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Published in: International Journal of Clinical Pharmacy 6/2010

01-12-2010 | Research Article

The Pharmaceutical care of patients with type 2 diabetes mellitus

Authors: Anna Paula de Sá Borges, Camilo Molino Guidoni, Lígia Domingues Ferreira, Osvaldo de Freitas, Leonardo Régis Leira Pereira

Published in: International Journal of Clinical Pharmacy | Issue 6/2010

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Abstract

Objective To evaluate the efficiency of pharmaceutical care on the control of clinical parameters, such as fasting glycaemia and glycosylated haemoglobin in patients with Type 2 Diabetes mellitus. Setting This study was conducted at the Training and Community Health Centre of the College of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil. Methods A prospective and experimental study was conducted with 71 participants divided in two groups: (i) pharmaceutical care group (n=40), and (ii) the control group (n=31). The distribution of patients within these groups was made casually, and the patients were monitored for 12 months. Main outcome measure: Values for fasting glycaemia and glycosylated haemoglobin were collected. Results Mean values of fasting glycaemia in the pharmaceutical care group were significantly reduced whilst a small reduction was detected in the control group at the same time. A significant reduction in the levels of glycosylated haemoglobin was detected in patients in the pharmaceutical care group, and an average increase was observed in the control group. Furthermore, the follow-up of the intervention group by a pharmacist contributed to the resolution of 62.7% of 142 drug therapy problems identified. Conclusion In Brazil, the information provided by a pharmacist to patients with Type 2 Diabetes mellitus increases compliance to treatment, solving or reducing the Drug Therapy Problem and, consequently, improving glycaemic control.
Literature
3.
go back to reference American Diabetes Association. Standards of medical care in diabetes. Diabetes Care. 2009;32(1):S13–61.CrossRef American Diabetes Association. Standards of medical care in diabetes. Diabetes Care. 2009;32(1):S13–61.CrossRef
4.
go back to reference Hepler CD, Strand LM. Opportunities and responsibilities in pharmaceutical care. Am J Hosp Pharm. 1990;47(3):533–43.PubMed Hepler CD, Strand LM. Opportunities and responsibilities in pharmaceutical care. Am J Hosp Pharm. 1990;47(3):533–43.PubMed
5.
go back to reference Hasegawa GR. Enhancing patients’ understanding of drug therapy. Am J Health Syst Pharm. 2004;61(23):2503.PubMed Hasegawa GR. Enhancing patients’ understanding of drug therapy. Am J Health Syst Pharm. 2004;61(23):2503.PubMed
6.
go back to reference Pereira LRL, Freitas O. The evolution of pharmaceutical care and the prospect for the Brazil. Braz J Pharm Sci. 2008;44(4):601–12. Pereira LRL, Freitas O. The evolution of pharmaceutical care and the prospect for the Brazil. Braz J Pharm Sci. 2008;44(4):601–12.
7.
go back to reference Castro MS, Chemello C, Pilger D, Junges F, Bohnen L, Zimmerman LM, et al. Pharmaceutical care in the management of patients with hypertension. Braz J Hypertens. 2006;13(3):198–202. Castro MS, Chemello C, Pilger D, Junges F, Bohnen L, Zimmerman LM, et al. Pharmaceutical care in the management of patients with hypertension. Braz J Hypertens. 2006;13(3):198–202.
8.
go back to reference Lyra-Júnior DP, Kheir N, Abriata JP, Rocha CE, Santos CB, Pelá IR. Impact of pharmaceutical care interventions in the identification and resolution of drug-related problems and on quality of life in a group of elderly outpatients in Ribeirão Preto (SP), Brazil. Ther Clin Risk Manag. 2007;3(6):989–98. Lyra-Júnior DP, Kheir N, Abriata JP, Rocha CE, Santos CB, Pelá IR. Impact of pharmaceutical care interventions in the identification and resolution of drug-related problems and on quality of life in a group of elderly outpatients in Ribeirão Preto (SP), Brazil. Ther Clin Risk Manag. 2007;3(6):989–98.
9.
go back to reference Strand LM, Cipolle RJ, Morley PC, Frakes MJ. The impact of pharmaceutical care practice on the practitioner and the patient in the ambulatory practice setting: twenty-five years of experience. Curr Pharm Des. 2004;10(31):3987–4001.CrossRefPubMed Strand LM, Cipolle RJ, Morley PC, Frakes MJ. The impact of pharmaceutical care practice on the practitioner and the patient in the ambulatory practice setting: twenty-five years of experience. Curr Pharm Des. 2004;10(31):3987–4001.CrossRefPubMed
