Skip to main content
Top
Published in: Journal of Occupational Rehabilitation 2/2015

01-06-2015

Predictors of Presenteeism and Activity Impairment Outside Work in Patients with Spondyloarthritis

Authors: Emma Haglund, Ingemar F. Petersson, Ann Bremander, Stefan Bergman

Published in: Journal of Occupational Rehabilitation | Issue 2/2015

Login to get access

Abstract

Purposes To assess predictors of presenteeism (reduced productivity at work) and activity impairment outside work in patients with spondyloarthritis (SpA). Methods Multivariate logistic regression analysis was used to study predictors of presenteeism and activity impairment in 1,253 patients with SpA based on a 2.5 year follow-up questionnaire. The Work Productivity and Activity Impairment (WPAI) questionnaire was used as main outcome. Age, gender, lifestyle factors, subgroups, disease duration, and different patient reported outcome measures (PROMs) were studied as possible predictors. The association between presenteeism and WPAI activity impairment outside work was assessed. Results Out of 1,253 patients, 757 reported being in work and of these 720 responded to the WPAI questionnaire. The mean (confidence interval, CI) reported presenteeism was 25 % (23–27 %) and mean activity impairment 33 % (31–35 %) (0–100 %, 0 = no reduction). Significant predictors of presenteeism and activity impairment at follow-up (controlled for gender, age, spondyloarthritis subgroups and presenteeism at baseline) were presenteeism at baseline, poor quality of life, worse disease activity, decreased physical function, lower self-efficacy pain and symptom, higher scores of anxiety, depression, smoking and low education level, and for activity impairment also female sex. There was a strong association between presenteeism and activity impairment outside work (OR 16.7; 95 % CI 11.6–24.3; p < 0.001). Conclusions Presenteeism and activity impairment were not only predicted by presenteeism at baseline, but also by several PROMs commonly used in clinical rheumatology practice. Impaired activity outside work could indicate problems also at work suggesting why both areas need to be addressed in the clinical situation.
Literature
1.
go back to reference Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 1991;34:1218–27.CrossRefPubMed Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 1991;34:1218–27.CrossRefPubMed
2.
go back to reference Haglund E, Bremander AB, Petersson IF, Strombeck B, Bergman S, Jacobsson LT, et al. Prevalence of spondyloarthritis and its subtypes in southern Sweden. Ann Rheum Dis. 2011;70:943–8.CrossRefPubMed Haglund E, Bremander AB, Petersson IF, Strombeck B, Bergman S, Jacobsson LT, et al. Prevalence of spondyloarthritis and its subtypes in southern Sweden. Ann Rheum Dis. 2011;70:943–8.CrossRefPubMed
3.
go back to reference Rudwaleit M. New approaches to diagnosis and classification of axial and peripheral spondyloarthritis. Curr Opin Rheumatol. 2010;22:375–80.CrossRefPubMed Rudwaleit M. New approaches to diagnosis and classification of axial and peripheral spondyloarthritis. Curr Opin Rheumatol. 2010;22:375–80.CrossRefPubMed
4.
go back to reference Saraux A, Guillemin F, Guggenbuhl P, Roux CH, Fardellone P, Le Bihan E, et al. Prevalence of spondyloarthropathies in France: 2001. Ann Rheum Dis. 2005;64:1431–5.CrossRefPubMedCentralPubMed Saraux A, Guillemin F, Guggenbuhl P, Roux CH, Fardellone P, Le Bihan E, et al. Prevalence of spondyloarthropathies in France: 2001. Ann Rheum Dis. 2005;64:1431–5.CrossRefPubMedCentralPubMed
5.
go back to reference Boonen A. A review of work-participation, cost-of-illness and cost-effectiveness studies in ankylosing spondylitis. Nat Clin Pract Rheumatol. 2006;2:546–53.CrossRefPubMed Boonen A. A review of work-participation, cost-of-illness and cost-effectiveness studies in ankylosing spondylitis. Nat Clin Pract Rheumatol. 2006;2:546–53.CrossRefPubMed
6.
go back to reference Dagfinrud H, Kjeken I, Mowinckel P, Hagen KB, Kvien TK. Impact of functional impairment in ankylosing spondylitis: impairment, activity limitation, and participation restrictions. J Rheumatol. 2005;32:516–23.PubMed Dagfinrud H, Kjeken I, Mowinckel P, Hagen KB, Kvien TK. Impact of functional impairment in ankylosing spondylitis: impairment, activity limitation, and participation restrictions. J Rheumatol. 2005;32:516–23.PubMed
