Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Neuropsychology Review
Published in: Neuropsychology Review 2/2018

01-06-2018 | Review

The Study of Language in the Amyotrophic Lateral Sclerosis - Frontotemporal Spectrum Disorder: a Systematic Review of Findings and New Perspectives

Published in: Neuropsychology Review | Issue 2/2018

Login to get access

Abstract

Amyotrophic Lateral Sclerosis is a neurodegenerative disorder characterized primarily by motor network disruption. Extra-motor manifestations including executive functions, social cognition, and behavioral changes are now well recognized as important features of ALS, and are associated with frontotemporal and frontostriatal network disruption. However, the presence and characterization of language changes has received less attention. This systematic review characterizes the profile of reported language dysfunction in ALS. PRISMA guidelines were implemented to carry out and report the review. Current evidence suggests that areas of neuroanatomical disruption in ALS spread to language centers such as posterior, inferior frontal and superior temporal areas leading to deficits in word retrieval, syntactic and grammatical processing, and spelling. However, the majority of studies of language in ALS have been limited by the recruitment of small clinic-based prevalent samples and important questions remain regarding the incidence and progression of language impairment in ALS. Further studies from population-based incident cohorts will help to determine the range of language deficits in ALS, and how these relate to previously defined executive and behavioral sub-phenotypes.
Literature
Abe, K., Fujimura, H., Toyooka, K., Sakoda, S., Yorifuji, S., & Yanagihara, T. (1997). Cognitive function in amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 148(1), 95–100.CrossRefPubMed
Abrahams, S. (2013). Executive dysfunction in ALS is not the whole story. Journal of Neurology, Neurosurgery, and Psychiatry, 84(5), 474–475.CrossRefPubMed
Abrahams, S., Leigh, P. N., Kew, J. J., Goldstein, L. H., Lloyd, C. M., & Brooks, D. J. (1995). A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 129(Suppl), 44–46.CrossRefPubMed
Abrahams, S., Goldstein, L. H., Kew, J. J., Brooks, D. J., Lloyd, C. M., Frith, C. D., & Leigh, P. N. (1996). Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study. Brain, 119(Pt 6), 2105–2120.CrossRefPubMed
Abrahams, S., Goldstein, L. H., Al-Chalabi, A., Pickering, A., Morris, R. G., Passingham, R. E., et al. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry, 62(5), 464–472.CrossRefPubMedPubMedCentral
Abrahams, S., Leigh, P. N., Harvey, A., Vythelingum, G. N., Grise, D., & Goldstein, L. H. (2000). Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38(6), 734–747.CrossRefPubMed
Abrahams, S., Goldstein, L. H., Simmons, A., Brammer, M. J., Williams, S. C., Giampietro, V. P., et al. (2003). Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses. Human Brain Mapping, 20(1), 29–40.CrossRefPubMed
Abrahams, S., Goldstein, L. H., Simmons, A., Brammer, M., Williams, S. C., Giampietro, V., & Leigh, P. N. (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127(Pt 7), 1507–1517.CrossRefPubMed
Abrahams, S., Goldstein, L. H., Suckling, J., Ng, V., Simmons, A., Chitnis, X., et al. (2005a). Frontotemporal white matter changes in amyotrophic lateral sclerosis. Journal of Neurology, 252(3), 321–331.CrossRefPubMed
