Skip to main content
Top
Published in: Heart Failure Reviews 3/2012

01-05-2012

Right side of heart failure

Authors: Maya Guglin, Sameer Verma

Published in: Heart Failure Reviews | Issue 3/2012

Login to get access

Abstract

The function of the right ventricle (RV) in heart failure (HF) has been mostly ignored until recently. A 2006 report of the National Heart, Lung, and Blood Institute identified a gap between RV research efforts and its clinical importance compared with that of the left ventricle. This recent shift in paradigm is fueled by the prognostic value ascribed to RV failure in HF and morbidity/mortality after myocardial infarction and surgery. In this review, we examine the significance of RV failure in the HF setting, its clinical presentation and pathophysiology, and ways to evaluate RV function using echocardiographic measurements. Furthermore, we discuss the medical management of RV failure including traditional therapies like beta-blockers and newer options like nitric oxide, phosphodiesterase inhibitors, and calcium sensitizers. Mechanical support is also examined. Finally, this review places an emphasis on RV failure in the setting of left ventricular assist devices and heart transplantation.
Literature
1.
go back to reference Lindenfeld J, Albert NM, Boehmer JP et al (2010) HFSA 2010 comprehensive heart failure practice guideline. J Card Fail 16:e1–e194PubMedCrossRef Lindenfeld J, Albert NM, Boehmer JP et al (2010) HFSA 2010 comprehensive heart failure practice guideline. J Card Fail 16:e1–e194PubMedCrossRef
2.
go back to reference Starr I, Jeffers W, Meade R (1943) The absence of conspicuous increments of venous pressure after severe damage to the RV of the dog, with discussion of the relation between clinical congestive heart failure and heart disease. Am Heart J 26:291–301CrossRef Starr I, Jeffers W, Meade R (1943) The absence of conspicuous increments of venous pressure after severe damage to the RV of the dog, with discussion of the relation between clinical congestive heart failure and heart disease. Am Heart J 26:291–301CrossRef
3.
go back to reference Voelkel NF, Quaife RA, Leinwand LA et al (2006) Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation 114:1883–1891PubMedCrossRef Voelkel NF, Quaife RA, Leinwand LA et al (2006) Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation 114:1883–1891PubMedCrossRef
4.
5.
go back to reference Haddad F, Ashley E, Michelakis ED (2010) New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy. Curr Opin Cardiol 25:131–140 Haddad F, Ashley E, Michelakis ED (2010) New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy. Curr Opin Cardiol 25:131–140
6.
go back to reference Woods J, Monteiro P, Rhodes A (2007) Right ventricular dysfunction. Curr Opin Crit Care 13:532–540PubMed Woods J, Monteiro P, Rhodes A (2007) Right ventricular dysfunction. Curr Opin Crit Care 13:532–540PubMed
7.
go back to reference Ghio S, Recusani F, Klersy C et al (2000) Prognostic usefulness of the tricuspid annular plane systolic excursion in patients with congestive heart failure secondary to idiopathic or ischemic dilated cardiomyopathy. Am J Cardiol 85:837–842PubMedCrossRef Ghio S, Recusani F, Klersy C et al (2000) Prognostic usefulness of the tricuspid annular plane systolic excursion in patients with congestive heart failure secondary to idiopathic or ischemic dilated cardiomyopathy. Am J Cardiol 85:837–842PubMedCrossRef
8.
go back to reference Kjaergaard J, Akkan D, Iversen KK, Kober L, Torp-Pedersen C, Hassager C (2007) Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failure. Eur J Heart Fail 9:610–616PubMedCrossRef Kjaergaard J, Akkan D, Iversen KK, Kober L, Torp-Pedersen C, Hassager C (2007) Right ventricular dysfunction as an independent predictor of short- and long-term mortality in patients with heart failure. Eur J Heart Fail 9:610–616PubMedCrossRef
9.
go back to reference Meluzin J, Spinarova L, Dusek L, Toman J, Hude P, Krejci J (2003) Prognostic importance of the right ventricular function assessed by Doppler tissue imaging. Eur J Echocardiogr 4:262–271PubMedCrossRef Meluzin J, Spinarova L, Dusek L, Toman J, Hude P, Krejci J (2003) Prognostic importance of the right ventricular function assessed by Doppler tissue imaging. Eur J Echocardiogr 4:262–271PubMedCrossRef
10.
go back to reference Verhaert D, Mullens W, Borowski AG et al. (2010) Right ventricular response to intensive medical therapy in advanced decompensated heart failure. Circ Heart Fail 3(3):340–346 Verhaert D, Mullens W, Borowski AG et al. (2010) Right ventricular response to intensive medical therapy in advanced decompensated heart failure. Circ Heart Fail 3(3):340–346
11.
go back to reference La Vecchia L, Zanolla L, Varotto L et al (2001) Reduced right ventricular ejection fraction as a marker for idiopathic dilated cardiomyopathy compared with ischemic left ventricular dysfunction. Am Heart J 142:181–189PubMedCrossRef La Vecchia L, Zanolla L, Varotto L et al (2001) Reduced right ventricular ejection fraction as a marker for idiopathic dilated cardiomyopathy compared with ischemic left ventricular dysfunction. Am Heart J 142:181–189PubMedCrossRef
12.
go back to reference Juilliere Y, Barbier G, Feldmann L, Grentzinger A, Danchin N, Cherrier F (1997) Additional predictive value of both left and right ventricular ejection fractions on long-term survival in idiopathic dilated cardiomyopathy. Eur Heart J 18:276–280PubMed Juilliere Y, Barbier G, Feldmann L, Grentzinger A, Danchin N, Cherrier F (1997) Additional predictive value of both left and right ventricular ejection fractions on long-term survival in idiopathic dilated cardiomyopathy. Eur Heart J 18:276–280PubMed
13.
go back to reference Otasevic P, Popovic Z, Pratali L, Vlahovic A, Vasiljevic JD, Neskovic AN (2005) Right vs. left ventricular contractile reserve in one-year prognosis of patients with idiopathic dilated cardiomyopathy: assessment by dobutamine stress echocardiography. Eur J Echocardiogr 6:429–434PubMedCrossRef Otasevic P, Popovic Z, Pratali L, Vlahovic A, Vasiljevic JD, Neskovic AN (2005) Right vs. left ventricular contractile reserve in one-year prognosis of patients with idiopathic dilated cardiomyopathy: assessment by dobutamine stress echocardiography. Eur J Echocardiogr 6:429–434PubMedCrossRef
14.
go back to reference Sun JP, James KB, Yang XS et al (1997) Comparison of mortality rates and progression of left ventricular dysfunction in patients with idiopathic dilated cardiomyopathy and dilated versus nondilated right ventricular cavities. Am J Cardiol 80:1583–1587PubMedCrossRef Sun JP, James KB, Yang XS et al (1997) Comparison of mortality rates and progression of left ventricular dysfunction in patients with idiopathic dilated cardiomyopathy and dilated versus nondilated right ventricular cavities. Am J Cardiol 80:1583–1587PubMedCrossRef
15.
go back to reference Anavekar NS, Skali H, Bourgoun M et al (2008) Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study). Am J Cardiol 101:607–612PubMedCrossRef Anavekar NS, Skali H, Bourgoun M et al (2008) Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study). Am J Cardiol 101:607–612PubMedCrossRef
16.
