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Published in: International Ophthalmology 4/2019

01-04-2019 | Cryotherapy | Review

Recent advances in the diagnosis and treatment of Coats’ disease

Published in: International Ophthalmology | Issue 4/2019

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Abstract

Purpose

To review and summarize the recent progress in the diagnosis and treatment of Coats’ disease.

Methods

Literature was collected from Web of Science, Medline and Pubmed, through searching of these keywords: “Coats’ disease”, “diagnosis” and “treatment”.

Results

Coats’ disease is characterized by idiopathic leaky retinal vascular telangiectasia and microvascular abnormalities often accompanied by intraretinal or subretinal exudation and retinal detachment. Neovascular glaucoma and phthisis bulbi often occur in advanced cases. Coats’ disease has significant diversity in terms of its clinical presentation and morphology. Anti-VEGF therapy combined with laser photocoagulation for early Coats’ disease and anti-VEGF therapy combined with minimally invasive vitrectomy for advanced Coats’ disease can achieve good efficacy.

Conclusion

Early diagnosis and timely treatment based on clinical stage are critical to retaining the patient’s visual function. Patients should be aware that close long-term follow-up is necessary.
Literature
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Metadata
Title
Recent advances in the diagnosis and treatment of Coats’ disease
Publication date
01-04-2019
Published in
International Ophthalmology / Issue 4/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-019-01095-8

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