Abrahams, S., Leigh, P. N., & Goldstein, L. H. (2005b). Cognitive change in ALS: a prospective study. Neurology, 64(7), 1222–1226.CrossRefPubMed
Ash, S., Menaged, A., Olm, C., McMillan, C. T., Boller, A., Irwin, D. J., McCluskey, L., Elman, L., & Grossman, M. (2014). Narrative discourse deficits in amyotrophic lateral sclerosis. Neurology, 83(6), 520–528.CrossRefPubMedPubMedCentral
Baddeley, A., Emslie, H., & Nimmo-Smith, I. (1993). The spot-the-word test: a robust estimate of verbal intelligence based on lexical decision. The British Journal of Clinical Psychology, 32(Pt 1), 55–65.CrossRefPubMed
Bak, T. H., & Chandran, S. (2012). What wires together dies together: verbs, actions and neurodegeneration in motor neuron disease. Cortex, 48(7), 936–944.CrossRefPubMed
Bak, T. H., & Hodges, J. R. (2003). Kissing and dancing—A test to distinguish the lexical and conceptual contributions to noun/verb and action/object dissociation. Preliminary results in patients with frontotemporal dementia. Journal of Neurolinguistics, 16(2), 169–181.CrossRef
Bak, T. H., & Hodges, J. R. (2004). The effects of motor neurone disease on language: further evidence. Brain and Language, 89(2), 354–361.CrossRefPubMed
Bak, T. H., O'Donovan, D. G., Xuereb, J. H., Boniface, S., & Hodges, J. R. (2001). Selective impairment of verb processing associated with pathological changes in Brodmann areas 44 and 45 in the motor neurone disease-dementia-aphasia syndrome. Brain, 124(Pt 1), 103–120.CrossRefPubMed
Baxter, D. M., & Warrington, E. K. (1994). Measuring dysgraphia: a graded-difficulty spelling test. Behavioural Neurology, 7(3), 107–116.CrossRefPubMed
Beeldman, E., Raaphorst, J., Klein Twennaar, M., de Visser, M., Schmand, B. A., & de Haan, R. J. (2016). The cognitive profile of ALS: a systematic review and meta-analysis update. Journal of Neurology, Neurosurgery, and Psychiatry, 87(6), 611–619.CrossRefPubMed
Benton, A. (1967). FAS test. Victoria: University of Victoria.
Bishop, D. (1982). TROG: Test for reception oj grammar. Printed for the Medical Research Council by Thomas Leach, Abingdon. Oxon. England.
Burke, T., Pinto-Grau, M., Lonergan, K., Bede, P., O'Sullivan, M., Heverin, M., Vajda, A., McLaughlin, R. L., Pender, N., & Hardiman, O. (2017). A cross-sectional population-based investigation into behavioral change in amyotrophic lateral sclerosis: subphenotypes, staging, cognitive predictors, and survival. Annals of Clinical Translational Neurology, 4(5), 305–317.CrossRefPubMedPubMedCentral
Burrell, J. R., Halliday, G. M., Kril, J. J., Ittner, L. M., Gotz, J., Kiernan, M. C., & Hodges, J. R. (2016). The frontotemporal dementia-motor neuron disease continuum. Lancet, 388(10047), 919–931.CrossRefPubMed
Caltagirone, C., Gainotti, G., Masullo, C., & Miceli, G. (1979). Validity of some neuropsychological tests in the assessment of mental deterioration. Acta Psychiatrica Scandinavica, 60(1), 50–56.CrossRefPubMed
Cardona, J. F., Gershanik, O., Gelormini-Lezama, C., Houck, A. L., Cardona, S., Kargieman, L., et al. (2013). Action-verb processing in Parkinson’s disease: new pathways for motor–language coupling. Brain Structure and Function, 218(6), 1355–1373.CrossRefPubMed
Cobble, M. (1998). Language impairment in motor neurone disease. Journal of the Neurological Sciences, 160(Suppl 1), S47–S52.CrossRefPubMed