go back to reference Samad BA, Alam M, Jensen-Urstad K (2002) Prognostic impact of right ventricular involvement as assessed by tricuspid annular motion in patients with acute myocardial infarction. Am J Cardiol 90:778–781PubMedCrossRef Samad BA, Alam M, Jensen-Urstad K (2002) Prognostic impact of right ventricular involvement as assessed by tricuspid annular motion in patients with acute myocardial infarction. Am J Cardiol 90:778–781PubMedCrossRef
17.
go back to reference Zornoff LA, Skali H, Pfeffer MA et al (2002) Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol 39:1450–1455PubMedCrossRef Zornoff LA, Skali H, Pfeffer MA et al (2002) Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol 39:1450–1455PubMedCrossRef
18.
go back to reference Antoni ML, Scherptong RW, Atary JZ et al. (2010) Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Circ Cardiovasc Imag 3(3):264–271 Antoni ML, Scherptong RW, Atary JZ et al. (2010) Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Circ Cardiovasc Imag 3(3):264–271
19.
go back to reference Dini FL, Conti U, Fontanive P et al (2007) Right ventricular dysfunction is a major predictor of outcome in patients with moderate to severe mitral regurgitation and left ventricular dysfunction. Am Heart J 154:172–179PubMedCrossRef Dini FL, Conti U, Fontanive P et al (2007) Right ventricular dysfunction is a major predictor of outcome in patients with moderate to severe mitral regurgitation and left ventricular dysfunction. Am Heart J 154:172–179PubMedCrossRef
20.
go back to reference Nunes Mdo C, Rocha MO, Ribeiro AL et al (2008) Right ventricular dysfunction is an independent predictor of survival in patients with dilated chronic Chagas’ cardiomyopathy. Int J Cardiol 127:372–379PubMedCrossRef Nunes Mdo C, Rocha MO, Ribeiro AL et al (2008) Right ventricular dysfunction is an independent predictor of survival in patients with dilated chronic Chagas’ cardiomyopathy. Int J Cardiol 127:372–379PubMedCrossRef
21.
go back to reference Haddad F, Couture P, Tousignant C, Denault AY (2009) The right ventricle in cardiac surgery, a perioperative perspective: II. Pathophysiology, clinical importance, and management. Anesth Analg 108:422–433PubMedCrossRef Haddad F, Couture P, Tousignant C, Denault AY (2009) The right ventricle in cardiac surgery, a perioperative perspective: II. Pathophysiology, clinical importance, and management. Anesth Analg 108:422–433PubMedCrossRef
22.
go back to reference Puwanant S, Priester TC, Mookadam F, Bruce CJ, Redfield MM, Chandrasekaran K (2009) Right ventricular function in patients with preserved and reduced ejection fraction heart failure. Eur J Echocardiogr 10:733–737PubMedCrossRef Puwanant S, Priester TC, Mookadam F, Bruce CJ, Redfield MM, Chandrasekaran K (2009) Right ventricular function in patients with preserved and reduced ejection fraction heart failure. Eur J Echocardiogr 10:733–737PubMedCrossRef
23.
go back to reference Meluzin J, Spinarova L, Hude P et al (2005) Combined right ventricular systolic and diastolic dysfunction represents a strong determinant of poor prognosis in patients with symptomatic heart failure. Int J Cardiol 105:164–173PubMedCrossRef Meluzin J, Spinarova L, Hude P et al (2005) Combined right ventricular systolic and diastolic dysfunction represents a strong determinant of poor prognosis in patients with symptomatic heart failure. Int J Cardiol 105:164–173PubMedCrossRef
24.
go back to reference Meluzin J, Spinarova L, Hude P et al (2005) Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure. J Am Soc Echocardiogr 18:435–444PubMedCrossRef Meluzin J, Spinarova L, Hude P et al (2005) Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure. J Am Soc Echocardiogr 18:435–444PubMedCrossRef
25.
go back to reference Ghio S, Gavazzi A, Campana C et al (2001) Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure. J Am Coll Cardiol 37:183–188PubMedCrossRef Ghio S, Gavazzi A, Campana C et al (2001) Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure. J Am Coll Cardiol 37:183–188PubMedCrossRef
26.
go back to reference Guglin M, Rivero A, Matar F, Garcia M (2011) Renal dysfunction in heart failure is due to congestion but not low output. Clin Cardiol 34:113–116PubMedCrossRef Guglin M, Rivero A, Matar F, Garcia M (2011) Renal dysfunction in heart failure is due to congestion but not low output. Clin Cardiol 34:113–116PubMedCrossRef
27.
go back to reference Mullens W, Abrahams Z, Francis GS et al (2009) Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol 53:589–596PubMedCrossRef Mullens W, Abrahams Z, Francis GS et al (2009) Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol 53:589–596PubMedCrossRef
28.
go back to reference Testani JM, Khera AV, St John Sutton MG et al (2009) Effect of right ventricular function and venous congestion on cardiorenal interactions during the treatment of decompensated heart failure. Am J Cardiol 105:511–516CrossRef Testani JM, Khera AV, St John Sutton MG et al (2009) Effect of right ventricular function and venous congestion on cardiorenal interactions during the treatment of decompensated heart failure. Am J Cardiol 105:511–516CrossRef
29.
go back to reference Maeder MT, Holst DP, Kaye DM (2008) Tricuspid regurgitation contributes to renal dysfunction in patients with heart failure. J Card Fail 14:824–830PubMedCrossRef Maeder MT, Holst DP, Kaye DM (2008) Tricuspid regurgitation contributes to renal dysfunction in patients with heart failure. J Card Fail 14:824–830PubMedCrossRef
30.
go back to reference Wiener-Kronish JP, Berthiaume Y, Albertine KH (1985) Pleural effusions and pulmonary edema. Clin Chest Med 6:509–519PubMed Wiener-Kronish JP, Berthiaume Y, Albertine KH (1985) Pleural effusions and pulmonary edema. Clin Chest Med 6:509–519PubMed
31.
go back to reference Deffebach ME, Charan NB, Lakshminarayan S, Butler J (1987) The bronchial circulation. Small, but a vital attribute of the lung. Am Rev Respir Dis 135:463–481PubMed Deffebach ME, Charan NB, Lakshminarayan S, Butler J (1987) The bronchial circulation. Small, but a vital attribute of the lung. Am Rev Respir Dis 135:463–481PubMed
32.
go back to reference Stewart RH, Rohn DA, Allen SJ, Laine GA (1997) Basic determinants of epicardial transudation. Am J Physiol 273:H1408–H1414PubMed Stewart RH, Rohn DA, Allen SJ, Laine GA (1997) Basic determinants of epicardial transudation. Am J Physiol 273:H1408–H1414PubMed
33.
go back to reference Boulanger B, Yuan Z, Flessner M, Hay J, Johnston M (1999) Pericardial fluid absorption into lymphatic vessels in sheep. Microvasc Res 57:174–186PubMedCrossRef Boulanger B, Yuan Z, Flessner M, Hay J, Johnston M (1999) Pericardial fluid absorption into lymphatic vessels in sheep. Microvasc Res 57:174–186PubMedCrossRef
34.
go back to reference Laine GA, Allen SJ, Katz J, Gabel JC, Drake RE (1986) Effect of systemic venous pressure elevation on lymph flow and lung edema formation. J Appl Physiol 61:1634–1638PubMed Laine GA, Allen SJ, Katz J, Gabel JC, Drake RE (1986) Effect of systemic venous pressure elevation on lymph flow and lung edema formation. J Appl Physiol 61:1634–1638PubMed
35.
