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01-05-2017 | Letter to Editor

Low IgA and IgM Is Associated with a Higher Prevalence of Bronchiectasis in Primary Antibody Deficiency

Authors: John P. Hodkinson, Catherine Bangs, Andrea Wartenberg-Demand, Artur Bauhofer, Patrick Langohr, Matthew S. Buckland, David Guzman, Patrick F. K. Yong, Sorena Kiani-Alikhan

Published in: Journal of Clinical Immunology | Issue 4/2017

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To the Editor, …

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Gathmann B, Mahlaoui N, Ceredih GL, Oksenhendler E, Warnatz K, et al. Clinical picture and treatment of 2212 patients with common variable immunodeficiency. J Allergy Clin Immunol. 2014;134(1):116–26.CrossRefPubMed

Kiani-Alikhan S, Yong PF, Grosse-Kreul D, Elston C, Ibrahim MA. Immunoglobulin replacement therapy: is there a role for IgA and IgM? J Allergy Clin Immunol. 2012;130(2):553–4. author reply 4CrossRefPubMed

Quinti I, Soresina A, Guerra A, Rondelli R, Spadaro G, Agostini C, et al. Effectiveness of immunoglobulin replacement therapy on clinical outcome in patients with primary antibody deficiencies: results from a multicenter prospective cohort study. J Clin Immunol. 2011;31(3):315–22.CrossRefPubMed

Cerutti A, Chen K, Chorny A. Immunoglobulin responses at the mucosal interface. Annu Rev Immunol. 2011;29:273–93.CrossRefPubMedPubMedCentral

Lucas M, Lee M, Lortan J, Lopez-Granados E, Misbah S, Chapel H. Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years. J Allergy Clin Immunol. 2010;125(6):1354–60. e4CrossRefPubMed

Verma N, Grimbacher B, Hurst JR. Lung disease in primary antibody deficiency. Lancet Respir Med. 2015;3(8):651–60.CrossRefPubMed

A Milford Ward, J Sheldon, A Rowbottom and GD Wild. Protein Reference Unit Handbook in Clinical Immunochemistry 2007 (9th Edition).

Cavaliere FM, Milito C, Martini H, Schlesier M, Drager R, Schutz K, et al. Quantification of IgM and IgA anti-pneumococcal capsular polysaccharides by a new ELISA assay: a valuable diagnostic and prognostic tool for common variable immunodeficiency. J Clin Immunol. 2013;33(4):838–46.CrossRefPubMed

Title: Low IgA and IgM Is Associated with a Higher Prevalence of Bronchiectasis in Primary Antibody Deficiency
Authors: John P. Hodkinson
Catherine Bangs
Andrea Wartenberg-Demand
Artur Bauhofer
Patrick Langohr
Matthew S. Buckland
David Guzman
Patrick F. K. Yong
Sorena Kiani-Alikhan
Publication date: 01-05-2017
Publisher: Springer US
Published in: Journal of Clinical Immunology / Issue 4/2017
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-017-0381-y

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