Consonni, M., Iannaccone, S., Cerami, C., Frasson, P., Lacerenza, M., Lunetta, C., Corbo, M., & Cappa, S. F. (2013). The cognitive and behavioural profile of amyotrophic lateral sclerosis: application of the consensus criteria. Behavioural Neurology, 27(2), 143–153.CrossRefPubMedPubMedCentral
Consonni, M., Catricalà, E., Dalla Bella, E., Gessa, V. C., Lauria, G., & Cappa, S. F. (2016). Beyond the consensus criteria: multiple cognitive profiles in amyotrophic lateral sclerosis? Cortex, 81, 162–167.CrossRefPubMed
Cousins, K. A., Ash, S., & Grossman, M. (2017). Production of verbs related to body movement in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). Cortex, 100, 127–139.
De Renzi, E., & Vignolo, L. A. (1962). The token test: a sensitive test to detect receptive disturbances in aphasics. Brain, 85(4), 665–678.CrossRef
Démonet, J.-F., Thierry, G., & Cardebat, D. (2005). Renewal of the neurophysiology of language: functional neuroimaging. Physiological Reviews, 85(1), 49–95.CrossRefPubMed
Donaghy, C., Pinnock, R., Abrahams, S., Cardwell, C., Hardiman, O., Patterson, V., McGivern, R. C., & Gibson, J. M. (2009). Ocular fixation instabilities in motor neurone disease. A marker of frontal lobe dysfunction? Journal of Neurology, 256(3), 420–426.CrossRefPubMed
Duffy, J. R., Peach, R. K., & Strand, E. A. (2007). Progressive apraxia of speech as a sign of motor neuron disease. American Journal of Speech-Language Pathology, 16(3), 198–208.CrossRefPubMed
Dunn, L. M., & Dunn, D. M. (1997). PPVT-III: Peabody picture vocabulary test: American guidance service circle pines, MN.
Dunn, L. M., Dunn, D. M., Whetton, C., & Burley, J. (1997). The British picture vocabulary scale (2nd ed.). Windsor: NFER-Nelson.
Elamin, M., Bede, P., Byrne, S., Jordan, N., Gallagher, L., Wynne, B., O'Brien, C., Phukan, J., Lynch, C., Pender, N., & Hardiman, O. (2013). Cognitive changes predict functional decline in ALS: a population-based longitudinal study. Neurology, 80(17), 1590–1597.CrossRefPubMed
Ferguson, J. H., & Boller, F. (1977). A different form of agraphia: syntactic writing errors in patients with motor speech and movement disorders. Brain and Language, 4(3), 382–389.CrossRefPubMed
Frank, B., Haas, J., Heinze, H. J., Stark, E., & Munte, T. F. (1997). Relation of neuropsychological and magnetic resonance findings in amyotrophic lateral sclerosis: evidence for subgroups. Clinical Neurology and Neurosurgery, 99(2), 79–86.CrossRefPubMed
Gallassi, R., Montagna, P., Ciardulli, C., Lorusso, S., Mussuto, V., & Stracciari, A. (1985). Cognitive impairment in motor neuron disease. Acta Neurologica Scandinavica, 71(6), 480–484.CrossRefPubMed
Goldstein, L. H., & Abrahams, S. (2013). Changes in cognition and behaviour in amyotrophic lateral sclerosis: nature of impairment and implications for assessment. Lancet Neurology, 12(4), 368–380.CrossRefPubMed
Goodglass, H., & Kaplan, E. (1983). Boston diagnostic aphasia examination booklet: Lea & Febiger.
Gordon, P. H., Goetz, R. R., Rabkin, J. G., Dalton, K., McElhiney, M., Hays, A. P., et al. (2010). A prospective cohort study of neuropsychological test performance in ALS. Amyotrophic Lateral Sclerosis, 11(3), 312–320.CrossRefPubMed
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. F., Ogar, J. M., Rohrer, J. D., Black, S., Boeve, B. F., Manes, F., Dronkers, N. F., Vandenberghe, R., Rascovsky, K., Patterson, K., Miller, B. L., Knopman, D. S., Hodges, J. R., Mesulam, M. M., & Grossman, M. (2011). Classification of primary progressive aphasia and its variants. Neurology, 76(11), 1006–1014.CrossRefPubMedPubMedCentral