go back to reference Wiener-Kronish JP, Matthay MA, Callen PW, Filly RA, Gamsu G, Staub NC (1985) Relationship of pleural effusions to pulmonary hemodynamics in patients with congestive heart failure. Am Rev Respir Dis 132:1253–1256PubMed Wiener-Kronish JP, Matthay MA, Callen PW, Filly RA, Gamsu G, Staub NC (1985) Relationship of pleural effusions to pulmonary hemodynamics in patients with congestive heart failure. Am Rev Respir Dis 132:1253–1256PubMed
36.
go back to reference Wiener-Kronish JP, Matthay MA (1988) Pleural effusions associated with hydrostatic and increased permeability pulmonary edema. Chest 93:852–858PubMedCrossRef Wiener-Kronish JP, Matthay MA (1988) Pleural effusions associated with hydrostatic and increased permeability pulmonary edema. Chest 93:852–858PubMedCrossRef
37.
go back to reference Kinasewitz GT, Fishman AP (1981) Influence of alterations in Starling forces on visceral pleural fluid movement. J Appl Physiol 51:671–677PubMed Kinasewitz GT, Fishman AP (1981) Influence of alterations in Starling forces on visceral pleural fluid movement. J Appl Physiol 51:671–677PubMed
38.
go back to reference Allen SJ, Laine GA, Drake RE, Gabel JC (1988) Superior vena caval pressure elevation causes pleural effusion formation in sheep. Am J Physiol 255:H492–H495PubMed Allen SJ, Laine GA, Drake RE, Gabel JC (1988) Superior vena caval pressure elevation causes pleural effusion formation in sheep. Am J Physiol 255:H492–H495PubMed
39.
go back to reference Allen S, Gabel J, Drake R (1989) Left atrial hypertension causes pleural effusion formation in unanesthetized sheep. Am J Physiol 257:H690–H692PubMed Allen S, Gabel J, Drake R (1989) Left atrial hypertension causes pleural effusion formation in unanesthetized sheep. Am J Physiol 257:H690–H692PubMed
40.
go back to reference Broaddus VC, Wiener-Kronish JP, Staub NC (1990) Clearance of lung edema into the pleural space of volume-loaded anesthetized sheep. J Appl Physiol 68:2623–2630PubMed Broaddus VC, Wiener-Kronish JP, Staub NC (1990) Clearance of lung edema into the pleural space of volume-loaded anesthetized sheep. J Appl Physiol 68:2623–2630PubMed
41.
go back to reference Miller AJ, Pick R, Johnson PJ (1971) The production of acute pericardial effusion: the effects of various degrees of interference with venous blood and lymph drainage from the heart muscle in the dog. Am J Cardiol 28:463–466PubMedCrossRef Miller AJ, Pick R, Johnson PJ (1971) The production of acute pericardial effusion: the effects of various degrees of interference with venous blood and lymph drainage from the heart muscle in the dog. Am J Cardiol 28:463–466PubMedCrossRef
42.
go back to reference Mehlhorn U, Davis KL, Laine GA, Geissler HJ, Allen SJ (1996) Myocardial fluid balance in acute hypertension. Microcirculation 3:371–378PubMedCrossRef Mehlhorn U, Davis KL, Laine GA, Geissler HJ, Allen SJ (1996) Myocardial fluid balance in acute hypertension. Microcirculation 3:371–378PubMedCrossRef
43.
go back to reference Calvin JE Jr (1991) Acute right heart failure: pathophysiology, recognition, and pharmacological management. J Cardiothorac Vasc Anesth 5:507–513PubMedCrossRef Calvin JE Jr (1991) Acute right heart failure: pathophysiology, recognition, and pharmacological management. J Cardiothorac Vasc Anesth 5:507–513PubMedCrossRef
44.
go back to reference Redington AN (2006) Physiopathology of right ventricular failure. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 3–10 Redington AN (2006) Physiopathology of right ventricular failure. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 3–10
45.
go back to reference Cohen JA, Kaplan MM (1978) Left-sided heart failure presenting as hepatitis. Gastroenterology 74:583–587PubMed Cohen JA, Kaplan MM (1978) Left-sided heart failure presenting as hepatitis. Gastroenterology 74:583–587PubMed
46.
go back to reference Richman SM, Delman AJ, Grob D (1961) Alterations in indices of liver function in congestive heart failure with particular reference to serum enzymes. Am J Med 30:211–225PubMedCrossRef Richman SM, Delman AJ, Grob D (1961) Alterations in indices of liver function in congestive heart failure with particular reference to serum enzymes. Am J Med 30:211–225PubMedCrossRef
47.
go back to reference Ezzat WR, Lautt WW (1987) Hepatic arterial pressure-flow autoregulation is adenosine mediated. Am J Physiol 252:H836–H845PubMed Ezzat WR, Lautt WW (1987) Hepatic arterial pressure-flow autoregulation is adenosine mediated. Am J Physiol 252:H836–H845PubMed
48.
go back to reference Gitlin N, Serio KM (1992) Ischemic hepatitis: widening horizons. Am J Gastroenterol 87:831–836PubMed Gitlin N, Serio KM (1992) Ischemic hepatitis: widening horizons. Am J Gastroenterol 87:831–836PubMed
50.
go back to reference Nouel O, Henrion J, Bernuau J, Degott C, Rueff B, Benhamou JP (1980) Fulminant hepatic failure due to transient circulatory failure in patients with chronic heart disease. Dig Dis Sci 25:49–52PubMedCrossRef Nouel O, Henrion J, Bernuau J, Degott C, Rueff B, Benhamou JP (1980) Fulminant hepatic failure due to transient circulatory failure in patients with chronic heart disease. Dig Dis Sci 25:49–52PubMedCrossRef
51.
go back to reference Seeto RK, Fenn B, Rockey DC (2000) Ischemic hepatitis: clinical presentation and pathogenesis. Am J Med 109:109–113PubMedCrossRef Seeto RK, Fenn B, Rockey DC (2000) Ischemic hepatitis: clinical presentation and pathogenesis. Am J Med 109:109–113PubMedCrossRef
52.
go back to reference Kuramoto M, Yamane T, Ueno K, Kurasawa T, Matsumoto S, Kuribayashi N (1991) A case of fulminant hepatic failure secondary to congestive heart failure. Kokyu Junkan 39:607–611 Kuramoto M, Yamane T, Ueno K, Kurasawa T, Matsumoto S, Kuribayashi N (1991) A case of fulminant hepatic failure secondary to congestive heart failure. Kokyu Junkan 39:607–611
53.
go back to reference Pillarisetti J, Nath J, Berenbom L, Lakkireddy D (2010) Cardiac cirrhosis: a rare manifestation of an uncorrected primum atrial septal defect. J Cardiovasc Med (Hagerstown) 11:689–691CrossRef Pillarisetti J, Nath J, Berenbom L, Lakkireddy D (2010) Cardiac cirrhosis: a rare manifestation of an uncorrected primum atrial septal defect. J Cardiovasc Med (Hagerstown) 11:689–691CrossRef
54.
go back to reference van Lingen R, Warshow U, Dalton HR, Hussaini SH (2005) Jaundice as a presentation of heart failure. J R Soc Med 98:357–359PubMedCrossRef van Lingen R, Warshow U, Dalton HR, Hussaini SH (2005) Jaundice as a presentation of heart failure. J R Soc Med 98:357–359PubMedCrossRef
55.
go back to reference Bolger AP, Sharma R, Li W et al (2002) Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease. Circulation 106:92–99PubMedCrossRef Bolger AP, Sharma R, Li W et al (2002) Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease. Circulation 106:92–99PubMedCrossRef
56.
