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Journal of Clinical Immunology
Published in: Journal of Clinical Immunology 5/2021

01-07-2021 | Secondary Immunodeficiency | Letter to Editor

Resolution of Persistent COVID-19 After Convalescent Plasma in a Patient with B Cell Aplasia

Authors: Emily McKemey, Adrian M. Shields, Sian E. Faustini, Harriet J. Hill, Aliaksandra Barnskaya, Zania Stamataki, Simon Gompertz, Alex G. Richter, Davinder Dosanjh, Shyam Madathil

Published in: Journal of Clinical Immunology | Issue 5/2021

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Excerpt

To the Editor, …
Appendix
Available only for authorised users
Literature
1.
London J, et al. Severe COVID-19 in patients with B cell alymphocytosis and response to convalescent plasma therapy. J Clin Immunol. 2021;41(2):356–61.
2.
Shields AM et al. COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience. J Allergy Clin Immunol. 2020;S0091–6749(20)32406-4.
3.
Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, et al. Remdesivir for the treatment of Covid-19 - final report. N Engl J Med. 2020;383(19):1813–26.CrossRef
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RECOVERY Collaborative Group et al. Dexamethasone in hospitalized patients with covid-19 - Preliminary report. N Engl J Med. 2020.
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Simonovich VA et al. A randomized trial of convalescent plasma in covid-19 severe pneumonia. N Engl J Med 2021;384:619–29.
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Gordon CJ, Tchesnokov EP, Woolner E, Perry JK, Feng JY, Porter DP, et al. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency. J Biol Chem. 2020;295(20):6785–97.CrossRef
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Meyts I et al. Coronavirus disease 2019 in patients with inborn errors of immunity: An international study. J Allergy Clin Immunol. 2021;147(2):520–31.
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Hueso T, Pouderoux C, Péré H, Beaumont AL, Raillon LA, Ader F, et al. Convalescent plasma therapy for B-cell-depleted patients with protracted COVID-19. Blood. 2020;136(20):2290–5.CrossRef
9.
Jin H, et al. Three patients with X-linked agammaglobulinemia hospitalized for COVID-19 improved with convalescent plasma. J Allergy Clin Immunol Pract. 2020;8(10):3594–3596.e3.CrossRef
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Buckland MS, et al. Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report. Nat Commun. 2020;11(1):6385.CrossRef
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Van Damme KFA, et al. Case report: convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19. Front Immunol. 2020;11:596761.CrossRef
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Schwaiger J, Karbiener M, Aberham C, Farcet MR, Kreil TR. No SARS-CoV-2 neutralization by intravenous Immunoglobulins produced from plasma collected before the 2020 pandemic. J Infect Dis. 2020;222(12):1960–4.CrossRef
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Kemp SA, et al. Neutralising antibodies in spike mediated SARS-CoV-2 adaptation. medRxiv, 2020: p. 2020.12.05.20241927.
Metadata
Title
Resolution of Persistent COVID-19 After Convalescent Plasma in a Patient with B Cell Aplasia
Authors
Emily McKemey
Adrian M. Shields
Sian E. Faustini
Harriet J. Hill
Aliaksandra Barnskaya
Zania Stamataki
Simon Gompertz
Alex G. Richter
Davinder Dosanjh
Shyam Madathil
Publication date
01-07-2021
Publisher
Springer US
Published in
Journal of Clinical Immunology / Issue 5/2021
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI
https://doi.org/10.1007/s10875-021-00996-7

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