun, Bilgen Başgut

Published in: International Journal of Clinical Pharmacy | Issue 5/2019

Login to get access

Abstract

Background Pharmacogenomics is a branch of biotechnological science integrating medicine, pharmacology, and genomics techniques. Moreover, it focuses on creating drug therapies in order to analyze genetic differences in patients causing various responses to a single therapeutic regimen. Objective This cross sectional study aimed to examine the attitude, knowledge and adoption among pharmacists in North Cyprus and the most appropriate method to improve education among them. Setting Community pharmacy setting. Method A total of 103 out of 140 pharmacists responded to a pre-tested and validated questionnaire consisting of 25 items during July through September 2016. Main outcome measure Pharmacists attitude, knowledge and adoption towards pharmacogenomic tests. Result Data showed that most of the pharmacists in North Cyprus had positive attitude and knowledge scores with mean value of 28.3 ± 5.3 (out of 40) and 6.9 ± 0.8 (out of 10) respectively, further findings showed that there is a significant difference among age groups in their total attitude score (p < 0.05). Conclusion Even though pharmacogenomics is a field promising a variety of benefits, it is vital to implement it in clinical settings in order to improve outcomes. Our findings highlight the necessity for more education on the availability and interpretation of pharmacogenomics tests.
Appendix
Available only for authorised users
Literature
1.
go back to reference De Denus S, Letarte N, Hurlimann T, Lambert J-P, Lavoie A, Robb L, et al. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics. 2013;14(2):165–75.PubMedCrossRef De Denus S, Letarte N, Hurlimann T, Lambert J-P, Lavoie A, Robb L, et al. An evaluation of pharmacists’ expectations towards pharmacogenomics. Pharmacogenomics. 2013;14(2):165–75.PubMedCrossRef
2.
go back to reference Mizzi C, Peters B, Mitropoulou C, Mitropoulos K, Katsila T, Agarwal MR, et al. Personalized pharmacogenomics profiling using whole-genome sequencing. Pharmacogenomics. 2014;15(9):1223–34.PubMedCrossRef Mizzi C, Peters B, Mitropoulou C, Mitropoulos K, Katsila T, Agarwal MR, et al. Personalized pharmacogenomics profiling using whole-genome sequencing. Pharmacogenomics. 2014;15(9):1223–34.PubMedCrossRef
3.
go back to reference Salleh MZ, Teh LK, Lee LS, Ismet RI, Patowary A, Joshi K, et al. Systematic pharmacogenomics analysis of a Malay whole genome: proof of concept for personalized medicine. PLoS ONE. 2013;8(8):e71554.PubMedPubMedCentralCrossRef Salleh MZ, Teh LK, Lee LS, Ismet RI, Patowary A, Joshi K, et al. Systematic pharmacogenomics analysis of a Malay whole genome: proof of concept for personalized medicine. PLoS ONE. 2013;8(8):e71554.PubMedPubMedCentralCrossRef
4.
go back to reference Bannur Z, Bahaman S, Salleh M, Kek TL. Pharmacogenomics based practice in Malaysia: the attitude, knowledge and adoption by the healthcare professionals. Int Med J Malays. 2014;13(1):41–50. Bannur Z, Bahaman S, Salleh M, Kek TL. Pharmacogenomics based practice in Malaysia: the attitude, knowledge and adoption by the healthcare professionals. Int Med J Malays. 2014;13(1):41–50.
6.
go back to reference Holmes DR, Dehmer GJ, Kaul S, Leifer D, O’Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA “boxed warning”: a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2010;56(4):321–41.PubMedCrossRef Holmes DR, Dehmer GJ, Kaul S, Leifer D, O’Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA “boxed warning”: a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2010;56(4):321–41.PubMedCrossRef
7.
go back to reference Relling M, Klein T. CPIC: clinical pharmacogenetics implementation consortium of the pharmacogenomics research network. Clin Pharmacol Ther. 2011;89(3):464–7.PubMedPubMedCentralCrossRef Relling M, Klein T. CPIC: clinical pharmacogenetics implementation consortium of the pharmacogenomics research network. Clin Pharmacol Ther. 2011;89(3):464–7.PubMedPubMedCentralCrossRef
8.
