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Published in: Journal of Clinical Monitoring and Computing 3/2012

01-06-2012

Pulse oximeter plethysmograph variation and its relationship to the arterial waveform in mechanically ventilated children

Authors: J. R. Chandler, E. Cooke, C. Petersen, W. Karlen, N. Froese, J. Lim, J. M. Ansermino

Published in: Journal of Clinical Monitoring and Computing | Issue 3/2012

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Abstract

The variations induced by mechanical ventilation in the arterial pulse pressure and pulse oximeter plethysmograph waveforms have been shown to correlate closely and be effective in adults as markers of volume responsiveness. The aims of our study were to investigate: (1) the feasibility of recording plethysmograph indices; and (2) the relationship between pulse pressure variation (ΔPP), plethysmograph variation (ΔPOP) and plethysmograph variability index (PVI) in a diverse group of mechanically ventilated children. A prospective, observational study was performed. Mechanically ventilated children less than 11 years of age, with arterial catheters, were enrolled during the course of their clinical care in the operating room or in the pediatric intensive care unit. Real time monitor waveforms and trend data were recorded. ΔPP and ΔPOP were manually calculated and the relationships between ΔPP, ΔPOP and PVI were compared using Bland–Altman analysis and Pearson correlations. Forty-nine children were recruited; four (8%) subjects were excluded due to poor quality of the plethysmograph waveforms. ΔPP and ΔPOP demonstrated a strong correlation (r = 0.8439, P < 0.0001) and close agreement (Bias = 1.44 ± 6.4%). PVI was found to correlate strongly with ΔPP (r = 0.7049, P < 0.0001) and ΔPOP (r = 0.715, P < 0.0001). This study demonstrates the feasibility of obtaining plethysmographic variability indices in children under various physiological stresses. These data show a similarly strong correlation to that described in adults, between the variations induced by mechanical ventilation in arterial pulse pressure and the pulse oximeter plethysmograph.
Literature
1.
go back to reference Brierley J, Carcillo JA, Choong K, Cornell T, Decaen A, et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med. 2009;37(2):666–88. doi:10.1097/CCM.0b013e31819323c6.PubMedCrossRef Brierley J, Carcillo JA, Choong K, Cornell T, Decaen A, et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med. 2009;37(2):666–88. doi:10.​1097/​CCM.​0b013e31819323c6​.PubMedCrossRef
3.
go back to reference Tibby SM, Hatherill M, Durward A, Murdoch IA. Are transoesophageal Doppler parameters a reliable guide to paediatric haemodynamic status and fluid management? Intensive Care Med. 2001;27(1):201–5. doi:10.1007/s001340000795.PubMedCrossRef Tibby SM, Hatherill M, Durward A, Murdoch IA. Are transoesophageal Doppler parameters a reliable guide to paediatric haemodynamic status and fluid management? Intensive Care Med. 2001;27(1):201–5. doi:10.​1007/​s001340000795.PubMedCrossRef
4.
go back to reference Kumar A, Anel R, Bunnell E, Habet K, Zanotti S, Marshall S, Neumann A, Ali A, Cheang M, Kavinsky C, Parrillo JE. Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects. Crit Care Med. 2004;32(3):691–9. doi:10.1097/01.CCM.0000114996.68110.C9.PubMedCrossRef Kumar A, Anel R, Bunnell E, Habet K, Zanotti S, Marshall S, Neumann A, Ali A, Cheang M, Kavinsky C, Parrillo JE. Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects. Crit Care Med. 2004;32(3):691–9. doi:10.​1097/​01.​CCM.​0000114996.​68110.​C9.PubMedCrossRef
5.
go back to reference Feissel M, Michard F, Mangin I, Ruyer O, Faller JP, Teboul JL. Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock. Chest. 2001;119(3):867–73. doi:10.1378/chest.119.3.867.PubMedCrossRef Feissel M, Michard F, Mangin I, Ruyer O, Faller JP, Teboul JL. Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock. Chest. 2001;119(3):867–73. doi:10.​1378/​chest.​119.​3.​867.PubMedCrossRef
