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01-11-2010 | Case Report

Radiation-induced cerebellar high-grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report

Authors: Tomoya Kamide, Mitsutoshi Nakada, Yutaka Hayashi, Tomohide Suzuki, Yasuhiko Hayashi, Naoyuki Uchiyama, Tamotsu Kijima, Jun-ichiro Hamada

Published in: Journal of Neuro-Oncology | Issue 2/2010

Abstract

Here, we report the case of a patient with cerebellar high-grade glioma that developed after the patient underwent treatment for medulloblastoma. A 34-year-old man visited our hospital with complaints of dizziness and truncal ataxia. Magnetic resonance image showed a cerebellar tumor with multiple cavernomas and two lesions that were suspected to be meningiomas. The cerebellar tumor was surgically removed. According to pathological examination, the tumor was a high-grade glioma that was positive for methylated O-6-methylguanine-DNA methyltransferase promoter. In the past, he had received radiotherapy at the age of 5, after which he was operated for desmoplastic medulloblastoma in his right cerebellar hemisphere. Seven years after the initial therapy, cavernoma-induced intracerebral hemorrhage of the right temporal lobe was noted. To our knowledge, this is the first case of radiation-induced double intracranial tumors accompanied by symptomatic cavernoma.

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Title: Radiation-induced cerebellar high-grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report
Authors: Tomoya Kamide
Mitsutoshi Nakada
Yutaka Hayashi
Tomohide Suzuki
Yasuhiko Hayashi
Naoyuki Uchiyama
Tamotsu Kijima
Jun-ichiro Hamada
Publication date: 01-11-2010
Publisher: Springer US
Published in: Journal of Neuro-Oncology / Issue 2/2010
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-010-0166-0

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Radiation-induced cerebellar high-grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report

Abstract

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