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Published in: Journal of Mammary Gland Biology and Neoplasia 2/2013

Open Access 01-06-2013

Prenatal Morphogenesis of Mammary Glands in Mouse and Rabbit

Authors: Alain Y. Propper, Beatrice A. Howard, Jacqueline M. Veltmaat

Published in: Journal of Mammary Gland Biology and Neoplasia | Issue 2/2013

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Abstract

Our understanding of prenatal morphogenesis of mammary glands has recently greatly advanced. This review focuses on morphogenesis proper, as well as cellular processes and tissue interactions involved in the progression of the embryonic mammary gland through sequential morphogenic stages in both the mouse and rabbit embryo. We provide a synthesis of both historical and more recent studies of embryonic mammary gland development, as well as arguments to revise old concepts about mechanisms of mammary line and rudiment formation. Finally, we highlight outstanding issues that remain to be addressed.
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Metadata
Title
Prenatal Morphogenesis of Mammary Glands in Mouse and Rabbit
Authors
Alain Y. Propper
Beatrice A. Howard
Jacqueline M. Veltmaat
Publication date
01-06-2013
Publisher
Springer US
Published in
Journal of Mammary Gland Biology and Neoplasia / Issue 2/2013
Print ISSN: 1083-3021
Electronic ISSN: 1573-7039
DOI
https://doi.org/10.1007/s10911-013-9298-0

Other articles of this Issue 2/2013

Journal of Mammary Gland Biology and Neoplasia 2/2013 Go to the issue
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Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

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