Grossman, M., Anderson, C., Khan, A., Avants, B., Elman, L., & McCluskey, L. (2008). Impaired action knowledge in amyotrophic lateral sclerosis. Neurology, 71(18), 1396–1401.CrossRefPubMedPubMedCentral
Hanagasi, H. A., Gurvit, I. H., Ermutlu, N., Kaptanoglu, G., Karamursel, S., Idrisoglu, H. A., Emre, M., & Demiralp, T. (2002). Cognitive impairment in amyotrophic lateral sclerosis: evidence from neuropsychological investigation and event-related potentials. Brain Research. Cognitive Brain Research, 14(2), 234–244.CrossRefPubMed
Hartikainen, P., Helkala, E. L., Soininen, H., & Riekkinen Sr., P. (1993). Cognitive and memory deficits in untreated Parkinson's disease and amyotrophic lateral sclerosis patients: a comparative study. Journal of Neural Transmission. Parkinson's Disease and Dementia Section, 6(2), 127–137.CrossRefPubMed
Hauk, O., Johnsrude, I., & Pulvermuller, F. (2004). Somatotopic representation of action words in human motor and premotor cortex. Neuron, 41(2), 301–307.CrossRefPubMed
Higuchi, H., Moriguchi, Y., Murakami, H., Katsunuma, R., Mishima, K., & Uno, A. (2015). Neural basis of hierarchical visual form processing of Japanese kanji characters. Brain and Behavior, 5(12), e00413.
Hodges, J. R., Salmon, D. P., & Butters, N. (1991). The nature of the naming deficit in Alzheimer's and Huntington's disease. Brain, 114(Pt 4), 1547–1558.CrossRefPubMed
Howard, D., & Patterson, K. (1992). Pyramids and palm trees. Bury St. Edmonds: Thames Valley Test Company.
Ichikawa, H., Takahashi, N., Hieda, S., Ohno, H., & Kawamura, M. (2008). Agraphia in bulbar-onset amyotrophic lateral sclerosis: not merely a consequence of dementia or aphasia. Behavioural Neurology, 20(3), 91–99.CrossRefPubMed
Kamminga, J., Leslie, F. V., Hsieh, S., Caga, J., Mioshi, E., Hornberger, M., et al. (2016). Syntactic comprehension deficits across the FTD-ALS continuum. Neurobiology of Aging, 41, 11–18.CrossRefPubMed
Kaplan, E., Goodglass, H., & Weintraub, S. (1983). The Boston naming test (ed2 ed.). Philadelphia: Lea & Febiger.
Kay, J., Lesser, R., & Coltheart, M. (1996). Psycholinguistic assessments of language processing in aphasia (PALPA): an introduction. Aphasiology, 10(2), 159–180.CrossRef
Kertesz, A. (1982). Western aphasia battery test manual: Psychological Corp.
Kew, J. J., Goldstein, L. H., Leigh, P. N., Abrahams, S., Cosgrave, N., Passingham, R. E., et al. (1993). The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study. Brain, 116(Pt 6), 1399–1423.CrossRefPubMed
Kielar, A., Milman, L., Bonakdarpour, B., & Thompson, C. K. (2011). Neural correlates of covert and overt production of tense and agreement morphology: evidence from fMRI. Journal of Neurolinguistics, 24(2), 183–201.CrossRefPubMedPubMedCentral
Kilani, M., Micallef, J., Soubrouillard, C., Rey-Lardiller, D., Demattei, C., Dib, M., et al. (2004). A longitudinal study of the evolution of cognitive function and affective state in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders, 5(1), 46–54.CrossRefPubMed
Lattante, S., Ciura, S., Rouleau, G. A., & Kabashi, E. (2015). Defining the genetic connection linking amyotrophic lateral sclerosis (ALS) with frontotemporal dementia (FTD). Trends in Genetics, 31(5), 263–273.CrossRefPubMed