7.
8.
go back to reference Strombeck B, Jacobsson LT, Bremander A, Englund M, Heide A, Turkiewicz A, et al. Patients with ankylosing spondylitis have increased sick leave—a registry-based case–control study over 7 years. Rheumatology (Oxford). 2009;48:289–92.CrossRef Strombeck B, Jacobsson LT, Bremander A, Englund M, Heide A, Turkiewicz A, et al. Patients with ankylosing spondylitis have increased sick leave—a registry-based case–control study over 7 years. Rheumatology (Oxford). 2009;48:289–92.CrossRef
9.
go back to reference van Echteld I, Cieza A, Boonen A, Stucki G, Zochling J, Braun J, et al. Identification of the most common problems by patients with ankylosing spondylitis using the international classification of functioning, disability and health. J Rheumatol. 2006;33:2475–83.PubMed van Echteld I, Cieza A, Boonen A, Stucki G, Zochling J, Braun J, et al. Identification of the most common problems by patients with ankylosing spondylitis using the international classification of functioning, disability and health. J Rheumatol. 2006;33:2475–83.PubMed
10.
go back to reference Boonen A, Brinkhuizen T, Landewe R, van der Heijde D, Severens JL. Impact of ankylosing spondylitis on sick leave, presenteeism and unpaid productivity, and estimation of the societal cost. Ann Rheum Dis. 2010;69:1123–8.CrossRefPubMed Boonen A, Brinkhuizen T, Landewe R, van der Heijde D, Severens JL. Impact of ankylosing spondylitis on sick leave, presenteeism and unpaid productivity, and estimation of the societal cost. Ann Rheum Dis. 2010;69:1123–8.CrossRefPubMed
11.
go back to reference Haglund E, Bremander A, Bergman S, Jacobsson LT, Petersson IF. Work productivity in a population-based cohort of patients with spondyloarthritis. Rheumatology (Oxford). 2013;52:1708–14.CrossRef Haglund E, Bremander A, Bergman S, Jacobsson LT, Petersson IF. Work productivity in a population-based cohort of patients with spondyloarthritis. Rheumatology (Oxford). 2013;52:1708–14.CrossRef
12.
go back to reference Strombeck B, Englund M, Bremander A, Jacobsson LT, Kedza L, Kobelt G, et al. Cost of illness from the public payers’ perspective in patients with ankylosing spondylitis in rheumatological care. J Rheumatol. 2010;37:2348–55.CrossRefPubMed Strombeck B, Englund M, Bremander A, Jacobsson LT, Kedza L, Kobelt G, et al. Cost of illness from the public payers’ perspective in patients with ankylosing spondylitis in rheumatological care. J Rheumatol. 2010;37:2348–55.CrossRefPubMed
13.
go back to reference McDonald M, DiBonaventura M, Ullman S. Musculoskeletal pain in the workforce: the effects of back, arthritis, and fibromyalgia pain on quality of life and work productivity. J Occup Environ Med. 2011;53:765–70.CrossRefPubMed McDonald M, DiBonaventura M, Ullman S. Musculoskeletal pain in the workforce: the effects of back, arthritis, and fibromyalgia pain on quality of life and work productivity. J Occup Environ Med. 2011;53:765–70.CrossRefPubMed
14.
go back to reference Burton WN, Chen CY, Schultz AB, Conti DJ, Pransky G, Edington DW. Worker productivity loss associated with arthritis. Dis Manag. 2006;9:131–43.CrossRefPubMed Burton WN, Chen CY, Schultz AB, Conti DJ, Pransky G, Edington DW. Worker productivity loss associated with arthritis. Dis Manag. 2006;9:131–43.CrossRefPubMed
15.
go back to reference Schultz AB, Edington DW. Employee health and presenteeism: a systematic review. J Occup Rehabil. 2007;17:547–79.CrossRefPubMed Schultz AB, Edington DW. Employee health and presenteeism: a systematic review. J Occup Rehabil. 2007;17:547–79.CrossRefPubMed
16.
go back to reference van der Burg LR, Ter Wee MM, Boonen A. Effect of biological therapy on work participation in patients with ankylosing spondylitis: a systematic review. Ann Rheum Dis. 2012;71:1924–33.CrossRefPubMed van der Burg LR, Ter Wee MM, Boonen A. Effect of biological therapy on work participation in patients with ankylosing spondylitis: a systematic review. Ann Rheum Dis. 2012;71:1924–33.CrossRefPubMed
17.
go back to reference Healey EL, Haywood KL, Jordan KP, Garratt A, Packham JC. Impact of ankylosing spondylitis on work in patients across the UK. Scand J Rheumatol. 2011;40:34–40.CrossRefPubMed Healey EL, Haywood KL, Jordan KP, Garratt A, Packham JC. Impact of ankylosing spondylitis on work in patients across the UK. Scand J Rheumatol. 2011;40:34–40.CrossRefPubMed
