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Journal of Assisted Reproduction and Genetics

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01-04-2010 | Technical Innovations

Clinical outcomes resulting from the transfer of vitrified human embryos using a new device for cryopreservation (plastic blade)

Authors: Rikikazu Sugiyama, Koji Nakagawa, Asako Shirai, Rie Sugiyama, Yayoi Nishi, Yasushi Kuribayashi, Masato Inoue

Published in: Journal of Assisted Reproduction and Genetics | Issue 4/2010

Abstract

Purpose

We attempted clinical application of a plastic blade, which is a novel cryopreservation device, for vitrification of human embryos and blastocysts.

Methods

Between February 2003 and December 2007, a total of 4,430 Day 3 embryos from 898 patients (Day 3 group) and 55 blastocysts from 29 patients (blastocyst group) were vitrified and cryopreserved with a plastic device, and subsequently thawed for embryo transfer. Clinical outcomes after thawing and transfer of vitrified embryos and blastocysts were evaluated.

Results

In the Day 3 group, all embryos resulting from 1,441 oocyte retrieval cycles were recovered, and the thawed embryo survival rate was 98.4%. In the blastocyst group, the survival rate after thawing was 100%. A total of 3,026 day 3 embryos and 46 blastocysts were transferred. The pregnancy and implantation rates in the Day 3 group were 25.0% and 15.5%, respectively, and in the blastocyst group the rates were 24.2% and 26.1%, respectively. The miscarriage rates in the Day 3 and blastocyst groups were 18.3% and 50.0%, respectively.

Conclusions

A plastic blade is a useful novel device in cryopreservation of vitrified human embryos.

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Title: Clinical outcomes resulting from the transfer of vitrified human embryos using a new device for cryopreservation (plastic blade)
Authors: Rikikazu Sugiyama
Koji Nakagawa
Asako Shirai
Rie Sugiyama
Yayoi Nishi
Yasushi Kuribayashi
Masato Inoue
Publication date: 01-04-2010
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 4/2010
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-010-9390-y

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Clinical outcomes resulting from the transfer of vitrified human embryos using a new device for cryopreservation (plastic blade)

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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