go back to reference Mulder P, Richard V, Derumeaux G et al (1997) Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling. Circulation 96:1976–1982PubMed Mulder P, Richard V, Derumeaux G et al (1997) Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling. Circulation 96:1976–1982PubMed
57.
go back to reference Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF (2009) The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 135:794–804PubMedCrossRef Bogaard HJ, Abe K, Vonk Noordegraaf A, Voelkel NF (2009) The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension. Chest 135:794–804PubMedCrossRef
58.
go back to reference Nagaya N, Nishikimi T, Uematsu M et al (2000) Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension. Circulation 102:865–870PubMed Nagaya N, Nishikimi T, Uematsu M et al (2000) Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension. Circulation 102:865–870PubMed
59.
go back to reference Sarnoff SJ, Berglund E (1954) Ventricular function. I. Starling’s law of the heart studied by means of simultaneous right and left ventricular function curves in the dog. Circulation 9:706–718PubMed Sarnoff SJ, Berglund E (1954) Ventricular function. I. Starling’s law of the heart studied by means of simultaneous right and left ventricular function curves in the dog. Circulation 9:706–718PubMed
60.
go back to reference Konstam MA, Salem DN, Isner JM et al (1984) Vasodilator effect on right ventricular function in congestive heart failure and pulmonary hypertension: end-systolic pressure–volume relation. Am J Cardiol 54:132–136PubMedCrossRef Konstam MA, Salem DN, Isner JM et al (1984) Vasodilator effect on right ventricular function in congestive heart failure and pulmonary hypertension: end-systolic pressure–volume relation. Am J Cardiol 54:132–136PubMedCrossRef
61.
go back to reference Mebazaa A, Karpati P, Renaud E, Algotsson L (2004) Acute right ventricular failure—from pathophysiology to new treatments. Intensive Care Med 30:185–196PubMedCrossRef Mebazaa A, Karpati P, Renaud E, Algotsson L (2004) Acute right ventricular failure—from pathophysiology to new treatments. Intensive Care Med 30:185–196PubMedCrossRef
62.
go back to reference Beppu S, Naito H, Matsuhisa M, Miyatake K, Nimura Y (1990) The effects of lying position on ventricular volume in congenital absence of the pericardium. Am Heart J 120:1159–1166PubMedCrossRef Beppu S, Naito H, Matsuhisa M, Miyatake K, Nimura Y (1990) The effects of lying position on ventricular volume in congenital absence of the pericardium. Am Heart J 120:1159–1166PubMedCrossRef
63.
go back to reference Schertz C, Pinsky MR (1993) Effect of the pericardium on systolic ventricular interdependence in the dog. J Crit Care 8:17–23PubMedCrossRef Schertz C, Pinsky MR (1993) Effect of the pericardium on systolic ventricular interdependence in the dog. J Crit Care 8:17–23PubMedCrossRef
64.
go back to reference Santamore WP, Dell’Italia LJ (1998) Ventricular interdependence: significant left ventricular contributions to right ventricular systolic function. Prog Cardiovasc Dis 40:289–308PubMedCrossRef Santamore WP, Dell’Italia LJ (1998) Ventricular interdependence: significant left ventricular contributions to right ventricular systolic function. Prog Cardiovasc Dis 40:289–308PubMedCrossRef
65.
go back to reference Jurcut R, Giusca S, La Gerche A, Vasile S, Ginghina C, Voigt JU (2010) The echocardiographic assessment of the right ventricle: what to do in 2010? Eur J Echocardiogr 11:81–96PubMedCrossRef Jurcut R, Giusca S, La Gerche A, Vasile S, Ginghina C, Voigt JU (2010) The echocardiographic assessment of the right ventricle: what to do in 2010? Eur J Echocardiogr 11:81–96PubMedCrossRef
66.
go back to reference Saleh S, Liakopoulos OJ, Buckberg GD (2006) The septal motor of biventricular function. Eur J Cardiothorac Surg 29(Suppl 1):S126–S138PubMedCrossRef Saleh S, Liakopoulos OJ, Buckberg GD (2006) The septal motor of biventricular function. Eur J Cardiothorac Surg 29(Suppl 1):S126–S138PubMedCrossRef
67.
go back to reference Plunkett MD, Buckberg GD (2007) Pathophysiologic implications of the helical ventricular myocardial band: considerations for right ventricular restoration. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 68–75 Plunkett MD, Buckberg GD (2007) Pathophysiologic implications of the helical ventricular myocardial band: considerations for right ventricular restoration. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 68–75
68.
go back to reference Yamaguchi S, Harasawa H, Li KS, Zhu D, Santamore WP (1991) Comparative significance in systolic ventricular interaction. Cardiovasc Res 25:774–783PubMedCrossRef Yamaguchi S, Harasawa H, Li KS, Zhu D, Santamore WP (1991) Comparative significance in systolic ventricular interaction. Cardiovasc Res 25:774–783PubMedCrossRef
69.
go back to reference Jurcut R, Giusca S, La Gerche A, Vasile S, Ginghina C, Voigt JU (2010) The echocardiographic assessment of the right ventricle: what to do in 2010? Eur J Echocardiogr 11:81–96PubMedCrossRef Jurcut R, Giusca S, La Gerche A, Vasile S, Ginghina C, Voigt JU (2010) The echocardiographic assessment of the right ventricle: what to do in 2010? Eur J Echocardiogr 11:81–96PubMedCrossRef
70.
go back to reference Drazner MH, Hamilton MA, Fonarow G, Creaser J, Flavell C, Stevenson LW (1999) Relationship between right and left-sided filling pressures in 1000 patients with advanced heart failure. J Heart Lung Transplant 18:1126–1132PubMedCrossRef Drazner MH, Hamilton MA, Fonarow G, Creaser J, Flavell C, Stevenson LW (1999) Relationship between right and left-sided filling pressures in 1000 patients with advanced heart failure. J Heart Lung Transplant 18:1126–1132PubMedCrossRef
71.
go back to reference Adamson PB, Magalski A, Braunschweig F et al (2003) Ongoing right ventricular hemodynamics in heart failure: clinical value of measurements derived from an implantable monitoring system. J Am Coll Cardiol 41:565–571PubMedCrossRef Adamson PB, Magalski A, Braunschweig F et al (2003) Ongoing right ventricular hemodynamics in heart failure: clinical value of measurements derived from an implantable monitoring system. J Am Coll Cardiol 41:565–571PubMedCrossRef
72.
go back to reference Arbulu A (2000) Trivalvular/bivalvular heart: a philosophical, scientific and therapeutic concept. J Heart Valve Dis 9:353–357, discussion 7–8 Arbulu A (2000) Trivalvular/bivalvular heart: a philosophical, scientific and therapeutic concept. J Heart Valve Dis 9:353–357, discussion 7–8
73.
go back to reference Kjaergaard J, Iversen KK, Akkan D et al (2009) Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure. Cardiovasc Ultrasound 7:51PubMedCrossRef Kjaergaard J, Iversen KK, Akkan D et al (2009) Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure. Cardiovasc Ultrasound 7:51PubMedCrossRef
74.
go back to reference Shiran A, Sagie A (2009) Tricuspid regurgitation in mitral valve disease incidence, prognostic implications, mechanism, and management. J Am Coll Cardiol 53:401–408PubMedCrossRef Shiran A, Sagie A (2009) Tricuspid regurgitation in mitral valve disease incidence, prognostic implications, mechanism, and management. J Am Coll Cardiol 53:401–408PubMedCrossRef
75.