10.
go back to reference Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of self-reported measure of medication adherence. Med Care. 1986;24(1):67–74.CrossRefPubMed Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of self-reported measure of medication adherence. Med Care. 1986;24(1):67–74.CrossRefPubMed
11.
go back to reference D’agostinho RB, Grundy S, Sullivan LM, Wilson P. Validation of the Framingham coronary heart disease prediction scores: result of a multiple ethnic groups investigation. JAMA. 2001;286(2):180–7.CrossRef D’agostinho RB, Grundy S, Sullivan LM, Wilson P. Validation of the Framingham coronary heart disease prediction scores: result of a multiple ethnic groups investigation. JAMA. 2001;286(2):180–7.CrossRef
12.
go back to reference Beckles GL, Engelgau MM, Narayan KM, Herman WH, Aubert RE, Williamson DF. Population-based assessment of the level of care among adults with diabetes in the US. Diabetes Care. 1998;21(9):1432–8.CrossRefPubMed Beckles GL, Engelgau MM, Narayan KM, Herman WH, Aubert RE, Williamson DF. Population-based assessment of the level of care among adults with diabetes in the US. Diabetes Care. 1998;21(9):1432–8.CrossRefPubMed
13.
go back to reference Harris MI. Medical care for patients with diabetes. epidemiologic aspects. Ann Intern Med. 1996;124(1):117–22.PubMed Harris MI. Medical care for patients with diabetes. epidemiologic aspects. Ann Intern Med. 1996;124(1):117–22.PubMed
14.
go back to reference Campbell RK. Role of the pharmacist in diabetes management. Am J Health Syst Pharm. 2002;59(9):S18–21.PubMed Campbell RK. Role of the pharmacist in diabetes management. Am J Health Syst Pharm. 2002;59(9):S18–21.PubMed
15.
go back to reference Clifford RM, Davis WA, Batty KT, Davis TM. Effect of a pharmaceutical care program on vascular risk factors in type 2 diabetes: the fremantle diabetes study. Diabetes Care. 2005;28(4):771–6.CrossRefPubMed Clifford RM, Davis WA, Batty KT, Davis TM. Effect of a pharmaceutical care program on vascular risk factors in type 2 diabetes: the fremantle diabetes study. Diabetes Care. 2005;28(4):771–6.CrossRefPubMed
16.
go back to reference Coast-senior EA, Kroner BA, Kelley CL, Trilli LE. Management of patients with type 2 diabetes by pharmacist in primary care clinics. Ann Pharmacother. 1998;32(6):636–41.CrossRefPubMed Coast-senior EA, Kroner BA, Kelley CL, Trilli LE. Management of patients with type 2 diabetes by pharmacist in primary care clinics. Ann Pharmacother. 1998;32(6):636–41.CrossRefPubMed
17.
go back to reference Davidson MB, Karlan VJ, Hair TL. Effect of a pharmacist-managed diabetes care program in a free medical clinic. Am J Med Qual. 2000;15(4):137–42.CrossRefPubMed Davidson MB, Karlan VJ, Hair TL. Effect of a pharmacist-managed diabetes care program in a free medical clinic. Am J Med Qual. 2000;15(4):137–42.CrossRefPubMed
18.
go back to reference Maccord AD. Clinical impact of a pharmacist-management diabetes mellitus drug therapy management service. Pharmacotherapy. 2006;26(2):248–53.CrossRef Maccord AD. Clinical impact of a pharmacist-management diabetes mellitus drug therapy management service. Pharmacotherapy. 2006;26(2):248–53.CrossRef
19.
go back to reference Anaya JP, Rivera JO, Lawson K, Garcia J, Luna JJ, Ortiz M. Evaluation of pharmacist-managed diabetes mellitus under a collaborative drug therapy agreement. Am J Health Syst Pharm. 2008;65(19):1841–5.CrossRefPubMed Anaya JP, Rivera JO, Lawson K, Garcia J, Luna JJ, Ortiz M. Evaluation of pharmacist-managed diabetes mellitus under a collaborative drug therapy agreement. Am J Health Syst Pharm. 2008;65(19):1841–5.CrossRefPubMed
20.
go back to reference Rothman R, Malone R, Bryant B, Horlen C, Pignone M. Pharmacist-led, primary care-based disease management improves hemoglobin HbA1c in high-risk patients with diabetes. Am J Med Qual. 2003;18(2):51–8.CrossRefPubMed Rothman R, Malone R, Bryant B, Horlen C, Pignone M. Pharmacist-led, primary care-based disease management improves hemoglobin HbA1c in high-risk patients with diabetes. Am J Med Qual. 2003;18(2):51–8.CrossRefPubMed
21.
