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Published in: International Journal of Clinical Pharmacy 5/2014

01-10-2014 | Research Article

Falls prevention focused medication review by a pharmacist in an acute hospital: implications for future practice

Authors: Claire Browne, Claire Kingston, Claire Keane

Published in: International Journal of Clinical Pharmacy | Issue 5/2014

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Abstract

Background Patients at risk of falling are regularly prescribed medicines which increase falls risk. Medication review is a widely advocated risk reduction strategy. Objective The objectives of this descriptive study were to determine the number and types of falls risk medicines suitable for intervention, and to develop guidance to optimise the effectiveness of future medication related falls prevention initiatives. Setting An Irish acute teaching hospital and tertiary referral centre. Method 50 hospital in-patients at risk of falls underwent medication review focused on falls prevention by a pharmacist. Falls risk medicines were identified, and reviewed. If scope to discontinue, dose reduce or switch to a safer alternative was identified by the pharmacist, the suggested medication changes were communicated to the patient’s care team. Main outcome measure Identification of the classes of falls risk medicines and types of prescriptions with greatest potential for intervention. Results The mean number of falls risk medicines prescribed to each patient was 4.8 (±2.8) and the total number prescribed to the 50 patients was 238. Following medication review, the pharmacist identified 48 (20 %) as suitable for intervention. Consequently, 34 medication changes (70.8 %) were implemented. Four medication classes accounted for over 80 % of medication changes. These were anti-emetics, opioid analgesics, anti-cholinergic agents acting on the bladder and benzodiazepines/hypnotics. Intervention was statistically significantly more likely to be possible in the case of p.r.n. medicines compared to regular medicines (p < 0.001, Chi square test). Medication reviews focused on falls prevention took an average of 23.5 min per patient to complete. Conclusion Medication reviews focused on falls prevention involve striking a balance between minimising medicines associated with falls and effectively treating medical conditions. We found only 20 % of falls risk medicines were suitable for change, and reviews were time consuming and resource intensive. However, targeting four medication classes, and being particularly alert to the potential to discontinue ‘as required’ medicines, has the potential to achieve most of the benefits of more comprehensive reviews. This information will guide the development of future falls risk medicine review initiatives in our hospital, increasing their feasibility in the acute hospital setting.
Literature
2.
go back to reference Cameron ID, Murray GR, Gillespie LD, Robertson MC, Hill KD, Cumming RG, et al. Interventions for preventing falls in older people in nursing care facilities and hospitals. Cochrane Database Syst Rev. 2010;(1):CD005465.PubMed Cameron ID, Murray GR, Gillespie LD, Robertson MC, Hill KD, Cumming RG, et al. Interventions for preventing falls in older people in nursing care facilities and hospitals. Cochrane Database Syst Rev. 2010;(1):CD005465.PubMed
3.
go back to reference Healey F, Monro A, Cockram A, Adams V, Heseltine D. Using targeted risk factor reduction to prevent falls in older in-patients: a randomised controlled trial. Age Ageing. 2004;33(4):390–5.PubMedCrossRef Healey F, Monro A, Cockram A, Adams V, Heseltine D. Using targeted risk factor reduction to prevent falls in older in-patients: a randomised controlled trial. Age Ageing. 2004;33(4):390–5.PubMedCrossRef
4.
go back to reference Joint Commission International. Joint commission international accreditation standards for hospitals 4th edition effective from 01/01/2011. USA. 2010. ISBN: 978-1-59940-434-9. Joint Commission International. Joint commission international accreditation standards for hospitals 4th edition effective from 01/01/2011. USA. 2010. ISBN: 978-1-59940-434-9.
5.
