Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Journal of Medical Systems
Published in: Journal of Medical Systems 1/2019

01-01-2019 | Patient Facing Systems

Association Between TG-to-HDL-C Ratio and In-Stent Stenosis Under Optical Coherence Tomography Guidance

Authors: Ya Li, Peng Jin, Fangjie Hou, Yujie Zhou

Published in: Journal of Medical Systems | Issue 1/2019

Login to get access

Abstract

We determined the relevance between the TG-to-HDL-C ratio and stent restenosis. Ninety-nine patients with in-stent stenosis (ISR) who were admitted to An Zhen Hospital in Beijing between April 2014 and June 2017 were selected. At the same time, 122 patients with coronary stenosis <50% were selected. All patients were tested for TG, HDL-C, and TG/HDL-C ratio. Optical coherence tomography (OCT) can assess microscopic status in all ISR patients. The proportion of male and Diabetic patients were significantly higher for ISR. There were differences in the prevalence of cigarette smokers among the different tissue types, among which the layered tissue type accounted for the highest proportion. In logistic regression analysis the study showed that male, diabetes mellitus, and the TG/HDL-C ratio are risk factors for ISR. The ISR ROC was 0.725 based on the TG/HDL-C ratio diagnosis. It is related to the degree of coronary stenosis and effective in diagnosing in-stent stenosis in ISR.
Literature
1.
Mintz, G. S., Clinical utility of intravascular imaging and physiology in coronary artery disease. J. Am. Coll. Cardiol. 64(2):207–221, 2014.CrossRef
2.
Nakano, M., Vorpahl, M., Otsuka, F. et al., Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging. JACC Cardiovasc. Imag. 5:71–82, 2012.CrossRef
3.
Onat, A., Can, G., Kaya, H. et al., “Atherogenic index of plasma”(log10 triglyceride/high-density lipoprotein-cholesterol) predicts high blood pressure, diabetes, and vascular events. J. Clin. Lipidol. 4(2):89–98, 2010.CrossRef
4.
Yunke, Z., Guoping, L., and Zhenyue, C., Triglyceride-to-HDL cholesterol ratio : Predictive value for CHD severity and new-onset heart failure. Herz. 39(1):105–110, 2014.CrossRef
5.
Shim, Y. S., Baek, J. W., Kang, M. J. et al., Reference Values for The Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Non-High-Density Lipoprotein Cholesterol in Korean Children and Adolescents: The Korean National Health and Nutrition Examination Surveys 2007–2013. J. Atheroscler. Thrombosis. 23(12):1334–1344, 2016.CrossRef
6.
Kasai, T., Miyauchi, K., Yanagisawa, N. et al., Mortality risk of triglyceride levels in patients with coronary artery disease. Heart. 99(1):22–29, 2013.CrossRef
7.
Davide, P., Cimino, G., Buccheri, D. et al., Recurrent in-stent restenosis, certainty of its origin, uncertainty about treatment. Int. J. Cardiol. 230:91–96, 2017.CrossRef
8.
Kundi, H., Korkmaz, A., Balun, A. et al., Is in-stent restenosis after a successful coronary stent implantation due to stable angina associated with TG/HDL-C ratio? Angiology. 68(9):816–822, 2017.CrossRef
9.
Yokoyama, K., Tani, S., Matsuo, R. et al., Increased triglyceride/high-density lipoprotein cholesterol ratio may be associated with reduction in the low-density lipoprotein particle size: Assessment of atherosclerotic cardiovascular disease risk. Heart Vessels, 2018. https://​doi.​org/​10.​1007/​s00380-018-1247-9.
10.
Murguıa-Romero, M., Jimenez-Flores, J. R., Sigrist-Flores, S. C. et al., Plasma triglyceride/HDL-cholesterol ratio, insulin resistance, and cardiometabolic risk in young adults. J. Lipid Res. 54(10):2795–2799, 2013.CrossRef
11.
Kang, H.-T., Yoon, J.-H., Kim, J.-Y. et al., The association between the ratio of triglyceride to HDL-C and insulin resistance according to waist circumference in a rural Korean population. Nutr. Metab. Cardiovasc. Dis. 22(12):1054–1060, 2012.CrossRef
12.
Ke, W., Zhao, J., Huang, H. et al., The association between triglyceride/high-density lipoprotein cholesterol ratio and all-cause mortality in acute coronary syndrome after coronary revascularization. PLoS ONE. 10(4):e0123521, 2015.CrossRef
13.
Farrell, S. W., Finley, C. E., Barlow, C. E. et al., Moderate to high levels of cardiorespiratory fitness attenuate the effects of triglyceride to high-density lipoprotein cholesterol ratio on coronary heart disease mortality in men. Mayo Clin. Proc. 92(12):1763–1771, 2017.CrossRef
14.