6.
go back to reference Michard F, Boussat S, Chemla D, Anguel N, Mercat A, Lecarpentier Y, Richard C, Pinsky MR, Teboul JL. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med. 2000;162(1):134–8.PubMed Michard F, Boussat S, Chemla D, Anguel N, Mercat A, Lecarpentier Y, Richard C, Pinsky MR, Teboul JL. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med. 2000;162(1):134–8.PubMed
7.
go back to reference Reuter DA, Felbinger TW, Schmidt C, Kilger E, Goedje O, Lamm P, Goetz AE. Stroke volume variations for assessment of cardiac responsiveness to volume loading in mechanically ventilated patients after cardiac surgery. Intensive Care Med. 2002;28(4):392–8. doi:10.1007/s00134-002-1211-z.PubMedCrossRef Reuter DA, Felbinger TW, Schmidt C, Kilger E, Goedje O, Lamm P, Goetz AE. Stroke volume variations for assessment of cardiac responsiveness to volume loading in mechanically ventilated patients after cardiac surgery. Intensive Care Med. 2002;28(4):392–8. doi:10.​1007/​s00134-002-1211-z.PubMedCrossRef
9.
go back to reference Choi DY, Kwak HJ, Park HY, Kim YB, Choi CH, Lee JY. Respiratory variation in aortic blood flow velocity as a predictor of fluid responsiveness in children after repair of ventricular septal defect. Pediatr Cardiol. 2010;31(8):1166–70. doi:10.1007/s00246-010-9776-8.PubMedCrossRef Choi DY, Kwak HJ, Park HY, Kim YB, Choi CH, Lee JY. Respiratory variation in aortic blood flow velocity as a predictor of fluid responsiveness in children after repair of ventricular septal defect. Pediatr Cardiol. 2010;31(8):1166–70. doi:10.​1007/​s00246-010-9776-8.PubMedCrossRef
10.
go back to reference de Souza Pereira, Neto E, Grousson S, Duflo F, Ducreux C, Joly H, Convert J, Mottolese C, Dailler F, Cannesson M. Predicting fluid responsiveness in mechanically ventilated children under general anaesthesia using dynamic parameters and transthoracic echocardiography. Br J Anaesth. 2011;106(6):856–64. doi:10.1093/bja/aer090.CrossRef de Souza Pereira, Neto E, Grousson S, Duflo F, Ducreux C, Joly H, Convert J, Mottolese C, Dailler F, Cannesson M. Predicting fluid responsiveness in mechanically ventilated children under general anaesthesia using dynamic parameters and transthoracic echocardiography. Br J Anaesth. 2011;106(6):856–64. doi:10.​1093/​bja/​aer090.CrossRef
12.
go back to reference Cannesson M, Besnard C, Durand PG, Bohe J, Jacques D. Relation between respiratory variations in pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure in ventilated patients. Crit Care. 2005;9(5):R562–8. doi:10.1186/cc3799.PubMedCrossRef Cannesson M, Besnard C, Durand PG, Bohe J, Jacques D. Relation between respiratory variations in pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure in ventilated patients. Crit Care. 2005;9(5):R562–8. doi:10.​1186/​cc3799.PubMedCrossRef
13.
go back to reference Cannesson M, Delannoy B, Morand A, Rosamel P, Attof Y, Bastien O, Lehot JJ. Does the Pleth variability index indicate the respiratory-induced variation in the plethysmogram and arterial pressure waveforms? Anesth Analg. 2008;106(4):1189–94. doi:10.1213/ane.0b013e318167ab1f.PubMedCrossRef Cannesson M, Delannoy B, Morand A, Rosamel P, Attof Y, Bastien O, Lehot JJ. Does the Pleth variability index indicate the respiratory-induced variation in the plethysmogram and arterial pressure waveforms? Anesth Analg. 2008;106(4):1189–94. doi:10.​1213/​ane.​0b013e318167ab1f​.PubMedCrossRef
15.
16.
go back to reference Cannesson M, Desebbe O, Rosamel P, Delannoy B, Robin J, Bastien O, Lehot JJ. Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre. Br J Anaesth. 2008;101(2):200–6. doi:10.1093/bja/aen133.PubMedCrossRef Cannesson M, Desebbe O, Rosamel P, Delannoy B, Robin J, Bastien O, Lehot JJ. Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre. Br J Anaesth. 2008;101(2):200–6. doi:10.​1093/​bja/​aen133.PubMedCrossRef
18.