go back to reference Irons BK, Lenz RJ, Anderson SL, Wharton B, Habeger B, Anderson G. A retrospective cohort analysis of the clinical effectiveness of a physician-pharmacist collaborative drug therapy management diabetes clinic. Pharmacotherapy. 2002;22(10):1294–300.CrossRefPubMed Irons BK, Lenz RJ, Anderson SL, Wharton B, Habeger B, Anderson G. A retrospective cohort analysis of the clinical effectiveness of a physician-pharmacist collaborative drug therapy management diabetes clinic. Pharmacotherapy. 2002;22(10):1294–300.CrossRefPubMed
22.
go back to reference Odegard PS, Goo A, Hummel J, Williamas KL, Gray SL. Caring for poorly controlled diabetes mellitus: a randomized pharmacist intervention. Ann Pharmacother. 2005;39(3):433–40.CrossRefPubMed Odegard PS, Goo A, Hummel J, Williamas KL, Gray SL. Caring for poorly controlled diabetes mellitus: a randomized pharmacist intervention. Ann Pharmacother. 2005;39(3):433–40.CrossRefPubMed
23.
go back to reference United Kingston Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes (UKPDS 38). BMJ. 1998;317(7160):703–13. United Kingston Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes (UKPDS 38). BMJ. 1998;317(7160):703–13.
24.
go back to reference Chiu YW, Chang JM, Lin LI, Chang PY, Lo WC, Wu LC, et al. Adherence to a diabetic care plan provides better glycemic control in ambulatory patients with type 2 diabetes. Kaohsiung J Med Sci. 2009;25(4):184–92.CrossRefPubMed Chiu YW, Chang JM, Lin LI, Chang PY, Lo WC, Wu LC, et al. Adherence to a diabetic care plan provides better glycemic control in ambulatory patients with type 2 diabetes. Kaohsiung J Med Sci. 2009;25(4):184–92.CrossRefPubMed
25.
go back to reference Carvalho CV, Duarte DB, Merchán-Hamann E, Bicudo E, Laguardia J. Predictors of compliance with highly active antiretroviral therapy in Brasilia, Distrito Federal, Brazil, 1999–2000. Cad Saude Publica. 2003;19(2):593–604.CrossRefPubMed Carvalho CV, Duarte DB, Merchán-Hamann E, Bicudo E, Laguardia J. Predictors of compliance with highly active antiretroviral therapy in Brasilia, Distrito Federal, Brazil, 1999–2000. Cad Saude Publica. 2003;19(2):593–604.CrossRefPubMed
26.
go back to reference Odegard OS, Gray SL. Barriers to medication adherence in poorly controlled diabetes mellitus. Diabetes Educ. 2008;34(4):692–7.CrossRefPubMed Odegard OS, Gray SL. Barriers to medication adherence in poorly controlled diabetes mellitus. Diabetes Educ. 2008;34(4):692–7.CrossRefPubMed
27.
go back to reference Odegard PS, Capoccia K. Medication taking and diabetes: a systematic review of the literature. Diabetes Educ. 2007;33(6):1014–29.CrossRefPubMed Odegard PS, Capoccia K. Medication taking and diabetes: a systematic review of the literature. Diabetes Educ. 2007;33(6):1014–29.CrossRefPubMed
29.
go back to reference Rao D, Gilbert A, Strand LM, Cipolle RJ. Drug therapy problems found in ambulatory patient populations in Minnesota and South Australia. Pharm World Sci. 2007;29(6):647–54.CrossRefPubMed Rao D, Gilbert A, Strand LM, Cipolle RJ. Drug therapy problems found in ambulatory patient populations in Minnesota and South Australia. Pharm World Sci. 2007;29(6):647–54.CrossRefPubMed
30.
go back to reference Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and non-diabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339(4):229–34.CrossRefPubMed Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and non-diabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339(4):229–34.CrossRefPubMed
31.
go back to reference Oliveira DS, Tannus LR, Matheus AS, Corrêa FH, Cobas R, Cunha EF, et al. Evaluation of cardiovascular risk according to Framingham criteria in patients with type 2 diabetes. Arq Bras Endocrinol Metabol. 2007;51(2):268–74.PubMed Oliveira DS, Tannus LR, Matheus AS, Corrêa FH, Cobas R, Cunha EF, et al. Evaluation of cardiovascular risk according to Framingham criteria in patients with type 2 diabetes. Arq Bras Endocrinol Metabol. 2007;51(2):268–74.PubMed
Metadata
Title
The Pharmaceutical care of patients with type 2 diabetes mellitus
Authors
Anna Paula de Sá Borges
Camilo Molino Guidoni
Lígia Domingues Ferreira
Osvaldo de Freitas
Leonardo Régis Leira Pereira
Publication date
01-12-2010
Publisher
Springer Netherlands
Published in
International Journal of Clinical Pharmacy / Issue 6/2010
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-010-9428-3

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