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Published in: Journal of Assisted Reproduction and Genetics 12/2010

01-12-2010 | Assisted Reproduction Technologies

Opinion

How should we define success in assisted reproduction? Is live birth rate the gold standard measurement?

Authors: Ulun Ulug, Izhar Ben-Shlomo, Mustafa Bahceci

Published in: Journal of Assisted Reproduction and Genetics | Issue 12/2010

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Excerpt

The dictionary defines “success” as the favorable or prosperous result of attempts or endeavors. This definition is too simplistic at times, especially as it relates to assisted reproduction technologies (ART). Currently, there is a consensus that live birth rates are the best measurement to assess the success of ART. This is evidenced by the multitude of scientific papers reporting on the success of ART using live birth rate as the outcome measure. …
Literature
1.
go back to reference Steptoe PC, Edwards RG. Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet. 1976;1:880–2.CrossRefPubMed Steptoe PC, Edwards RG. Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet. 1976;1:880–2.CrossRefPubMed
2.
go back to reference Dessolle L, Fréour T, Barrière P, Jean M, Ravel C, Daraï E, Biau DJ. How soon can I be proficient in embryo transfer? Lessons from the cumulative summation test for learning curve (LC-CUSUM). Hum Reprod. 2010;380–6. Dessolle L, Fréour T, Barrière P, Jean M, Ravel C, Daraï E, Biau DJ. How soon can I be proficient in embryo transfer? Lessons from the cumulative summation test for learning curve (LC-CUSUM). Hum Reprod. 2010;380–6.
3.
go back to reference Ulug U, Jozwiak EA, Mesut A, Berksoy MM, Bahceci M. Survival rates during the first trimester of multiple gestations achieved by ICSI: a report of 1448 consecutive multiples. Hum Reprod. 2005;19:360–4.CrossRef Ulug U, Jozwiak EA, Mesut A, Berksoy MM, Bahceci M. Survival rates during the first trimester of multiple gestations achieved by ICSI: a report of 1448 consecutive multiples. Hum Reprod. 2005;19:360–4.CrossRef
4.
go back to reference Kolibianakis EM, Kalogeropoulou L, Griesinger G, Papanikolaou EG, Papadimas J, Bontis J, et al. Among patients treated with FSH and GnRH analogues for in vitro fertilization, is the addition of recombinant LH associated with the probability of live birth? A systematic review and meta-analysis. Hum Reprod Updat. 2007;13:445–52.CrossRef Kolibianakis EM, Kalogeropoulou L, Griesinger G, Papanikolaou EG, Papadimas J, Bontis J, et al. Among patients treated with FSH and GnRH analogues for in vitro fertilization, is the addition of recombinant LH associated with the probability of live birth? A systematic review and meta-analysis. Hum Reprod Updat. 2007;13:445–52.CrossRef
5.
go back to reference Kolibianakis EM, Collins J, Tarlatzis BC, Devroey P, Diedrich K, Griesinger G. Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Updat. 2006;12:651–71.CrossRef Kolibianakis EM, Collins J, Tarlatzis BC, Devroey P, Diedrich K, Griesinger G. Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Updat. 2006;12:651–71.CrossRef
6.
go back to reference Coomarasamy A, Afnan M, Cheema D, van der Veen F, Bossuyt PM, van Wely M. Urinary hMG versus recombinant FSH for controlled ovarian hyperstimulation following an agonist long down-regulation protocol in IVF or ICSI treatment: a systematic review and meta-analysis. Hum Reprod. 2008;23:310–5.CrossRefPubMed Coomarasamy A, Afnan M, Cheema D, van der Veen F, Bossuyt PM, van Wely M. Urinary hMG versus recombinant FSH for controlled ovarian hyperstimulation following an agonist long down-regulation protocol in IVF or ICSI treatment: a systematic review and meta-analysis. Hum Reprod. 2008;23:310–5.CrossRefPubMed
7.
go back to reference Al-Inany HG, Abou-Setta AM, Aboulghar MA, Mansour RT, Serour GI. Efficacy and safety of human menopausal gonadotrophins versus recombinant FSH: a meta-analysis. Reprod Biomed Online. 2008;16:81–8.CrossRefPubMed Al-Inany HG, Abou-Setta AM, Aboulghar MA, Mansour RT, Serour GI. Efficacy and safety of human menopausal gonadotrophins versus recombinant FSH: a meta-analysis. Reprod Biomed Online. 2008;16:81–8.CrossRefPubMed
8.
go back to reference Daya S, Gunby J. Luteal phase support in assisted reproduction cycles. Cochrane Database Syst Rev. 2004;3:CD004830.PubMed Daya S, Gunby J. Luteal phase support in assisted reproduction cycles. Cochrane Database Syst Rev. 2004;3:CD004830.PubMed
9.
go back to reference Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology 2009. Fertil Steril. 2009;92:1520–4.CrossRefPubMed Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology 2009. Fertil Steril. 2009;92:1520–4.CrossRefPubMed
Metadata
Title
Opinion
How should we define success in assisted reproduction? Is live birth rate the gold standard measurement?
Authors
Ulun Ulug
Izhar Ben-Shlomo
Mustafa Bahceci
Publication date
01-12-2010
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 12/2010
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-010-9472-x

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