Lepow, L., Van Sweringen, J., Strutt, A. M., Jawaid, A., MacAdam, C., Harati, Y., et al. (2010). Frontal and temporal lobe involvement on verbal fluency measures in amyotrophic lateral sclerosis. Journal of Clinical and Experimental Neuropsychology, 32(9), 913–922.CrossRefPubMed
Leslie, F. V., Hsieh, S., Caga, J., Savage, S. A., Mioshi, E., Hornberger, M., et al. (2015). Semantic deficits in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener, 16(1–2), 46–53.CrossRefPubMed
Lezak, M. D. (2004). Neuropsychological assessment. USA: Oxford University Press.
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Medicine, 6(7), e1000100.CrossRefPubMedPubMedCentral
Ling, S. C., Polymenidou, M., & Cleveland, D. W. (2013). Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron, 79(3), 416–438.CrossRefPubMedPubMedCentral
Lomen-Hoerth, C., Murphy, J., Langmore, S., Kramer, J. H., Olney, R. K., & Miller, B. (2003). Are amyotrophic lateral sclerosis patients cognitively normal? Neurology, 60(7), 1094–1097.CrossRefPubMed
Ludolph, A. C., Langen, K. J., Regard, M., Herzog, H., Kemper, B., Kuwert, T., Böttger, I. G., & Feinendegen, L. (1992). Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study. Acta Neurologica Scandinavica, 85(2), 81–89.CrossRefPubMed
Mantovan, M. C., Baggio, L., Dalla Barba, G., Smith, P., Pegoraro, E., Soraru, G., et al. (2003). Memory deficits and retrieval processes in ALS. European Journal of Neurology, 10(3), 221–227.CrossRefPubMed
Massman, P. J., Sims, J., Cooke, N., Haverkamp, L. J., Appel, V., & Appel, S. H. (1996). Prevalence and correlates of neuropsychological deficits in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry, 61(5), 450–455.CrossRefPubMedPubMedCentral
McKenna, P. (1998). Category-specific names test: Psychology Press.
McKenna, P., & Warrington, E. K. (1983). Graded naming test: Manual: NFER-Nelson.
Miceli, G., Laudanna, A., Burani, C., & Capasso, R. (1994). Batteria per l'Analisi del deficit Afasico. BADA [BADA a battery for the assessment of aphasic disorders]. Roma: CEPSAG.
Mioshi, E., Dawson, K., Mitchell, J., Arnold, R., & Hodges, J. R. (2006). The Addenbrooke's cognitive examination revised (ACE-R): a brief cognitive test battery for dementia screening. International Journal of Geriatric Psychiatry, 21(11), 1078–1085.CrossRefPubMed
Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., et al. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic Reviews, 4(1), 1.CrossRefPubMedPubMedCentral
Montuschi, A., Iazzolino, B., Calvo, A., Moglia, C., Lopiano, L., Restagno, G., Brunetti, M., Ossola, I., Lo Presti, A., Cammarosano, S., Canosa, A., & Chio, A. (2015). Cognitive correlates in amyotrophic lateral sclerosis: a population-based study in Italy. Journal of Neurology, Neurosurgery, and Psychiatry, 86(2), 168–173.CrossRefPubMed
Moretti, R., Torre, P., Antonello, R. M., Carraro, N., Cazzato, G., & Bava, A. (2002). Complex cognitive disruption in motor neuron disease. Dementia and Geriatric Cognitive Disorders, 14(3), 141–150.CrossRefPubMed
Nelson, H. E., & Willison, J. (1991). National Adult Reading Test (NART): Nfer-Nelson Windsor.
Ochsner, K., & Kosslyn, S. M. (2017). The Oxford Handbook of Cognitive Neuroscience (Vol. 1, 2nd ed.). New York: Oxford University Press Inc.
Oh, S. I., Park, A., Kim, H. J., Oh, K. W., Choi, H., Kwon, M. J., et al. (2014). Spectrum of cognitive impairment in Korean ALS patients without known genetic mutations. PLoS One, 9(2), e87163.CrossRefPubMedPubMedCentral