go back to reference Oliver D, Britton M, Seed P, Martin FC, Hopper AH. Development and evaluation of evidence based risk assessment tool (STRATIFY) to predict which elderly inpatients will fall: case–control and cohort studies. BMJ. 1997;315:1049–53.PubMedCrossRefPubMedCentral Oliver D, Britton M, Seed P, Martin FC, Hopper AH. Development and evaluation of evidence based risk assessment tool (STRATIFY) to predict which elderly inpatients will fall: case–control and cohort studies. BMJ. 1997;315:1049–53.PubMedCrossRefPubMedCentral
6.
go back to reference Bongue B, Laroche ML, Gutton S, Colvez A, Gueguen R, Moulin JJ, et al. Potentially inappropriate drug prescription in the elderly in France: a population-based study from the French National Insurance Healthcare system. Eur J Clin Pharmacol. 2011;67(12):1291–9.PubMedCrossRef Bongue B, Laroche ML, Gutton S, Colvez A, Gueguen R, Moulin JJ, et al. Potentially inappropriate drug prescription in the elderly in France: a population-based study from the French National Insurance Healthcare system. Eur J Clin Pharmacol. 2011;67(12):1291–9.PubMedCrossRef
8.
go back to reference Dalleur O, Deliens C, Losseau C, Spinewire A, Boland B. Inappropriate Prescriptions according to STOPP and related hospital admission in geriatric patients. Int J Clin Pharm. 2011;33(4):707. Dalleur O, Deliens C, Losseau C, Spinewire A, Boland B. Inappropriate Prescriptions according to STOPP and related hospital admission in geriatric patients. Int J Clin Pharm. 2011;33(4):707.
9.
go back to reference Egger SS, Bachmann A, Hubmann N, Schlienger RG, Krahenbuhl S. Prevalence of potentially inappropriate medication use in elderly patients: comparison between general medical and geriatric wards. Drugs Aging. 2006;23(10):823–37.PubMedCrossRef Egger SS, Bachmann A, Hubmann N, Schlienger RG, Krahenbuhl S. Prevalence of potentially inappropriate medication use in elderly patients: comparison between general medical and geriatric wards. Drugs Aging. 2006;23(10):823–37.PubMedCrossRef
10.
go back to reference Gallagher P, O’Mahony D. STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers’ criteria. Age Ageing. 2008;37(6):673–9.PubMedCrossRef Gallagher P, O’Mahony D. STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers’ criteria. Age Ageing. 2008;37(6):673–9.PubMedCrossRef
11.
go back to reference Gallagher P, Lang PO, Cherubini A, Topinkova E, Cruz-Jentoft A, Montero EB, et al. Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals. Eur J Clin Pharmacol. 2011;67(11):1175–88.PubMedCrossRef Gallagher P, Lang PO, Cherubini A, Topinkova E, Cruz-Jentoft A, Montero EB, et al. Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals. Eur J Clin Pharmacol. 2011;67(11):1175–88.PubMedCrossRef
12.
go back to reference Guaraldo L, Cano FG, Damasceno GS, Rozenfeld S. Inappropriate medication use among the elderly: a systematic review of administrative databases. BMC Geriatr. 2011;11(1):79.PubMedCrossRefPubMedCentral Guaraldo L, Cano FG, Damasceno GS, Rozenfeld S. Inappropriate medication use among the elderly: a systematic review of administrative databases. BMC Geriatr. 2011;11(1):79.PubMedCrossRefPubMedCentral
13.
go back to reference Hamilton H, Gallagher P, Ryan C, Byrne S, O’Mahony D. Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med. 2011;171(11):1013–9.PubMedCrossRef Hamilton H, Gallagher P, Ryan C, Byrne S, O’Mahony D. Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients. Arch Intern Med. 2011;171(11):1013–9.PubMedCrossRef
14.
go back to reference Ryan C, O’Mahony D, Kennedy J, Weedle P, Byrne S. Potentially inappropriate prescribing in an Irish elderly population in primary care. Br J Clin Pharmacol. 2009;68(6):936–47.PubMedCrossRefPubMedCentral Ryan C, O’Mahony D, Kennedy J, Weedle P, Byrne S. Potentially inappropriate prescribing in an Irish elderly population in primary care. Br J Clin Pharmacol. 2009;68(6):936–47.PubMedCrossRefPubMedCentral
16.
go back to reference Gallagher P, O’Mahony D. Inappropriate prescribing in older people. Rev Clin Gerontol. 2008;18:65–76.CrossRef Gallagher P, O’Mahony D. Inappropriate prescribing in older people. Rev Clin Gerontol. 2008;18:65–76.CrossRef
22.
go back to reference Campbell AJ, Robertson MC, Gardner MM, Norton RN, Buchner DM. Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial. J Am Geriatr Soc. 1999;47(7):850–3.PubMed Campbell AJ, Robertson MC, Gardner MM, Norton RN, Buchner DM. Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial. J Am Geriatr Soc. 1999;47(7):850–3.PubMed