go back to reference Wu AH. Use of genetic and nongenetic factors in warfarin dosing algorithms. Pharmacogenomics. 2007;8(7):851–61.PubMedCrossRef Wu AH. Use of genetic and nongenetic factors in warfarin dosing algorithms. Pharmacogenomics. 2007;8(7):851–61.PubMedCrossRef
9.
go back to reference Lesko L, Woodcock J. Pharmacogenomic-guided drug development: regulatory perspective. Pharmacogenomics J. 2002;2(1):20.PubMedCrossRef Lesko L, Woodcock J. Pharmacogenomic-guided drug development: regulatory perspective. Pharmacogenomics J. 2002;2(1):20.PubMedCrossRef
10.
go back to reference Lesko LJ, Woodcock J. Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective. Nat Rev Drug Discov. 2004;3(9):763.PubMedCrossRef Lesko LJ, Woodcock J. Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective. Nat Rev Drug Discov. 2004;3(9):763.PubMedCrossRef
11.
go back to reference Zineh I, Lesko LJ. Pharmacogenetics in medicine: barriers, critical factors and a framework for dialogue. Pers Med. 2009;6(4):359–61.CrossRef Zineh I, Lesko LJ. Pharmacogenetics in medicine: barriers, critical factors and a framework for dialogue. Pers Med. 2009;6(4):359–61.CrossRef
12.
go back to reference Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JP. Life cycle of translational research for medical interventions. Science. 2008;321(5894):1.CrossRef Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JP. Life cycle of translational research for medical interventions. Science. 2008;321(5894):1.CrossRef
13.
go back to reference Crews KR, Hicks JK, Pui CH, Relling MV, Evans WE. Pharmacogenomics and individualized medicine: translating science into practice. Clin Pharmacol Ther. 2012;92(4):467–75.PubMed Crews KR, Hicks JK, Pui CH, Relling MV, Evans WE. Pharmacogenomics and individualized medicine: translating science into practice. Clin Pharmacol Ther. 2012;92(4):467–75.PubMed
14.
15.
go back to reference Maronde RF, Lee PV, McCarron MM, Seibert S. A study of prescribing patterns. Med Care. 1971;9(5):383–95.PubMedCrossRef Maronde RF, Lee PV, McCarron MM, Seibert S. A study of prescribing patterns. Med Care. 1971;9(5):383–95.PubMedCrossRef
16.
go back to reference Kohn LT, Corrigan J, Donaldson MS. To err is human: building a safer health system. Washington, DC: National Academy Press; 2000. Kohn LT, Corrigan J, Donaldson MS. To err is human: building a safer health system. Washington, DC: National Academy Press; 2000.
17.
go back to reference Leape LL, Cullen DJ, Clapp MD, Burdick E, Demonaco HJ, Erickson JI, et al. Pharmacist participation on physician rounds and adverse drug events in the intensive care unit. JAMA. 1999;282(3):267–70.PubMedCrossRef Leape LL, Cullen DJ, Clapp MD, Burdick E, Demonaco HJ, Erickson JI, et al. Pharmacist participation on physician rounds and adverse drug events in the intensive care unit. JAMA. 1999;282(3):267–70.PubMedCrossRef
18.
go back to reference Swen J, Nijenhuis M, Boer AD, Grandia L, Maitland-van der Zee A-H, Mulder H, et al. Pharmacogenetics: from bench to byte—an update of guidelines. Pharmacol Ther. 2011;89(5):662–73.CrossRef Swen J, Nijenhuis M, Boer AD, Grandia L, Maitland-van der Zee A-H, Mulder H, et al. Pharmacogenetics: from bench to byte—an update of guidelines. Pharmacol Ther. 2011;89(5):662–73.CrossRef
19.
go back to reference Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, et al. Implementing genomic medicine in the clinic: the future is here. Genet Med. 2013;15(4):258.PubMedPubMedCentralCrossRef Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, et al. Implementing genomic medicine in the clinic: the future is here. Genet Med. 2013;15(4):258.PubMedPubMedCentralCrossRef
20.
go back to reference Wu A, Fuhlbrigge A. Economic evaluation of pharmacogenetic tests. Clin Pharmacol Ther. 2008;84(2):272–4.PubMedCrossRef Wu A, Fuhlbrigge A. Economic evaluation of pharmacogenetic tests. Clin Pharmacol Ther. 2008;84(2):272–4.PubMedCrossRef
21.