Papeo, L., Cecchetto, C., Mazzon, G., Granello, G., Cattaruzza, T., Verriello, L., et al. (2015). The processing of actions and action-words in amyotrophic lateral sclerosis patients. Cortex, 64, 136–147.CrossRefPubMed
Paradis, M., & Canzanella, M. (1990). Test per l'afasia in un bilingue. Hillsdale: Versione italiana.
Pettit, L., Bastin, M., & Abrahams, S. (2013). Cognitive impairments in als relate to white matter integrity in specific regions of interest. Journal of Neurology, Neurosurgery & Psychiatry, 84(9), e1-e1.CrossRef
Phukan, J., Pender, N. P., & Hardiman, O. (2007). Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurology, 6(11), 994–1003.CrossRefPubMed
Phukan, J., Elamin, M., Bede, P., Jordan, N., Gallagher, L., Byrne, S., Lynch, C., Pender, N., & Hardiman, O. (2012). The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study. Journal of Neurology, Neurosurgery, and Psychiatry, 83(1), 102–108.CrossRefPubMed
Pulvermuller, F., Lutzenberger, W., & Preissl, H. (1999). Nouns and verbs in the intact brain: evidence from event-related potentials and high-frequency cortical responses. Cerebral Cortex, 9(5), 497–506.CrossRefPubMed
Pulvermuller, F., Hauk, O., Nikulin, V. V., & Ilmoniemi, R. J. (2005). Functional links between motor and language systems. The European Journal of Neuroscience, 21(3), 793–797.CrossRefPubMed
Raaphorst, J., de Visser, M., Linssen, W. H., de Haan, R. J., & Schmand, B. (2010). The cognitive profile of amyotrophic lateral sclerosis: a meta-analysis. Amyotrophic Lateral Sclerosis, 11(1–2), 27–37.CrossRefPubMed
Rakowicz, W. P., & Hodges, J. R. (1998). Dementia and aphasia in motor neuron disease: an underrecognised association? Journal of Neurology, Neurosurgery, and Psychiatry, 65(6), 881–889.CrossRefPubMedPubMedCentral
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., Hillis, A. E., Josephs, K. A., Boeve, B. F., Kertesz, A., Seeley, W. W., Rankin, K. P., Johnson, J. K., Gorno-Tempini, M. L., Rosen, H., Prioleau-Latham, C. E., Lee, A., Kipps, C. M., Lillo, P., Piguet, O., Rohrer, J. D., Rossor, M. N., Warren, J. D., Fox, N. C., Galasko, D., Salmon, D. P., Black, S. E., Mesulam, M., Weintraub, S., Dickerson, B. C., Diehl-Schmid, J., Pasquier, F., Deramecourt, V., Lebert, F., Pijnenburg, Y., Chow, T. W., Manes, F., Grafman, J., Cappa, S. F., Freedman, M., Grossman, M., & Miller, B. L. (2011). Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain, 134(Pt 9), 2456–2477.CrossRefPubMedPubMedCentral
Ringholz, G. M., Appel, S. H., Bradshaw, M., Cooke, N. A., Mosnik, D. M., & Schulz, P. E. (2005). Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology, 65(4), 586–590.CrossRefPubMed
Rippon, G. A., Scarmeas, N., Gordon, P. H., Murphy, P. L., Albert, S. M., Mitsumoto, H., Marder, K., Rowland, L. P., & Stern, Y. (2006). An observational study of cognitive impairment in amyotrophic lateral sclerosis. Archives of Neurology, 63(3), 345–352.CrossRefPubMed
Roberts-South, A., Findlater, K., Strong, M. J., & Orange, J. B. (2012). Longitudinal changes in discourse production in amyotrophic lateral sclerosis. Seminars in Speech and Language, 33(1), 79–94.CrossRefPubMed
Robinson, K. M., Lacey, S. C., Grugan, P., Glosser, G., Grossman, M., & McCluskey, L. F. (2006). Cognitive functioning in sporadic amyotrophic lateral sclerosis: a six month longitudinal study. Journal of Neurology, Neurosurgery, and Psychiatry, 77(5), 668–670.CrossRefPubMedPubMedCentral
