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Journal of Assisted Reproduction and Genetics

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01-04-2019 | Letter to the Editor

Observation of two separate bipolar spindles in the human zygote

Authors: Xiaoming Xu, Linheng Li, Chuilian Zhang, Li Meng

Published in: Journal of Assisted Reproduction and Genetics | Issue 4/2019

Excerpt

Dear Editor-in-Chief: …

Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider I, Politi AZ, et al. Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos. Science (New York, NY). 2018;361:189–93.CrossRef

Kai Y, Moriwaki H, Yumoto K, Iwata K, Mio Y. Assessment of developmental potential of human single pronucleated zygotes derived from conventional in vitro fertilization. J Assist Reprod Genet. 2018;35:1377–84.CrossRefPubMedPubMedCentral

Mayer W, Smith A, Fundele R, Haaf T. Spatial separation of parental genomes in preimplantation mouse embryos. J Cell Biol. 2000;148:629–34.CrossRefPubMedPubMedCentral

Destouni A, Vermeesch JR (2017) How can zygotes segregate entire parental genomes into distinct blastomeres? The zygote metaphase revisited. Bioessays 39(4). https://doi.org/10.1002/bies.201600226

Albertini DF. Making sense out of syngamy at the onset of mammalian development. J Assist Reprod Genet. 2018;35:1357–8.CrossRefPubMedPubMedCentral

Paulson RJ. The unscientific nature of the concept that “human life begins at fertilization,” and why it matters. Fertil Steril. 2017;107:566–7.CrossRefPubMed

Title: Observation of two separate bipolar spindles in the human zygote
Authors: Xiaoming Xu
Linheng Li
Chuilian Zhang
Li Meng
Publication date: 01-04-2019
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 4/2019
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-019-01440-x

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