go back to reference Cavallari LH, Lee CR, Duarte JD, Nutescu EA, Weitzel KW, Stouffer GA, et al. Implementation of inpatient models of pharmacogenetics programs. Am J Health Syst Pharm. 2016;73(23):1944–54.PubMedCrossRef Cavallari LH, Lee CR, Duarte JD, Nutescu EA, Weitzel KW, Stouffer GA, et al. Implementation of inpatient models of pharmacogenetics programs. Am J Health Syst Pharm. 2016;73(23):1944–54.PubMedCrossRef
22.
go back to reference Akhtar S. Pharmacogenomics: Are pharmacists ready for genotyped prescribing? Pharm J. 2002;268(7187):296–9. Akhtar S. Pharmacogenomics: Are pharmacists ready for genotyped prescribing? Pharm J. 2002;268(7187):296–9.
23.
go back to reference Haga SB, Moaddeb J, Mills R, Patel M, Kraus W, Allen LaPointe NM. Incorporation of pharmacogenetic testing into medication therapy management. Pharmacogenomics. 2015;16(17):1931–41.PubMedCrossRef Haga SB, Moaddeb J, Mills R, Patel M, Kraus W, Allen LaPointe NM. Incorporation of pharmacogenetic testing into medication therapy management. Pharmacogenomics. 2015;16(17):1931–41.PubMedCrossRef
24.
go back to reference El-Ibiary SY, Cheng C, Alldredge B. Potential roles for pharmacists in pharmacogenetics. J Am Pharm Assoc. 2008;48(2):e21–32.CrossRef El-Ibiary SY, Cheng C, Alldredge B. Potential roles for pharmacists in pharmacogenetics. J Am Pharm Assoc. 2008;48(2):e21–32.CrossRef
25.
go back to reference Ferreri SP, Greco AJ, Michaels NM, O’Connor SK, Chater RW, Viera AJ, et al. Implementation of a pharmacogenomics service in a community pharmacy. J Am Pharm Assoc. 2014;54(2):172–80.CrossRef Ferreri SP, Greco AJ, Michaels NM, O’Connor SK, Chater RW, Viera AJ, et al. Implementation of a pharmacogenomics service in a community pharmacy. J Am Pharm Assoc. 2014;54(2):172–80.CrossRef
26.
go back to reference Bright D, Kisor D, Smith A, Conaway M, Yu M. Implementation of a pharmacogenetic management service for postmyocardial infarction care in a community pharmacy. Pers Med. 2015;12(4):319–25.CrossRef Bright D, Kisor D, Smith A, Conaway M, Yu M. Implementation of a pharmacogenetic management service for postmyocardial infarction care in a community pharmacy. Pers Med. 2015;12(4):319–25.CrossRef
27.
go back to reference Papastergiou J, Tolios P, Li W, Li J. The Innovative Canadian Pharmacogenomic Screening Initiative in Community Pharmacy (ICANPIC) study. J Am Pharm Assoc. 2017;57(5):624–9.CrossRef Papastergiou J, Tolios P, Li W, Li J. The Innovative Canadian Pharmacogenomic Screening Initiative in Community Pharmacy (ICANPIC) study. J Am Pharm Assoc. 2017;57(5):624–9.CrossRef
28.
go back to reference McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract. 2011;9(3):141–7. McMahon T, Tucci J. The perceptions of pharmacists in Victoria, Australia on pharmacogenetics and its implications. Pharm Pract. 2011;9(3):141–7.
29.
go back to reference Dias M, Ward H, Sorich M, McKinnon R. Exploration of the perceptions, barriers and drivers of pharmacogenomics practice among hospital pharmacists in Adelaide, South Australia. Pharmacogenomics J. 2014;14(3):235.PubMedCrossRef Dias M, Ward H, Sorich M, McKinnon R. Exploration of the perceptions, barriers and drivers of pharmacogenomics practice among hospital pharmacists in Adelaide, South Australia. Pharmacogenomics J. 2014;14(3):235.PubMedCrossRef
30.
go back to reference Dodson C. Knowledge and attitudes concerning pharmacogenomics among healthcare professionals. Pers Med. 2011;8(4):421–8.CrossRef Dodson C. Knowledge and attitudes concerning pharmacogenomics among healthcare professionals. Pers Med. 2011;8(4):421–8.CrossRef
31.
