Published in:
01-07-2007 | Imagers in neuron-oncology clinical-patient studies
Malignant astroblastoma with rhabdoid morphology
Published in: Journal of Neuro-Oncology | Issue 3/2007
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A 33-year-old man with complains of headache for about 2 months developed right-sided weakness and blurred vision. MRI revealed 50 mm in the greatest dimension right frontal mass, adjacent to leptomeninges of the superior orbital roof (Fig. 1A–C). The tumor was well circumscribed, surrounded by vasogenic edema and contained foci of hypointensity consistent with hemosiderin. Central portion appeared necrotic and there was irregular contrast enhancement. Intra-operatively, the tumor was strawberry colored, fleshy and edematous. Gross total resection was achieved.
Fig. 1
Axial MRI of the brain demonstrating well-circumscribed right frontal tumor, predominantly bright on T1 (A) and T2 (C), surrounded by vasogenic edema (A & B), and showing mainly peripheral enhancement (C). Histologically, the bulk of the tumor shows a perivascular growth of plump epitheliod cells with variably developed hyalinization of vascular stalks (D). The tumor is positive for GFAP (E)
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