18.
go back to reference Maksymowych WP, Gooch KL, Wong RL, Kupper H, van der Heijde D. Impact of age, sex, physical function, health-related quality of life, and treatment with adalimumab on work status and work productivity of patients with ankylosing spondylitis. J Rheumatol. 2010;37:385–92.CrossRefPubMed Maksymowych WP, Gooch KL, Wong RL, Kupper H, van der Heijde D. Impact of age, sex, physical function, health-related quality of life, and treatment with adalimumab on work status and work productivity of patients with ankylosing spondylitis. J Rheumatol. 2010;37:385–92.CrossRefPubMed
19.
go back to reference Rafia R, Ara R, Packham J, Haywood KL, Healey E. Healthcare costs and productivity losses directly attributable to ankylosing spondylitis. Clin Exp Rheumatol. 2012;30:246–53.PubMed Rafia R, Ara R, Packham J, Haywood KL, Healey E. Healthcare costs and productivity losses directly attributable to ankylosing spondylitis. Clin Exp Rheumatol. 2012;30:246–53.PubMed
20.
go back to reference Reilly MC, Gooch KL, Wong RL, Kupper H, van der Heijde D. Validity, reliability and responsiveness of the Work Productivity and Activity Impairment Questionnaire in ankylosing spondylitis. Rheumatology (Oxford). 2010;49:812–9.CrossRef Reilly MC, Gooch KL, Wong RL, Kupper H, van der Heijde D. Validity, reliability and responsiveness of the Work Productivity and Activity Impairment Questionnaire in ankylosing spondylitis. Rheumatology (Oxford). 2010;49:812–9.CrossRef
21.
go back to reference Barlow JH, Wright CC, Williams B, Keat A. Work disability among people with ankylosing spondylitis. Arthritis Rheum. 2001;45:424–9.CrossRefPubMed Barlow JH, Wright CC, Williams B, Keat A. Work disability among people with ankylosing spondylitis. Arthritis Rheum. 2001;45:424–9.CrossRefPubMed
22.
go back to reference Boonen A, van Berkel M, Cieza A, Stucki G, van der Heijde D. Which aspects of functioning are relevant for patients with ankylosing spondylitis: results of focus group interviews. J Rheumatol. 2009;36:2501–11.CrossRefPubMed Boonen A, van Berkel M, Cieza A, Stucki G, van der Heijde D. Which aspects of functioning are relevant for patients with ankylosing spondylitis: results of focus group interviews. J Rheumatol. 2009;36:2501–11.CrossRefPubMed
23.
go back to reference Wikstrom I, Jacobsson LT. Change in and predictors of leisure activities among patients with rheumatoid arthritis: a prospective study. Scand J Rheumatol. 2005;34:367–71.CrossRefPubMed Wikstrom I, Jacobsson LT. Change in and predictors of leisure activities among patients with rheumatoid arthritis: a prospective study. Scand J Rheumatol. 2005;34:367–71.CrossRefPubMed
24.
go back to reference Englund M, Joud A, Geborek P, Felson DT, Jacobsson LT, Petersson IF. Prevalence and incidence of rheumatoid arthritis in southern Sweden 2008 and their relation to prescribed biologics. Rheumatology (Oxford). 2010;49:1563–9.CrossRef Englund M, Joud A, Geborek P, Felson DT, Jacobsson LT, Petersson IF. Prevalence and incidence of rheumatoid arthritis in southern Sweden 2008 and their relation to prescribed biologics. Rheumatology (Oxford). 2010;49:1563–9.CrossRef
25.
go back to reference Haglund E, Bergman S, Petersson IF, Jacobsson LT, Strombeck B, Bremander A. Differences in physical activity patterns in patients with spondylarthritis. Arthritis Care Res (Hoboken). 2012;64:1886–94.CrossRef Haglund E, Bergman S, Petersson IF, Jacobsson LT, Strombeck B, Bremander A. Differences in physical activity patterns in patients with spondylarthritis. Arthritis Care Res (Hoboken). 2012;64:1886–94.CrossRef
26.
go back to reference Prasad M, Wahlqvist P, Shikiar R, Shih YC. A review of self-report instruments measuring health-related work productivity: a patient-reported outcomes perspective. Pharmacoeconomics. 2004;22:225–44.CrossRefPubMed Prasad M, Wahlqvist P, Shikiar R, Shih YC. A review of self-report instruments measuring health-related work productivity: a patient-reported outcomes perspective. Pharmacoeconomics. 2004;22:225–44.CrossRefPubMed
27.
go back to reference Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993;4:353–65.CrossRefPubMed Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993;4:353–65.CrossRefPubMed
28.