go back to reference Clemerson JP, Payne K, Bissell P, Anderson C. Pharmacogenetics, the next challenge for pharmacy? Pharm World Sci. 2006;28(3):126.PubMedCrossRef Clemerson JP, Payne K, Bissell P, Anderson C. Pharmacogenetics, the next challenge for pharmacy? Pharm World Sci. 2006;28(3):126.PubMedCrossRef
32.
go back to reference Ma JD, Lee KC, Kuo GM. Clinical application of pharmacogenomics. J Pharm Pract. 2012;25(4):417–27.PubMedCrossRef Ma JD, Lee KC, Kuo GM. Clinical application of pharmacogenomics. J Pharm Pract. 2012;25(4):417–27.PubMedCrossRef
33.
go back to reference Ventola CL. The role of pharmacogenomic biomarkers in predicting and improving drug response: part 2: challenges impeding clinical implementation. Pharm Ther. 2013;38(10):624. Ventola CL. The role of pharmacogenomic biomarkers in predicting and improving drug response: part 2: challenges impeding clinical implementation. Pharm Ther. 2013;38(10):624.
34.
go back to reference Yau A, Aziz AB, Haque M. Knowledge, attitude and practice concerning pharmacogenomics among pharmacists: a systematic review. J Young Pharm. 2015;7(3):145.CrossRef Yau A, Aziz AB, Haque M. Knowledge, attitude and practice concerning pharmacogenomics among pharmacists: a systematic review. J Young Pharm. 2015;7(3):145.CrossRef
35.
go back to reference Abdi AM, Zarouri AT, Saloumi L, Basgut B. North Cyprus pharmacist’s cognition and practice of pharmaceutical care. J Pharm Res Int. 2018;21(3):9.CrossRef Abdi AM, Zarouri AT, Saloumi L, Basgut B. North Cyprus pharmacist’s cognition and practice of pharmaceutical care. J Pharm Res Int. 2018;21(3):9.CrossRef
36.
go back to reference Al-Baghdadi H, Al-Baghdadi ÇK, Abdi A, Gültekin O, Meštrović A, Demirdamar R, et al. Introducing clinical pharmacy services to cardiovascular clinics at a university hospital in Northern Cyprus. Int J Clin Pharm. 2017;39(6):8.CrossRef Al-Baghdadi H, Al-Baghdadi ÇK, Abdi A, Gültekin O, Meštrović A, Demirdamar R, et al. Introducing clinical pharmacy services to cardiovascular clinics at a university hospital in Northern Cyprus. Int J Clin Pharm. 2017;39(6):8.CrossRef
37.
go back to reference Gökçekuş L, Mestrovic A, Basgut B. Pharmacist intervention in drug-related problems for patients with cardiovascular diseases in selected community pharmacies in Northern Cyprus. Trop J Pharm Res. 2016;15(10):2275–81.CrossRef Gökçekuş L, Mestrovic A, Basgut B. Pharmacist intervention in drug-related problems for patients with cardiovascular diseases in selected community pharmacies in Northern Cyprus. Trop J Pharm Res. 2016;15(10):2275–81.CrossRef
38.
go back to reference Arsoy G, Varış A, Saloumi L, Abdi A, Başgut B. Insights on allergic rhinitis management from a Northern Cyprus perspective and evaluation of the impact of pharmacist-led educational intervention on patients’ outcomes. Medicina. 2018;5(54):83.CrossRef Arsoy G, Varış A, Saloumi L, Abdi A, Başgut B. Insights on allergic rhinitis management from a Northern Cyprus perspective and evaluation of the impact of pharmacist-led educational intervention on patients’ outcomes. Medicina. 2018;5(54):83.CrossRef
39.
go back to reference Pisanu C, Tsermpini E-E, Mavroidi E, Katsila T, Patrinos GP, Squassina A. Assessment of the pharmacogenomics educational environment in Southeast Europe. Public Health Genom. 2014;17(5–6):272–9.CrossRef Pisanu C, Tsermpini E-E, Mavroidi E, Katsila T, Patrinos GP, Squassina A. Assessment of the pharmacogenomics educational environment in Southeast Europe. Public Health Genom. 2014;17(5–6):272–9.CrossRef
40.
