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International Journal of Clinical Pharmacy

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01-02-2011 | Case Report

Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia

Authors: T. Bauters, V. Mondelaers, H. Robays, H. De Wilde, Y. Benoit, B. De Moerloose

Published in: International Journal of Clinical Pharmacy | Issue 1/2011

Abstract

Case We report a case of simultaneous methemoglobinemia and hemolytic anemia, probably related to the use of rasburicase, in a child starting treatment for acute lymphoblastic leukemia (ALL). In addition, the patient developed symptoms of pancreatitis. All complications resolved after 3 days of supportive therapy. Conclusion Although usually well tolerated in pediatrics, physicians prescribing rasburicase should be aware of these possible life-threatening adverse reactions.

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Title: Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia
Authors: T. Bauters
V. Mondelaers
H. Robays
H. De Wilde
Y. Benoit
B. De Moerloose
Publication date: 01-02-2011
Publisher: Springer Netherlands
Published in: International Journal of Clinical Pharmacy / Issue 1/2011
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI: https://doi.org/10.1007/s11096-011-9484-3

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