go back to reference Chemla D, Hebert JL, Coirault C, Zamani K, Suard I, Colin P, Lecarpentier Y. Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans. Am J Physiol. 1998;274(2 Pt 2):H500–5.PubMed Chemla D, Hebert JL, Coirault C, Zamani K, Suard I, Colin P, Lecarpentier Y. Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans. Am J Physiol. 1998;274(2 Pt 2):H500–5.PubMed
20.
21.
go back to reference Papastamelos C, Panitch HB, England SE, Allen JL. Developmental changes in chest wall compliance in infancy and early childhood. J Appl Physiol. 1995;78(1):179–84.PubMed Papastamelos C, Panitch HB, England SE, Allen JL. Developmental changes in chest wall compliance in infancy and early childhood. J Appl Physiol. 1995;78(1):179–84.PubMed
23.
go back to reference Euliano N, Meka V, Melker R, Fuehrlein B (2005) Pulse oximetry data acquisition viewer (PODAV)—New Plethysmograph Processing Software. Society for Technology in Anesthesia Annual Meeting Abstracts Euliano N, Meka V, Melker R, Fuehrlein B (2005) Pulse oximetry data acquisition viewer (PODAV)—New Plethysmograph Processing Software. Society for Technology in Anesthesia Annual Meeting Abstracts
24.
go back to reference McCanne S, Jacobson V (1993) The BSD packet filter: a new architecture for user-level packet capture. In: Proceedings of the USENIX Winter 1993 conference:2 McCanne S, Jacobson V (1993) The BSD packet filter: a new architecture for user-level packet capture. In: Proceedings of the USENIX Winter 1993 conference:2
25.
go back to reference Desebbe O, Boucau C, Farhat F, Bastien O, Lehot JJ, Cannesson M. The ability of pleth variability index to predict the hemodynamic effects of positive end-expiratory pressure in mechanically ventilated patients under general anesthesia. Anesth Analg. 2010;110(3):792–8. doi:10.1213/ANE.0b013e3181cd6d06.PubMedCrossRef Desebbe O, Boucau C, Farhat F, Bastien O, Lehot JJ, Cannesson M. The ability of pleth variability index to predict the hemodynamic effects of positive end-expiratory pressure in mechanically ventilated patients under general anesthesia. Anesth Analg. 2010;110(3):792–8. doi:10.​1213/​ANE.​0b013e3181cd6d06​.PubMedCrossRef
26.
go back to reference Michard F, Teboul JL. Using heart-lung interactions to assess fluid responsiveness during mechanical ventilation. Crit Care. 2000;4(5):282–9.PubMedCrossRef Michard F, Teboul JL. Using heart-lung interactions to assess fluid responsiveness during mechanical ventilation. Crit Care. 2000;4(5):282–9.PubMedCrossRef
27.
go back to reference Berkenstadt H, Margalit N, Hadani M, Friedman Z, Segal E, Villa Y, Perel A. Stroke volume variation as a predictor of fluid responsiveness in patients undergoing brain surgery. Anesth Analg. 2001;92(4):984–9.PubMedCrossRef Berkenstadt H, Margalit N, Hadani M, Friedman Z, Segal E, Villa Y, Perel A. Stroke volume variation as a predictor of fluid responsiveness in patients undergoing brain surgery. Anesth Analg. 2001;92(4):984–9.PubMedCrossRef
30.
go back to reference Renner J, Broch O, Duetschke P, Scheewe J, Höcker J, Moseby M, Jung O, Bein B. Prediction of fluid responsiveness in infants and neonates undergoing congenital heart surgery. British J Anaesth. 2012;108(1):108–15. doi:10.1093/bja/aer371.CrossRef Renner J, Broch O, Duetschke P, Scheewe J, Höcker J, Moseby M, Jung O, Bein B. Prediction of fluid responsiveness in infants and neonates undergoing congenital heart surgery. British J Anaesth. 2012;108(1):108–15. doi:10.​1093/​bja/​aer371.CrossRef
Metadata
Title
Pulse oximeter plethysmograph variation and its relationship to the arterial waveform in mechanically ventilated children
Authors
J. R. Chandler
E. Cooke
C. Petersen
W. Karlen
N. Froese
J. Lim
J. M. Ansermino
Publication date
01-06-2012
Publisher
Springer Netherlands
Published in
Journal of Clinical Monitoring and Computing / Issue 3/2012
Print ISSN: 1387-1307
Electronic ISSN: 1573-2614
DOI
https://doi.org/10.1007/s10877-012-9347-z

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