go back to reference Saydam F, Değirmenci İ, Birdane A, Özdemir M, Ulus T, Özbayer C, et al. The CYP2C19* 2 and CYP2C19* 17 polymorphisms play a vital role in clopidogrel responsiveness after percutaneous coronary intervention: a pharmacogenomics study. Basic Clin Pharmacol Toxicol. 2017;121(1):29–36.PubMedCrossRef Saydam F, Değirmenci İ, Birdane A, Özdemir M, Ulus T, Özbayer C, et al. The CYP2C19* 2 and CYP2C19* 17 polymorphisms play a vital role in clopidogrel responsiveness after percutaneous coronary intervention: a pharmacogenomics study. Basic Clin Pharmacol Toxicol. 2017;121(1):29–36.PubMedCrossRef
41.
go back to reference Karaca S, Bozkurt NC, Cesuroglu T, Karaca M, Bozkurt M, Eskioglu E, et al. International warfarin genotype-guided dosing algorithms in the Turkish population and their preventive effects on major and life-threatening hemorrhagic events. Pharmacogenomics. 2015;16(10):1109–18.PubMedCrossRef Karaca S, Bozkurt NC, Cesuroglu T, Karaca M, Bozkurt M, Eskioglu E, et al. International warfarin genotype-guided dosing algorithms in the Turkish population and their preventive effects on major and life-threatening hemorrhagic events. Pharmacogenomics. 2015;16(10):1109–18.PubMedCrossRef
42.
go back to reference Eryılmaz G, Hızlı Sayar G, Gül IG, Noyan CO, Özten E, Darçın AE, et al. Therapeutic drug monitoring: perspectives of psychiatrists in Turkey. Int J Psychiatry Clin Pract. 2015;19(1):60–4.PubMedCrossRef Eryılmaz G, Hızlı Sayar G, Gül IG, Noyan CO, Özten E, Darçın AE, et al. Therapeutic drug monitoring: perspectives of psychiatrists in Turkey. Int J Psychiatry Clin Pract. 2015;19(1):60–4.PubMedCrossRef
43.
go back to reference Woelderink A, Ibarreta D, Hopkins M, Rodriguez-Cerezo E. The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies. Pharmacogenomics J. 2006;6(1):3.PubMedCrossRef Woelderink A, Ibarreta D, Hopkins M, Rodriguez-Cerezo E. The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies. Pharmacogenomics J. 2006;6(1):3.PubMedCrossRef
44.
go back to reference Keskin O, Uluca Ü, Birben E, Coşkun Y, Ozkars MY, Keskin M, et al. Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation. Pediatr Allergy Immunol. 2016;27(5):507–13.PubMedCrossRef Keskin O, Uluca Ü, Birben E, Coşkun Y, Ozkars MY, Keskin M, et al. Genetic associations of the response to inhaled corticosteroids in children during an asthma exacerbation. Pediatr Allergy Immunol. 2016;27(5):507–13.PubMedCrossRef
45.
go back to reference Hyzel C, Gok S, Sardas S, Bernard-Gallon D, Maugard C, Genç E. Personalized and predictive medicine in Turkey: a symposium report of the Istanbul Working Group on personalized medicine, Istanbul, Turkey, September 10–12, 2009. Curr Pharmacogenomics Person Med. 2009;7(4):297–301.CrossRef Hyzel C, Gok S, Sardas S, Bernard-Gallon D, Maugard C, Genç E. Personalized and predictive medicine in Turkey: a symposium report of the Istanbul Working Group on personalized medicine, Istanbul, Turkey, September 10–12, 2009. Curr Pharmacogenomics Person Med. 2009;7(4):297–301.CrossRef
46.
go back to reference Ergoren MC, Pirzada RH, Arici M, Serakinci N. Near East University Genetic Mutation Database (NEU-GD): the first mutation database of Northern Cyprus. Gene. 2015;571(1):145–8.PubMedCrossRef Ergoren MC, Pirzada RH, Arici M, Serakinci N. Near East University Genetic Mutation Database (NEU-GD): the first mutation database of Northern Cyprus. Gene. 2015;571(1):145–8.PubMedCrossRef
47.
go back to reference Bisgin A, Kurtaran B, Yasar HM, Tasova Y. Clinical utility of pharmacogenetic testing: current evidence of HLA-B57 positivity. Erciyes Med J. 2017;39(2):S78.CrossRef Bisgin A, Kurtaran B, Yasar HM, Tasova Y. Clinical utility of pharmacogenetic testing: current evidence of HLA-B57 positivity. Erciyes Med J. 2017;39(2):S78.CrossRef
48.
