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Journal of Clinical Immunology

Published in:

01-05-2008

Autoinflammatory Diseases: Mimics of Autoimmunity or Part of its Spectrum? Case Presentation

Authors: Maria Helena B. Kiss, Claudia Saad Magalhães

Published in: Journal of Clinical Immunology | Special Issue 1/2008

Abstract

Introduction:

Autoinflammatory diseases are very rare diseases presenting within a wide clinical spectrum. Recognition of the main clinical features are challenging due to overlapping or mimicking with autoimmune diseases.

Discussion:

A case series is reviewed to illustrate typical and atypical features and the difficulties of these diagnoses in the low prevalence areas—a typical unrecognized case of familial Mediterranean fever (FMF) in a youngster, an atypical adult case with overlapping of FMF with Behçet disease, and an early presentation of FMF in infant presenting with inflammatory colitis, as well as the overlapping features within the cryopirin diseases spectrum in an 8-year-old boy who presented with systemic onset arthritis.

Conclusion:

These cases may represent examples of a very puzzling relationship among disorders of innate and adaptive immune systems and inflammation.

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Title: Autoinflammatory Diseases: Mimics of Autoimmunity or Part of its Spectrum? Case Presentation
Authors: Maria Helena B. Kiss
Claudia Saad Magalhães
Publication date: 01-05-2008
Publisher: Springer US
Published in: Journal of Clinical Immunology / Issue Special Issue 1/2008
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-008-9179-2

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Conclusion:

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