Sarro, L., Agosta, F., Canu, E., Riva, N., Prelle, A., Copetti, M., et al. (2011). Cognitive functions and white matter tract damage in amyotrophic lateral sclerosis: a diffusion tensor tractography study. AJNR. American Journal of Neuroradiology, 32(10), 1866–1872.CrossRefPubMed
Satoh, M., Takeda, K., & Kuzuhara, S. (2009). Agraphia in intellectually normal Japanese patients with ALS: omission of kana letters. Journal of Neurology, 256(9), 1455–1460.CrossRefPubMed
Savage, S., Hsieh, S., Leslie, F., Foxe, D., Piguet, O., & Hodges, J. R. (2013). Distinguishing subtypes in primary progressive aphasia: application of the Sydney language battery. Dementia and Geriatric Cognitive Disorders, 35(3–4), 208–218.CrossRefPubMed
Saxon, J. A., Harris, J. M., Thompson, J. C., Jones, M., Richardson, A. M., Langheinrich, T., et al. (2017a). Semantic dementia, progressive non-fluent aphasia and their association with amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry, 88(8), 711–712.
Saxon, J. A., Thompson, J. C., Jones, M., Harris, J. M., Richardson, A. M., Langheinrich, T., et al. (2017b). Examining the language and behavioural profile in FTD and ALS-FTD. Journal of Neurology, Neurosurgery, and Psychiatry, 88(8), 675–680.
Schreiber, H., Gaigalat, T., Wiedemuth-Catrinescu, U., Graf, M., Uttner, I., Muche, R., & Ludolph, A. C. (2005). Cognitive function in bulbar- and spinal-onset amyotrophic lateral sclerosis. A longitudinal study in 52 patients. Journal of Neurology, 252(7), 772–781.CrossRefPubMed
Strauss, E., Sherman, E. M., & Spreen, O. (2006). A compendium of neuropsychological tests: Administration, norms, and commentary: American Chemical Society.
Strong, M. J., Grace, G. M., Orange, J. B., & Leeper, H. A. (1996). Cognition, language, and speech in amyotrophic lateral sclerosis: a review. Journal of Clinical and Experimental Neuropsychology, 18(2), 291–303.CrossRefPubMed
Strong, M. J., Grace, G. M., Orange, J. B., Leeper, H. A., Menon, R. S., & Aere, C. (1999). A prospective study of cognitive impairment in ALS. Neurology, 53(8), 1665–1670.CrossRefPubMed
Strong, M. J., Abrahams, S., Goldstein, L. H., Woolley, S., McLaughlin, P., Snowden, J., et al. (2017). Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): revised diagnostic criteria. Amyotroph Lateral Scler Frontotemporal Degener, 18(3-4), 1–22.CrossRef
Talbot, P. R., Goulding, P. J., Lloyd, J. J., Snowden, J. S., Neary, D., & Testa, H. J. (1995). Inter-relation between "classic" motor neuron disease and frontotemporal dementia: neuropsychological and single photon emission computed tomography study. Journal of Neurology, Neurosurgery, and Psychiatry, 58(5), 541–547.CrossRefPubMedPubMedCentral
Taylor, L. J., Brown, R. G., Tsermentseli, S., Al-Chalabi, A., Shaw, C. E., Ellis, C. M., et al. (2013). Is language impairment more common than executive dysfunction in amyotrophic lateral sclerosis? Journal of Neurology, Neurosurgery, and Psychiatry, 84(5), 494–498.CrossRefPubMed
Thurstone, L. L. (1938). Primary mental abilities.
Tsermentseli, S., Leigh, P. N., & Goldstein, L. H. (2012). The anatomy of cognitive impairment in amyotrophic lateral sclerosis: more than frontal lobe dysfunction. Cortex, 48(2), 166–182.CrossRefPubMed