go back to reference Szabo G, Soos P, Bahrle S et al (2006) Adaptation of the right ventricle to an increased afterload in the chronically volume overloaded heart. Ann Thorac Surg 82:989–995PubMedCrossRef Szabo G, Soos P, Bahrle S et al (2006) Adaptation of the right ventricle to an increased afterload in the chronically volume overloaded heart. Ann Thorac Surg 82:989–995PubMedCrossRef
76.
go back to reference Berisha S, Kastrati A, Goda A, Popa Y (1990) Optimal value of filling pressure in the right side of the heart in acute right ventricular infarction. Br Heart J 63:98–102PubMedCrossRef Berisha S, Kastrati A, Goda A, Popa Y (1990) Optimal value of filling pressure in the right side of the heart in acute right ventricular infarction. Br Heart J 63:98–102PubMedCrossRef
77.
go back to reference Konstam MA, Cohen SR, Salem DN, Das D, Aronovitz MJ, Brockway BA (1986) Effect of amrinone on right ventricular function: predominance of afterload reduction. Circulation 74:359–366PubMedCrossRef Konstam MA, Cohen SR, Salem DN, Das D, Aronovitz MJ, Brockway BA (1986) Effect of amrinone on right ventricular function: predominance of afterload reduction. Circulation 74:359–366PubMedCrossRef
78.
go back to reference Grose R, Strain J, Yipintosoi T (1983) Right ventricular function in valvular heart disease: relation to pulmonary artery pressure. J Am Coll Cardiol 2:225–232PubMedCrossRef Grose R, Strain J, Yipintosoi T (1983) Right ventricular function in valvular heart disease: relation to pulmonary artery pressure. J Am Coll Cardiol 2:225–232PubMedCrossRef
79.
go back to reference Rouleau JL, Kapuku G, Pelletier S et al (2001) Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation 104:939–944PubMedCrossRef Rouleau JL, Kapuku G, Pelletier S et al (2001) Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation 104:939–944PubMedCrossRef
80.
go back to reference Bogaard HJ, Natarajan R, Henderson SC et al (2009) Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation 120:1951–1960PubMedCrossRef Bogaard HJ, Natarajan R, Henderson SC et al (2009) Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation 120:1951–1960PubMedCrossRef
81.
go back to reference Hardziyenka M, Campian ME, de Bruin-Bon HA, Michel MC, Tan HL (2006) Sequence of echocardiographic changes during development of right ventricular failure in rat. J Am Soc Echocardiogr 19:1272–1279PubMedCrossRef Hardziyenka M, Campian ME, de Bruin-Bon HA, Michel MC, Tan HL (2006) Sequence of echocardiographic changes during development of right ventricular failure in rat. J Am Soc Echocardiogr 19:1272–1279PubMedCrossRef
82.
go back to reference Hulsmann M, Stefenelli T, Berger R et al (2000) Response of right ventricular function to prostaglandin E1 infusion predicts outcome for severe chronic heart failure patients awaiting urgent transplantation. J Heart Lung Transplant 19:939–945PubMedCrossRef Hulsmann M, Stefenelli T, Berger R et al (2000) Response of right ventricular function to prostaglandin E1 infusion predicts outcome for severe chronic heart failure patients awaiting urgent transplantation. J Heart Lung Transplant 19:939–945PubMedCrossRef
83.
go back to reference Gavazzi A, Ghio S, Scelsi L et al (2003) Response of the right ventricle to acute pulmonary vasodilation predicts the outcome in patients with advanced heart failure and pulmonary hypertension. Am Heart J 145:310–316PubMedCrossRef Gavazzi A, Ghio S, Scelsi L et al (2003) Response of the right ventricle to acute pulmonary vasodilation predicts the outcome in patients with advanced heart failure and pulmonary hypertension. Am Heart J 145:310–316PubMedCrossRef
84.
go back to reference Frist WH, Lorenz CH, Walker ES et al (1995) MRI complements standard assessment of right ventricular function after lung transplantation. Ann Thorac Surg 60:268–271PubMedCrossRef Frist WH, Lorenz CH, Walker ES et al (1995) MRI complements standard assessment of right ventricular function after lung transplantation. Ann Thorac Surg 60:268–271PubMedCrossRef
85.
go back to reference Bleeker GB, Schalij MJ, Nihoyannopoulos P et al (2005) Left ventricular dyssynchrony predicts right ventricular remodeling after cardiac resynchronization therapy. J Am Coll Cardiol 46:2264–2269PubMedCrossRef Bleeker GB, Schalij MJ, Nihoyannopoulos P et al (2005) Left ventricular dyssynchrony predicts right ventricular remodeling after cardiac resynchronization therapy. J Am Coll Cardiol 46:2264–2269PubMedCrossRef
86.
go back to reference D’Andrea A, Salerno G, Scarafile R et al (2009) Right ventricular myocardial function in patients with either idiopathic or ischemic dilated cardiomyopathy without clinical sign of right heart failure: effects of cardiac resynchronization therapy. Pacing Clin Electrophysiol 32:1017–1029PubMedCrossRef D’Andrea A, Salerno G, Scarafile R et al (2009) Right ventricular myocardial function in patients with either idiopathic or ischemic dilated cardiomyopathy without clinical sign of right heart failure: effects of cardiac resynchronization therapy. Pacing Clin Electrophysiol 32:1017–1029PubMedCrossRef
87.
go back to reference Rajagopalan N, Suffoletto MS, Tanabe M et al (2007) Right ventricular function following cardiac resynchronization therapy. Am J Cardiol 100:1434–1436PubMedCrossRef Rajagopalan N, Suffoletto MS, Tanabe M et al (2007) Right ventricular function following cardiac resynchronization therapy. Am J Cardiol 100:1434–1436PubMedCrossRef
88.
go back to reference Pfisterer ME, Battler A, Zaret BL (1985) Range of normal values for left and right ventricular ejection fraction at rest and during exercise assessed by radionuclide angiocardiography. Eur Heart J 6:647–655PubMed Pfisterer ME, Battler A, Zaret BL (1985) Range of normal values for left and right ventricular ejection fraction at rest and during exercise assessed by radionuclide angiocardiography. Eur Heart J 6:647–655PubMed
89.
go back to reference Brieke A, DeNofrio D (2005) Right ventricular dysfunction in chronic dilated cardiomyopathy and heart failure. Coron Artery Dis 16:5–11PubMedCrossRef Brieke A, DeNofrio D (2005) Right ventricular dysfunction in chronic dilated cardiomyopathy and heart failure. Coron Artery Dis 16:5–11PubMedCrossRef
90.
go back to reference Henein MY, O’Sullivan CA, Coats AJ, Gibson DG (1998) Angiotensin-converting enzyme (ACE) inhibitors revert abnormal right ventricular filling in patients with restrictive left ventricular disease. J Am Coll Cardiol 32:1187–1193PubMedCrossRef Henein MY, O’Sullivan CA, Coats AJ, Gibson DG (1998) Angiotensin-converting enzyme (ACE) inhibitors revert abnormal right ventricular filling in patients with restrictive left ventricular disease. J Am Coll Cardiol 32:1187–1193PubMedCrossRef
91.
go back to reference Quaife RA, Christian PE, Gilbert EM, Datz FL, Volkman K, Bristow MR (1998) Effects of carvedilol on right ventricular function in chronic heart failure. Am J Cardiol 81:247–250PubMedCrossRef Quaife RA, Christian PE, Gilbert EM, Datz FL, Volkman K, Bristow MR (1998) Effects of carvedilol on right ventricular function in chronic heart failure. Am J Cardiol 81:247–250PubMedCrossRef
92.