23.
go back to reference Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev 2009;(2):CD007146. doi:10.1002/14651858.CD007146.pub2. Gillespie LD, Robertson MC, Gillespie WJ, Lamb SE, Gates S, Cumming RG, Rowe BH. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev 2009;(2):CD007146. doi:10.​1002/​14651858.​CD007146.​pub2.​
24.
go back to reference Haumschild MJ, Karfonta TL, Haumschild MS, Phillips SE. Clinical and economic outcomes of a fall-focused pharmaceutical intervention program. Am J Health Syst Pharm. 2003;60(10):1029–32.PubMed Haumschild MJ, Karfonta TL, Haumschild MS, Phillips SE. Clinical and economic outcomes of a fall-focused pharmaceutical intervention program. Am J Health Syst Pharm. 2003;60(10):1029–32.PubMed
25.
go back to reference Iyer S, Naganathan V, McLachlan AJ, Le Couteur DG. Medication withdrawal trials in people aged 65 years and older: a systematic review. Drugs Aging. 2008;25(12):1021–31.PubMedCrossRef Iyer S, Naganathan V, McLachlan AJ, Le Couteur DG. Medication withdrawal trials in people aged 65 years and older: a systematic review. Drugs Aging. 2008;25(12):1021–31.PubMedCrossRef
26.
go back to reference Lowrie R. The Glasgow pharmacy falls service. Pharm Manag. 2008;24(1):10–5. Lowrie R. The Glasgow pharmacy falls service. Pharm Manag. 2008;24(1):10–5.
27.
go back to reference van der Velde N, Stricker BH, Pols HA, van der Cammen TJ. Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol. 2007;63(2):232–7.PubMedCrossRefPubMedCentral van der Velde N, Stricker BH, Pols HA, van der Cammen TJ. Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol. 2007;63(2):232–7.PubMedCrossRefPubMedCentral
28.
go back to reference Zermansky AG, Alldred DP, Petty DR, Raynor DK, Freemantle N, Eastaugh J, et al. Clinical medication review by a pharmacist of elderly people living in care homes-randomised controlled trial. Age Ageing. 2006;35(6):586–91.PubMedCrossRef Zermansky AG, Alldred DP, Petty DR, Raynor DK, Freemantle N, Eastaugh J, et al. Clinical medication review by a pharmacist of elderly people living in care homes-randomised controlled trial. Age Ageing. 2006;35(6):586–91.PubMedCrossRef
29.
go back to reference O’Mahony D, Gallagher P, Ryan C, Byrne S, Hamilton H, Barry P, et al. STOPP & START criteria: a new approach to detecting potentially inappropriate prescribing in old age. Eur Geriatr Med. 2010;1(1):45–51.CrossRef O’Mahony D, Gallagher P, Ryan C, Byrne S, Hamilton H, Barry P, et al. STOPP & START criteria: a new approach to detecting potentially inappropriate prescribing in old age. Eur Geriatr Med. 2010;1(1):45–51.CrossRef
30.
go back to reference Wilson NM, Hilmer SN, March LM, Cameron ID, Lord SR, Seibel MJ, et al. Associations between drug burden index and falls in older people in residential aged care. J Am Geriatr Soc. 2011;59(5):875–80.PubMedCrossRef Wilson NM, Hilmer SN, March LM, Cameron ID, Lord SR, Seibel MJ, et al. Associations between drug burden index and falls in older people in residential aged care. J Am Geriatr Soc. 2011;59(5):875–80.PubMedCrossRef
31.
go back to reference Casteel C, Blalock SJ, Ferreri S, Roth MT, Demby KB. Implementation of a community pharmacy-based falls prevention program. Am J Geriatr Pharmacother. 2011;9(5):310–9.PubMedCrossRef Casteel C, Blalock SJ, Ferreri S, Roth MT, Demby KB. Implementation of a community pharmacy-based falls prevention program. Am J Geriatr Pharmacother. 2011;9(5):310–9.PubMedCrossRef
32.
go back to reference Patel S, Chahine-Chakhtoura C. Impact of a pharmacist-driven consult service for falls prevention. [Conference abstract] American Society of Health-System Pharmacy Midyear Clinical Meeting, Nevada, 2009. Patel S, Chahine-Chakhtoura C. Impact of a pharmacist-driven consult service for falls prevention. [Conference abstract] American Society of Health-System Pharmacy Midyear Clinical Meeting, Nevada, 2009.
Metadata
Title
Falls prevention focused medication review by a pharmacist in an acute hospital: implications for future practice
Authors
Claire Browne
Claire Kingston
Claire Keane
Publication date
01-10-2014
Publisher
Springer Netherlands
Published in
International Journal of Clinical Pharmacy / Issue 5/2014
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-014-9980-3

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