go back to reference TheEuroQulGroup. EuroQol—a new facility for the measurement of health-Related Quality of Life. 1990;16(3):199–208. TheEuroQulGroup. EuroQol—a new facility for the measurement of health-Related Quality of Life. 1990;16(3):199–208.
29.
go back to reference Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol. 1994;21:2286–91.PubMed Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol. 1994;21:2286–91.PubMed
30.
go back to reference Calin A, Garrett S, Whitelock H, Kennedy LG, O’Hea J, Mallorie P, et al. A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol. 1994;21:2281–5.PubMed Calin A, Garrett S, Whitelock H, Kennedy LG, O’Hea J, Mallorie P, et al. A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol. 1994;21:2281–5.PubMed
31.
go back to reference Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–70.CrossRefPubMed Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–70.CrossRefPubMed
32.
go back to reference Lorig K, Chastain RL, Ung E, Shoor S, Holman HR. Development and evaluation of a scale to measure perceived self-efficacy in people with arthritis. Arthritis Rheum. 1989;32:37–44.CrossRefPubMed Lorig K, Chastain RL, Ung E, Shoor S, Holman HR. Development and evaluation of a scale to measure perceived self-efficacy in people with arthritis. Arthritis Rheum. 1989;32:37–44.CrossRefPubMed
33.
go back to reference Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007;39:1423–34.CrossRefPubMed Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007;39:1423–34.CrossRefPubMed
36.
go back to reference van der Heijde D, Han C, DeVlam K, Burmester G, van den Bosch F, Williamson P, et al. Infliximab improves productivity and reduces workday loss in patients with ankylosing spondylitis: results from a randomized, placebo-controlled trial. Arthritis Rheum. 2006;55:569–74.CrossRefPubMed van der Heijde D, Han C, DeVlam K, Burmester G, van den Bosch F, Williamson P, et al. Infliximab improves productivity and reduces workday loss in patients with ankylosing spondylitis: results from a randomized, placebo-controlled trial. Arthritis Rheum. 2006;55:569–74.CrossRefPubMed
37.
go back to reference Rohekar S, Pope J. Assessment of work disability in seronegative spondyloarthritis. Clin Exp Rheumatol. 2010;28:35–40.PubMed Rohekar S, Pope J. Assessment of work disability in seronegative spondyloarthritis. Clin Exp Rheumatol. 2010;28:35–40.PubMed
38.
go back to reference Ward MM, Kuzis S. Risk factors for work disability in patients with ankylosing spondylitis. J Rheumatol. 2001;28:315–21.PubMed Ward MM, Kuzis S. Risk factors for work disability in patients with ankylosing spondylitis. J Rheumatol. 2001;28:315–21.PubMed
39.
go back to reference Ward MM. Health-related quality of life in ankylosing spondylitis: a survey of 175 patients. Arthritis Care Res. 1999;12:247–55.CrossRefPubMed Ward MM. Health-related quality of life in ankylosing spondylitis: a survey of 175 patients. Arthritis Care Res. 1999;12:247–55.CrossRefPubMed
40.
go back to reference Hagstromer M, Ainsworth BE, Oja P, Sjostrom M. Comparison of a subjective and an objective measure of physical activity in a population sample. J Phys Act Health. 2010;7(4):541–50.PubMed Hagstromer M, Ainsworth BE, Oja P, Sjostrom M. Comparison of a subjective and an objective measure of physical activity in a population sample. J Phys Act Health. 2010;7(4):541–50.PubMed
41.
go back to reference Ward MM, Learch TJ, Gensler LS, Davis JC Jr, Reveille JD, Weisman MH. Regional radiographic damage and functional limitations in patients with ankylosing spondylitis: differences in early and late disease. Arthritis Care Res (Hoboken). 2013;65:257–65.CrossRef Ward MM, Learch TJ, Gensler LS, Davis JC Jr, Reveille JD, Weisman MH. Regional radiographic damage and functional limitations in patients with ankylosing spondylitis: differences in early and late disease. Arthritis Care Res (Hoboken). 2013;65:257–65.CrossRef
Metadata
Title
Predictors of Presenteeism and Activity Impairment Outside Work in Patients with Spondyloarthritis
Authors
Emma Haglund
Ingemar F. Petersson
Ann Bremander
Stefan Bergman
Publication date
01-06-2015
Publisher
Springer US
Published in
Journal of Occupational Rehabilitation / Issue 2/2015
Print ISSN: 1053-0487
Electronic ISSN: 1573-3688
DOI
https://doi.org/10.1007/s10926-014-9537-2

Other articles of this Issue 2/2015

Journal of Occupational Rehabilitation 2/2015 Go to the issue