go back to reference Tatli E, Kurum T, Aktoz M, Buyuklu M (2008) Effects of carvedilol on right ventricular ejection fraction and cytokines levels in patients with systolic heart failure. Int J Cardiol 125:273–276PubMedCrossRef Tatli E, Kurum T, Aktoz M, Buyuklu M (2008) Effects of carvedilol on right ventricular ejection fraction and cytokines levels in patients with systolic heart failure. Int J Cardiol 125:273–276PubMedCrossRef
93.
go back to reference Beck-da-Silva L, de Bold A, Davies R et al (2004) Effect of bisoprolol on right ventricular function and brain natriuretic peptide in patients with heart failure. Congest Heart Fail 10:127–132PubMedCrossRef Beck-da-Silva L, de Bold A, Davies R et al (2004) Effect of bisoprolol on right ventricular function and brain natriuretic peptide in patients with heart failure. Congest Heart Fail 10:127–132PubMedCrossRef
94.
go back to reference Verhaert D, Mullens W, Borowski AG et al. (2010) Right ventricular response to intensive medical therapy in advanced decompensated heart failure. Circ Heart Fail 3(3):340–346 Verhaert D, Mullens W, Borowski AG et al. (2010) Right ventricular response to intensive medical therapy in advanced decompensated heart failure. Circ Heart Fail 3(3):340–346
95.
go back to reference Sharp RP, Gregory A, Mowdy MH, Sirajuddin R (2004) Nesiritide for treatment of heart failure due to right ventricular dysfunction. Pharmacotherapy 24:1236–1240PubMedCrossRef Sharp RP, Gregory A, Mowdy MH, Sirajuddin R (2004) Nesiritide for treatment of heart failure due to right ventricular dysfunction. Pharmacotherapy 24:1236–1240PubMedCrossRef
96.
go back to reference Yahagi N, Kumon K, Nakatani T et al (1995) Inhaled nitric oxide for the management of acute right ventricular failure in patients with a left ventricular assist system. Artif Organs 19:557–558PubMedCrossRef Yahagi N, Kumon K, Nakatani T et al (1995) Inhaled nitric oxide for the management of acute right ventricular failure in patients with a left ventricular assist system. Artif Organs 19:557–558PubMedCrossRef
97.
go back to reference Mertes PM, Pinelli G, Hubert T et al (1995) Impact of nitric oxide inhalation on right ventricular failure after implantation of Novacor left ventricular assist system. J Thorac Cardiovasc Surg 109:1251PubMedCrossRef Mertes PM, Pinelli G, Hubert T et al (1995) Impact of nitric oxide inhalation on right ventricular failure after implantation of Novacor left ventricular assist system. J Thorac Cardiovasc Surg 109:1251PubMedCrossRef
98.
go back to reference Fujita Y, Nishida O, Sobue K et al (2002) Nitric oxide inhalation is useful in the management of right ventricular failure caused by myocardial infarction. Crit Care Med 30:1379–1381PubMedCrossRef Fujita Y, Nishida O, Sobue K et al (2002) Nitric oxide inhalation is useful in the management of right ventricular failure caused by myocardial infarction. Crit Care Med 30:1379–1381PubMedCrossRef
99.
go back to reference Wasson S, Govindarajan G, Reddy HK, Flaker G (2004) The role of nitric oxide and vasopressin in refractory right heart failure. J Cardiovasc Pharmacol Ther 9:9–11PubMedCrossRef Wasson S, Govindarajan G, Reddy HK, Flaker G (2004) The role of nitric oxide and vasopressin in refractory right heart failure. J Cardiovasc Pharmacol Ther 9:9–11PubMedCrossRef
100.
go back to reference Inglessis I, Shin JT, Lepore JJ et al (2004) Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. J Am Coll Cardiol 44:793–798PubMedCrossRef Inglessis I, Shin JT, Lepore JJ et al (2004) Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. J Am Coll Cardiol 44:793–798PubMedCrossRef
101.
go back to reference Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD (2007) Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol 50:2136–2144PubMedCrossRef Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD (2007) Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol 50:2136–2144PubMedCrossRef
102.
go back to reference Lewis GD, Lachmann J, Camuso J et al (2007) Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation 115:59–66PubMedCrossRef Lewis GD, Lachmann J, Camuso J et al (2007) Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation 115:59–66PubMedCrossRef
103.
go back to reference Nagendran J, Archer SL, Soliman D et al (2007) Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation 116:238–248PubMedCrossRef Nagendran J, Archer SL, Soliman D et al (2007) Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation 116:238–248PubMedCrossRef
104.
go back to reference Poelzl G, Zwick RH, Grander W et al (2008) Safety and effectiveness of levosimendan in patients with predominant right heart failure. Herz 33:368–373PubMedCrossRef Poelzl G, Zwick RH, Grander W et al (2008) Safety and effectiveness of levosimendan in patients with predominant right heart failure. Herz 33:368–373PubMedCrossRef
105.
go back to reference Yilmaz MB, Yontar C, Erdem A et al (2009) Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels 24:16–21PubMedCrossRef Yilmaz MB, Yontar C, Erdem A et al (2009) Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels 24:16–21PubMedCrossRef
106.
go back to reference Pagnamenta A, Fesler P, Vandinivit A, Brimioulle S, Naeije R (2003) Pulmonary vascular effects of dobutamine in experimental pulmonary hypertension. Crit Care Med 31:1140–1146PubMedCrossRef Pagnamenta A, Fesler P, Vandinivit A, Brimioulle S, Naeije R (2003) Pulmonary vascular effects of dobutamine in experimental pulmonary hypertension. Crit Care Med 31:1140–1146PubMedCrossRef
107.
go back to reference Kaul TK, Fields BL (2000) Postoperative acute refractory right ventricular failure: incidence, pathogenesis, management and prognosis. Cardiovasc Surg 8:1–9PubMedCrossRef Kaul TK, Fields BL (2000) Postoperative acute refractory right ventricular failure: incidence, pathogenesis, management and prognosis. Cardiovasc Surg 8:1–9PubMedCrossRef
108.
go back to reference Kendall SW, Bittner HB, Peterseim DS, Campbell KA, Van Trigt P (1997) Right ventricular function in the donor heart. Eur J Cardiothorac Surg 11:609–615PubMedCrossRef Kendall SW, Bittner HB, Peterseim DS, Campbell KA, Van Trigt P (1997) Right ventricular function in the donor heart. Eur J Cardiothorac Surg 11:609–615PubMedCrossRef
109.
go back to reference Leeman M, Van Cutsem M, Vachiery JL, Antoine M, Leclerc JL (1996) Determinants of right ventricular failure after heart transplantation. Acta Cardiol 51:441–449PubMed Leeman M, Van Cutsem M, Vachiery JL, Antoine M, Leclerc JL (1996) Determinants of right ventricular failure after heart transplantation. Acta Cardiol 51:441–449PubMed
110.
go back to reference Kihara S, Kawai A, Fukuda T et al (2002) Effects of milrinone for right ventricular failure after left ventricular assist device implantation. Heart Vessels 16:69–71PubMedCrossRef Kihara S, Kawai A, Fukuda T et al (2002) Effects of milrinone for right ventricular failure after left ventricular assist device implantation. Heart Vessels 16:69–71PubMedCrossRef
111.
