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01-04-2020 | Original Paper

Corneal biomechanics in different age groups

Authors: Ahmed Abdel Karim El Massry, Amr Ahmed Said, Ihab Mohamed Osman, Amr Saad Bessa, Mohammed Ahmed Elmasry, Eman Nabil Elsayed, Nader Hussein Lotfy Bayoumi

Published in: International Ophthalmology | Issue 4/2020

Abstract

Purpose

To report on the corneal biomechanical characteristics, namely the corneal hysteresis (CH), corneal resistance factor (CRF), as well as the intraocular pressure (IOP) goldman compensated (IOPg), and the cornea compensated (IOPcc), using the ocular response analyzer (ORA) in different age groups in a cohort of normal individuals from the second decade to the seventh decade and beyond.

Patients and methods

The study was a cross-sectional survey conducted on 997 eyes of 508 normal individuals presenting for a routine ophthalmic examination at Alexandria Main University Hospital in Alexandria University, Alexandria, Egypt. The study subjects were age stratified into decades (10–20, 21–30, 31–40, 41–50, > 50) and the ORA parameters (CH, CRF, IOPg, IOPcc) reported and stratified. Correlations were sought between the ORA parameters and the age, gender, and laterality.

Results

The study was conducted on 997 (502 right) eyes of 508 (234 males) normal individuals. The mean ± SD ages of the study groups were 14.7 ± 3.2, 25.9 ± 3.0, 35.3 ± 2.8, 44.6 ± 2.9, and 61.1 ± 7.7 years. The mean ± SD of the CH in the study groups were 10.9 ± 2.4, 9.8 ± 1.5, 9.8 ± 1.4, 9.7 ± 1.7, and 9.5 ± 1.6 mmHg and of the CRF were 10.9 ± 2.4, 9.5 ± 1.7, 9.4 ± 1.8, 9.6 ± 1.9, and 9.6 ± 1.8 mmHg. A statistically significant negative correlation was found between age and each of CH and CRF. IOPcc demonstrated a fairly constant trend in the different age groups whereas IOPg demonstrated an initial decline followed by a gradual rise over time.

Conclusion

The corneal biomechanical properties CH and CRF decrease with age. IOPg and IOPcc change minimally with age.

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Title: Corneal biomechanics in different age groups
Authors: Ahmed Abdel Karim El Massry
Amr Ahmed Said
Ihab Mohamed Osman
Amr Saad Bessa
Mohammed Ahmed Elmasry
Eman Nabil Elsayed
Nader Hussein Lotfy Bayoumi
Publication date: 01-04-2020
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 4/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-019-01273-8

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Corneal biomechanics in different age groups

Abstract

Purpose

Patients and methods

Results

Conclusion

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Purpose

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Results

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