go back to reference Cronbach LJ, Shavelson RJ. My current thoughts on coefficient alpha and successor procedures. Educ Psychol Meas. 2004;64(3):391–418.CrossRef Cronbach LJ, Shavelson RJ. My current thoughts on coefficient alpha and successor procedures. Educ Psychol Meas. 2004;64(3):391–418.CrossRef
50.
go back to reference Hoop JG, Lapid MI, Paulson RM, Roberts LW. Clinical and ethical considerations in pharmacogenetic testing: views of physicians in 3 “early adopting” departments of psychiatry. J Clin Psychiatry. 2010;71(6):745–53.PubMedCrossRef Hoop JG, Lapid MI, Paulson RM, Roberts LW. Clinical and ethical considerations in pharmacogenetic testing: views of physicians in 3 “early adopting” departments of psychiatry. J Clin Psychiatry. 2010;71(6):745–53.PubMedCrossRef
51.
go back to reference Hedgecoe AM. Context, ethics and pharmacogenetics. Stud Hist Philos Biol Biomed Sci. 2006;37(3):566–82.PubMedCrossRef Hedgecoe AM. Context, ethics and pharmacogenetics. Stud Hist Philos Biol Biomed Sci. 2006;37(3):566–82.PubMedCrossRef
52.
go back to reference Kimmel SE, French B, Kasner SE, Johnson JA, Anderson JL, Gage BF, et al. A pharmacogenetic versus a clinical algorithm for warfarin dosing. N Engl J Med. 2013;369(24):2283–93.PubMedPubMedCentralCrossRef Kimmel SE, French B, Kasner SE, Johnson JA, Anderson JL, Gage BF, et al. A pharmacogenetic versus a clinical algorithm for warfarin dosing. N Engl J Med. 2013;369(24):2283–93.PubMedPubMedCentralCrossRef
53.
go back to reference Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Pers Med. 2012;9(1):19–27.CrossRef Roederer MW, Van Riper M, Valgus J, Knafl G, McLeod H. Knowledge, attitudes and education of pharmacists regarding pharmacogenetic testing. Pers Med. 2012;9(1):19–27.CrossRef
54.
go back to reference Remsberg CM, Bray BS, Wright SK, Ashmore J, Kabasenche W, Wang S, et al. Design, implementation, and assessment approaches within a pharmacogenomics course. Am J Pharm Educ. 2017;81(1):11.PubMedPubMedCentral Remsberg CM, Bray BS, Wright SK, Ashmore J, Kabasenche W, Wang S, et al. Design, implementation, and assessment approaches within a pharmacogenomics course. Am J Pharm Educ. 2017;81(1):11.PubMedPubMedCentral
55.
go back to reference Murphy JE, Green JS, Adams LA, Squire RB, Kuo GM, McKay A. Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States. Am J Pharm Educ. 2010;74(1):7.PubMedPubMedCentralCrossRef Murphy JE, Green JS, Adams LA, Squire RB, Kuo GM, McKay A. Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States. Am J Pharm Educ. 2010;74(1):7.PubMedPubMedCentralCrossRef
56.
go back to reference Formea CM, Nicholson WT, McCullough KB, Berg KD, Berg ML, Cunningham JL, et al. Development and evaluation of a pharmacogenomics educational program for pharmacists. Am J Pharm Educ. 2013;77(1):10.PubMedPubMedCentralCrossRef Formea CM, Nicholson WT, McCullough KB, Berg KD, Berg ML, Cunningham JL, et al. Development and evaluation of a pharmacogenomics educational program for pharmacists. Am J Pharm Educ. 2013;77(1):10.PubMedPubMedCentralCrossRef
Metadata
Title
Pharmacogenomics-based practice in North Cyprus: its adoption by pharmacists and their attitudes and knowledge
Authors
Louai Alsaloumi
Abdikarim Abdi
Özgür Tosun
Bilgen Başgut
Publication date
01-10-2019
Publisher
Springer International Publishing
Keyword
Warfarin
Published in
International Journal of Clinical Pharmacy / Issue 5/2019
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-019-00868-6

Other articles of this Issue 5/2019

International Journal of Clinical Pharmacy 5/2019 Go to the issue