go back to reference Wagner F, Dandel M, Gunther G et al. (1997) Nitric oxide inhalation in the treatment of right ventricular dysfunction following left ventricular assist device implantation. Circulation 96:II-291-6 Wagner F, Dandel M, Gunther G et al. (1997) Nitric oxide inhalation in the treatment of right ventricular dysfunction following left ventricular assist device implantation. Circulation 96:II-291-6
112.
go back to reference Bhorade S, Christenson J, O’Connor M, Lavoie A, Pohlman A, Hall JB (1999) Response to inhaled nitric oxide in patients with acute right heart syndrome. Am J Respir Crit Care Med 159:571–579PubMed Bhorade S, Christenson J, O’Connor M, Lavoie A, Pohlman A, Hall JB (1999) Response to inhaled nitric oxide in patients with acute right heart syndrome. Am J Respir Crit Care Med 159:571–579PubMed
113.
go back to reference Darrah WC, Sharpe MD, Guiraudon GM, Neal A (1997) Intraaortic balloon counterpulsation improves right ventricular failure resulting from pressure overload. Ann Thorac Surg 64:1718–1723, discussion 23–24 Darrah WC, Sharpe MD, Guiraudon GM, Neal A (1997) Intraaortic balloon counterpulsation improves right ventricular failure resulting from pressure overload. Ann Thorac Surg 64:1718–1723, discussion 23–24
114.
go back to reference Arafa OE, Geiran OR, Andersen K, Fosse E, Simonsen S, Svennevig JL (2000) Intraaortic balloon pumping for predominantly right ventricular failure after heart transplantation. Ann Thorac Surg 70:1587–1593PubMedCrossRef Arafa OE, Geiran OR, Andersen K, Fosse E, Simonsen S, Svennevig JL (2000) Intraaortic balloon pumping for predominantly right ventricular failure after heart transplantation. Ann Thorac Surg 70:1587–1593PubMedCrossRef
115.
go back to reference Boeken U, Feindt P, Litmathe J, Kurt M, Gams E (2009) Intraaortic balloon pumping in patients with right ventricular insufficiency after cardiac surgery: parameters to predict failure of IABP Support. Thorac Cardiovasc Surg 57:324–328PubMedCrossRef Boeken U, Feindt P, Litmathe J, Kurt M, Gams E (2009) Intraaortic balloon pumping in patients with right ventricular insufficiency after cardiac surgery: parameters to predict failure of IABP Support. Thorac Cardiovasc Surg 57:324–328PubMedCrossRef
116.
go back to reference Nordhaug D, Steensrud T, Muller S, Husnes KV, Myrmel T (2004) Intraaortic balloon pumping improves hemodynamics and right ventricular efficiency in acute ischemic right ventricular failure. Ann Thorac Surg 78:1426–1432PubMedCrossRef Nordhaug D, Steensrud T, Muller S, Husnes KV, Myrmel T (2004) Intraaortic balloon pumping improves hemodynamics and right ventricular efficiency in acute ischemic right ventricular failure. Ann Thorac Surg 78:1426–1432PubMedCrossRef
117.
go back to reference Klotz S, Naka Y, Oz MC, Burkhoff D (2005) Biventricular assist device-induced right ventricular reverse structural and functional remodeling. J Heart Lung Transplant 24:1195–1201PubMedCrossRef Klotz S, Naka Y, Oz MC, Burkhoff D (2005) Biventricular assist device-induced right ventricular reverse structural and functional remodeling. J Heart Lung Transplant 24:1195–1201PubMedCrossRef
118.
go back to reference Frazier OH, Rose EA, Macmanus Q et al (1992) Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. Ann Thorac Surg 53:1080–1090PubMedCrossRef Frazier OH, Rose EA, Macmanus Q et al (1992) Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. Ann Thorac Surg 53:1080–1090PubMedCrossRef
119.
go back to reference Nakatani S, Thomas JD, Savage RM, Vargo RL, Smedira NG, McCarthy PM (1996) Prediction of right ventricular dysfunction after left ventricular assist device implantation. Circulation 94:II216–II221 Nakatani S, Thomas JD, Savage RM, Vargo RL, Smedira NG, McCarthy PM (1996) Prediction of right ventricular dysfunction after left ventricular assist device implantation. Circulation 94:II216–II221
120.
go back to reference Lee S, Kamdar F, Madlon-Kay R et al. (2010) Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function. J Heart Lung Transplant 29:209–215 Lee S, Kamdar F, Madlon-Kay R et al. (2010) Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function. J Heart Lung Transplant 29:209–215
121.
go back to reference Lam KM, Ennis S, O’Driscoll G, Solis JM, Macgillivray T, Picard MH (2009) Observations from non-invasive measures of right heart hemodynamics in left ventricular assist device patients. J Am Soc Echocardiogr 22:1055–1062PubMedCrossRef Lam KM, Ennis S, O’Driscoll G, Solis JM, Macgillivray T, Picard MH (2009) Observations from non-invasive measures of right heart hemodynamics in left ventricular assist device patients. J Am Soc Echocardiogr 22:1055–1062PubMedCrossRef
122.
go back to reference Maeder MT, Leet A, Ross A, Esmore D, Kaye DM (2009) Changes in right ventricular function during continuous-low left ventricular assist device support. J Heart Lung Transplant 28:360–366PubMedCrossRef Maeder MT, Leet A, Ross A, Esmore D, Kaye DM (2009) Changes in right ventricular function during continuous-low left ventricular assist device support. J Heart Lung Transplant 28:360–366PubMedCrossRef
123.
go back to reference Palardy M, Nohria A, Rivero J et al. (2010) Right ventricular dysfunction during intensive pharmacologic unloading persists after mechanical unloading. J Card Fail 16:218–224 Palardy M, Nohria A, Rivero J et al. (2010) Right ventricular dysfunction during intensive pharmacologic unloading persists after mechanical unloading. J Card Fail 16:218–224
124.
go back to reference Oz MC, Argenziano M, Catanese KA et al (1997) Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation? Circulation 95:1844–1852PubMed Oz MC, Argenziano M, Catanese KA et al (1997) Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation? Circulation 95:1844–1852PubMed
125.
go back to reference Kormos RL, Teuteberg JJ, Pagani FD et al. (2010) Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg 139:1316–1324 Kormos RL, Teuteberg JJ, Pagani FD et al. (2010) Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg 139:1316–1324
126.
go back to reference Drakos SG, Janicki L, Horne BD et al. (2010) Risk factors predictive of right ventricular failure after left ventricular assist device implantation. Am J Cardiol 105:1030–1035 Drakos SG, Janicki L, Horne BD et al. (2010) Risk factors predictive of right ventricular failure after left ventricular assist device implantation. Am J Cardiol 105:1030–1035
127.
go back to reference Mandarino WA, Winowich S, Gorcsan J III et al (1997) Right ventricular performance and left ventricular assist device filling. Ann Thorac Surg 63:1044–1049PubMedCrossRef Mandarino WA, Winowich S, Gorcsan J III et al (1997) Right ventricular performance and left ventricular assist device filling. Ann Thorac Surg 63:1044–1049PubMedCrossRef
128.
go back to reference Patel ND, Weiss ES, Schaffer J et al. (2008) Right heart dysfunction after left ventricular assist device implantation: a comparison of the pulsatile HeartMate I and axial-flow HeartMate II devices. Ann Thorac Surg 86:832–840, discussion -40 Patel ND, Weiss ES, Schaffer J et al. (2008) Right heart dysfunction after left ventricular assist device implantation: a comparison of the pulsatile HeartMate I and axial-flow HeartMate II devices. Ann Thorac Surg 86:832–840, discussion -40
129.
