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Journal of Assisted Reproduction and Genetics

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01-12-2017 | Commentary

At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care

Authors: Piraye Yurttas Beim, David-Emlyn Parfitt, Lei Tan, Elaine A. Sugarman, Tina Hu-Seliger, Caterina Clementi, Brynn Levy

Published in: Journal of Assisted Reproduction and Genetics | Issue 12/2017

Excerpt

Advances in genomics are revolutionizing how diseases are prevented, diagnosed, and treated, across all fields of medicine. In reproductive medicine, genomic technologies are used for carrier, embryo, and prenatal screening. However, to date, genetic information has not been widely utilized for guiding treatment decisions or identifying individuals at risk for reproductive conditions, including those that can lead to infertility and early menopause. In contrast, analysis of genetic biomarkers is now the standard of care in oncology [1]. Today, oncologists routinely categorize tumors based on genetic signatures and refine their treatment strategies accordingly. This targeted approach to more personalized treatment has led to significantly higher progression-free survival rates when compared to the outcomes of conventional therapies [2]. Knowledge of patients’ genetic risk factors has also decreased patient morbidity and mortality by more precisely revealing individuals who would benefit from preventative cancer screenings such as colonoscopies or mammograms. …

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Title: At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care
Authors: Piraye Yurttas Beim
David-Emlyn Parfitt
Lei Tan
Elaine A. Sugarman
Tina Hu-Seliger
Caterina Clementi
Brynn Levy
Publication date: 01-12-2017
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 12/2017
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-017-1068-2

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

At the dawn of personalized reproductive medicine: opportunities and challenges with incorporating multigene panel testing into fertility care

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Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

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