Tsermentseli, S., Leigh, P. N., Taylor, L. J., Radunovic, A., Catani, M., & Goldstein, L. H. (2015). Syntactic processing as a marker for cognitive impairment in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener, 17(1–2), 69–76.PubMedPubMedCentral
Tsuji-Akimoto, S., Hamada, S., Yabe, I., Tamura, I., Otsuki, M., Kobashi, S., & Sasaki, H. (2010). Writing errors as a result of frontal dysfunction in Japanese patients with amyotrophic lateral sclerosis. Journal of Neurology, 257(12), 2071–2077.CrossRefPubMed
Van Der Hulst, E. J., Abrahams, S., & Bak, T. (2010). The nature of language deficits in ALS: semantic impairment in action sequencing. Paper presented at the 21st International Symposium on ALS/MND, Berlin.
van Es, M. A., Hardiman, O., Chio, A., Al-Chalabi, A., Pasterkamp, R. J., Veldink, J. H., & van den Berg, L. H. (2017). Amyotrophic lateral sclerosis. The Lancet, 390(10107), 4–10.
Vigliocco, G., Vinson, D. P., Druks, J., Barber, H., & Cappa, S. F. (2011). Nouns and verbs in the brain: a review of behavioural, electrophysiological, neuropsychological and imaging studies. Neuroscience & Biobehavioral Reviews, 35(3), 407–426.CrossRef
Wicks, P., Turner, M. R., Abrahams, S., Hammers, A., Brooks, D. J., Leigh, P. N., & Goldstein, L. H. (2008). Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study. Amyotrophic Lateral Sclerosis, 9(1), 43–49.CrossRefPubMed
Woolley, S. C., Zhang, Y., Schuff, N., Weiner, M. W., & Katz, J. S. (2011). Neuroanatomical correlates of apathy in ALS using 4 tesla diffusion tensor MRI. Amyotrophic Lateral Sclerosis, 12(1), 52–58.CrossRefPubMed
Yabe, I., Tsuji-Akimoto, S., Shiga, T., Hamada, S., Hirata, K., Otsuki, M., et al. (2012). Writing errors in ALS related to loss of neuronal integrity in the anterior cingulate gyrus. Journal of the Neurological Sciences, 315(1–2), 55–59.CrossRefPubMed
York, C., Olm, C., Boller, A., McCluskey, L., Elman, L., Haley, J., Seltzer, E., Chahine, L., Woo, J., Rascovsky, K., McMillan, C., & Grossman, M. (2014). Action verb comprehension in amyotrophic lateral sclerosis and Parkinson's disease. Journal of Neurology, 261(6), 1073–1079.CrossRefPubMedPubMedCentral
Yoshizawa, K., Yasuda, N., Fukuda, M., Yukimoto, Y., Ogino, M., Hata, W., et al. (2014). Syntactic comprehension in patients with amyotrophic lateral sclerosis. Behavioural Neurology, 2014, 230578–230578.CrossRefPubMedPubMedCentral
Metadata
Title
The Study of Language in the Amyotrophic Lateral Sclerosis - Frontotemporal Spectrum Disorder: a Systematic Review of Findings and New Perspectives
Publication date
01-06-2018
Published in
Neuropsychology Review / Issue 2/2018
Print ISSN: 1040-7308
Electronic ISSN: 1573-6660
DOI
https://doi.org/10.1007/s11065-018-9375-7

Other articles of this Issue 2/2018

Neuropsychology Review 2/2018 Go to the issue

Review

A Systematic Review of Cognition in Chiari I Malformation

Review

Meta-Analysis of the Effects of Computerized Cognitive Training on Executive Functions: a Cross-Disciplinary Taxonomy for Classifying Outcome Cognitive Factors

Review

Neurodevelopmental consequences of pediatric cancer and its treatment: applying an early adversity framework to understanding cognitive, behavioral, and emotional outcomes

Review

Executive Functions in Children and Adolescents with Turner Syndrome: A Systematic Review and Meta-Analysis

Review

Neurocognitive Functioning in Depressed Young People: A Systematic Review and Meta-Analysis