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01-07-2020 | Expert Opinion | Letter to Editor

The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery

Authors: Tri Giang Phan, Paul E. Gray, Melanie Wong, Rebecca Macintosh, Leslie Burnett, Stuart G. Tangye, on behalf of CIRCA

Published in: Journal of Clinical Immunology | Issue 5/2020

Abstract

The Clinical Immunogenomics Research Consortium Australasia (CIRCA) crowdsources expertise in medicine, genomics, data science, and fundamental biology to diagnose and treat patients with rare inborn errors of immunity. This distributed network model operates free of geographic borders and allows rapid progression through the full research/translation/clinical management pipeline, from initial gene variant discovery, through functional validation, and on to precision mechanism-based treatment of patients throughout Australia and New Zealand. The model is scalable and applicable to other rare diseases where clinical experience and scientific know-how are limited, and enables efficient delivery of genomics for all.

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Title: The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery
Authors: Tri Giang Phan
Paul E. Gray
Melanie Wong
Rebecca Macintosh
Leslie Burnett
Stuart G. Tangye
on behalf of CIRCA
Publication date: 01-07-2020
Publisher: Springer US
Keywords: Expert Opinion
Expert Opinion
Published in: Journal of Clinical Immunology / Issue 5/2020
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-020-00787-6

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