Kwon, Y.-J., Park, J.-W., Lim, H.-J. et al., Triglyceride to high density lipoprotein cholesterol ratio and its association with periodontal disease in Korean adults: Findings based on the 2012–2014 Korean national health and nutrition examination survey. Clin. Oral Investig. 5:1–8, 2017.
15.
Sarwer, N., Sandbu, M. S., Ricketts, S. L. et al., Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies. Lancet. 375(9726):1634–1639, 2010.CrossRef
16.
Hadaegh, F., Khalili, D., Ghasemi, A. et al., Triglyceride/HDL-cholesterol ratio is an independent predictor for coronary heart disease in a population of Iranian men. Nutr. Metab. Cardiovasc. Dis. 19(6):401–408, 2009.CrossRef
17.
Salazar, M. R., Carbajal, H. A., Espeche, W. G. et al., Use of the plasma triglyceride/high-density lipoprotein cholesterol ratio to identify cardiovascular disease in hypertensive subjects. J. Am. Soc. Hypertens. 8(10):724–731, 2014.CrossRef
18.
Tanaka, F., Makita, S., Onoda, T. et al., Predictive value of lipoprotein indices for residual risk of acute myocardial infarction and sudden death in men with low-density lipoprotein cholesterol levels< 120 mg/dl. Am. J. Cardio. 112(8):1063–1068, 2013.CrossRef
19.
Uthoff, H., Staub, D., Socrates, T. et al., PROCAM-FRAMING-HAM-SCORE-and SMART-risk score for predicting cardiovascular morbidity and mortality in patients with overt atherosclerosis. Vasa. 39(4):325–333, 2010.CrossRef
20.
Otakea, H., Shitea, J., Ikenob, F. et al., Evaluation of the peri-strut low intensity area following sirolimus and paclitaxel eluting stent implantion: Insignts from an optial coherence tomography study in human. Int. J. Cardiol. 157:38–42, 2012.CrossRef
21.
Malle, C., Tada, T., Steigerwald, K. et al., Tissue characterization after drug eluting stent implantation using optial coherence tomography. Arterioscler. Thromb. Vasc. Biol. 33:1376–1383, 2013.CrossRef
22.
Nagai, H., Ishibashi-ueda, H., and Fujll, K., Histology of highly echolucent regions in optial coherence tomography images from two patients with sirolimus eluting stent restenosis. Catheter Cardiovasc. Interv. 75:961–963, 2010.
23.
Zhang, B. C., Karanasos, A., and Regar, E., OCT demonstrating neoatherosclerosis as part of the continuous process of coronary artery disease. Herz. 40:845–854, 2015.CrossRef
24.
Kim, J. S., Afari, M. E., Ha, J. et al., Neointimal patterns obtained by optial coherence tomography with specific histological components and neointimal proliferation in a swine model of restenosis. Eur. Heart J. Cardiovasc. Imag. 15:292–298, 2014.CrossRef
25.
Kim, J. S., Hong, M. K., Shin, D. H. et al., Quantitative and qualitative changes in DES-related neointimal tissue based on serial OCT. JACC Cardiovasc. Imag. 5:1147–1155, 2012.CrossRef
26.
Kufener, S., Cassese, S., Valeskini, M. et al., Long-term efficacy and safety of paclitaxel-eluting balloon for the treatment of drug-eluting stent restenosis: 3-year results of a randomized controlled trial. JACC Cardiovasc. Interv. 8(7):877–884, 2015.CrossRef
27.
Tada, T., Kadota, K., Hosogi, S. et al., Association between tissue characteristics assessed with optical coherence tomography and mid-term results after percutaneous coronary intervention for in-stent restenosis. Lesions: a comparison between balloon angioplasty, paclitaxel-coated balloon dilatation, and drug-eluting stent implantation. Eur. Heart J. Cardiovasc. Imag. 16(10):1101–1111, 2015.CrossRef
Metadata
Title
Association Between TG-to-HDL-C Ratio and In-Stent Stenosis Under Optical Coherence Tomography Guidance
Authors
Ya Li
Peng Jin
Fangjie Hou
Yujie Zhou
Publication date
01-01-2019
Publisher
Springer US
Published in
Journal of Medical Systems / Issue 1/2019
Print ISSN: 0148-5598
Electronic ISSN: 1573-689X
DOI
https://doi.org/10.1007/s10916-018-1119-y

Other articles of this Issue 1/2019

Journal of Medical Systems 1/2019 Go to the issue

Mobile & Wireless Health

A Robust and Efficient ECC-based Mutual Authentication and Session Key Generation Scheme for Healthcare Applications

Correction

Correction to: An Extended Hackathon Model for Collaborative Education in Medical Innovation

Systems-Level Quality Improvement

Extracting Interesting Rules from Gestation Course Data for Early Diagnosis of Neonatal Hypoxia

Image & Signal Processing

LS-GSNO and CWSNO Enhancement Processes Using PCA Algorithm with LOOCV of R-SM Technique for Effective Face Recognition Approach

Systems-Level Quality Improvement

Healthcare Data Breaches: Implications for Digital Forensic Readiness

Systems-Level Quality Improvement

IoT-Based Services and Applications for Mental Health in the Literature