go back to reference Dang NC, Topkara VK, Mercando M et al (2006) Right heart failure after left ventricular assist device implantation in patients with chronic congestive heart failure. J Heart Lung Transplant 25:1–6PubMedCrossRef Dang NC, Topkara VK, Mercando M et al (2006) Right heart failure after left ventricular assist device implantation in patients with chronic congestive heart failure. J Heart Lung Transplant 25:1–6PubMedCrossRef
130.
go back to reference Kavarana MN, Pessin-Minsley MS, Urtecho J et al (2002) Right ventricular dysfunction and organ failure in left ventricular assist device recipients: a continuing problem. Ann Thorac Surg 73:745–750PubMedCrossRef Kavarana MN, Pessin-Minsley MS, Urtecho J et al (2002) Right ventricular dysfunction and organ failure in left ventricular assist device recipients: a continuing problem. Ann Thorac Surg 73:745–750PubMedCrossRef
131.
go back to reference Fukamachi K, McCarthy PM, Smedira NG, Vargo RL, Starling RC, Young JB (1999) Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion. Ann Thorac Surg 68:2181–2184PubMedCrossRef Fukamachi K, McCarthy PM, Smedira NG, Vargo RL, Starling RC, Young JB (1999) Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion. Ann Thorac Surg 68:2181–2184PubMedCrossRef
132.
go back to reference Ochiai Y, McCarthy PM, Smedira NG et al (2002) Predictors of severe right ventricular failure after implantable left ventricular assist device insertion: analysis of 245 patients. Circulation 106:I198–I202PubMedCrossRef Ochiai Y, McCarthy PM, Smedira NG et al (2002) Predictors of severe right ventricular failure after implantable left ventricular assist device insertion: analysis of 245 patients. Circulation 106:I198–I202PubMedCrossRef
133.
go back to reference Matthews JC, Koelling TM, Pagani FD, Aaronson KD (2008) The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates. J Am Coll Cardiol 51:2163–2172PubMedCrossRef Matthews JC, Koelling TM, Pagani FD, Aaronson KD (2008) The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates. J Am Coll Cardiol 51:2163–2172PubMedCrossRef
134.
go back to reference Kormos RL, Teuteberg JJ, Pagani FD et al (2010) Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg 139:1316–1324PubMedCrossRef Kormos RL, Teuteberg JJ, Pagani FD et al (2010) Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg 139:1316–1324PubMedCrossRef
135.
go back to reference Santambrogio L, Bianchi T, Fuardo M et al (2006) Right ventricular failure after left ventricular assist device insertion: preoperative risk factors. Interact Cardiovasc Thorac Surg. 5:379–382PubMedCrossRef Santambrogio L, Bianchi T, Fuardo M et al (2006) Right ventricular failure after left ventricular assist device insertion: preoperative risk factors. Interact Cardiovasc Thorac Surg. 5:379–382PubMedCrossRef
136.
go back to reference Deswarte G, Kirsch M, Lesault PF, Trochu JN, Damy T (2010) Right ventricular reserve and outcome after continuous-flow left ventricular assist device implantation. J Heart Lung Transplant 29:1196–1198 Deswarte G, Kirsch M, Lesault PF, Trochu JN, Damy T (2010) Right ventricular reserve and outcome after continuous-flow left ventricular assist device implantation. J Heart Lung Transplant 29:1196–1198
137.
go back to reference Schmid C, Radovancevic B (2002) When should we consider right ventricular support? Thorac Cardiovasc Surg 50:204–207PubMedCrossRef Schmid C, Radovancevic B (2002) When should we consider right ventricular support? Thorac Cardiovasc Surg 50:204–207PubMedCrossRef
138.
go back to reference Argenziano M, Choudhri AF, Moazami N et al (1998) Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. Ann Thorac Surg 65:340–345PubMedCrossRef Argenziano M, Choudhri AF, Moazami N et al (1998) Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. Ann Thorac Surg 65:340–345PubMedCrossRef
139.
go back to reference Chang JC, Sawa Y, Ohtake S et al (1997) Hemodynamic effect of inhaled nitric oxide in dilated cardiomyopathy patients on LVAD support. ASAIO J 43:M418–M421PubMedCrossRef Chang JC, Sawa Y, Ohtake S et al (1997) Hemodynamic effect of inhaled nitric oxide in dilated cardiomyopathy patients on LVAD support. ASAIO J 43:M418–M421PubMedCrossRef
140.
go back to reference Atiemo AD, Conte JV, Heldman AW (2006) Resuscitation and recovery from acute right ventricular failure using a percutaneous right ventricular assist device. Catheter Cardiovasc Interv 68:78–82PubMedCrossRef Atiemo AD, Conte JV, Heldman AW (2006) Resuscitation and recovery from acute right ventricular failure using a percutaneous right ventricular assist device. Catheter Cardiovasc Interv 68:78–82PubMedCrossRef
141.
go back to reference Christiansen S, Dohmen G, Autschbach R (2006) Treatment of right heart failure with a new microaxial blood pump. Asian Cardiovasc Thorac Ann 14:418–421PubMed Christiansen S, Dohmen G, Autschbach R (2006) Treatment of right heart failure with a new microaxial blood pump. Asian Cardiovasc Thorac Ann 14:418–421PubMed
142.
go back to reference Osaki S, Edwards NM, Johnson MR, Kohmoto T (2008) A novel use of the implantable ventricular assist device for isolated right heart failure. Interact Cardiovasc Thorac Surg 7:651–653PubMedCrossRef Osaki S, Edwards NM, Johnson MR, Kohmoto T (2008) A novel use of the implantable ventricular assist device for isolated right heart failure. Interact Cardiovasc Thorac Surg 7:651–653PubMedCrossRef
143.
go back to reference Sugiki H, Nakashima K, Vermes E, Loisance D, Kirsch M (2009) Temporary right ventricular support with Impella Recover RD axial flow pump. Asian Cardiovasc Thorac Ann 17:395–400PubMed Sugiki H, Nakashima K, Vermes E, Loisance D, Kirsch M (2009) Temporary right ventricular support with Impella Recover RD axial flow pump. Asian Cardiovasc Thorac Ann 17:395–400PubMed
144.
go back to reference Ueti OM, Camargo EE, Ueti Ade A, de Lima-Filho EC, Nogueira EA (2002) Assessment of right ventricular function with Doppler echocardiographic indices derived from tricuspid annular motion: comparison with radionuclide angiography. Heart 88:244–248PubMedCrossRef Ueti OM, Camargo EE, Ueti Ade A, de Lima-Filho EC, Nogueira EA (2002) Assessment of right ventricular function with Doppler echocardiographic indices derived from tricuspid annular motion: comparison with radionuclide angiography. Heart 88:244–248PubMedCrossRef
145.
go back to reference Lang RM, Bierig M, Devereux RB et al (2005) Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18:1440–1463PubMedCrossRef Lang RM, Bierig M, Devereux RB et al (2005) Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18:1440–1463PubMedCrossRef
146.
go back to reference Nageh MF, Kopelen HA, Zoghbi WA, Quinones MA, Nagueh SF (1999) Estimation of mean right atrial pressure using tissue Doppler imaging. Am J Cardiol 84:1448-51, A8 Nageh MF, Kopelen HA, Zoghbi WA, Quinones MA, Nagueh SF (1999) Estimation of mean right atrial pressure using tissue Doppler imaging. Am J Cardiol 84:1448-51, A8
147.
go back to reference Kormos RL, Gasior TA, Kawai A et al. (1996) Transplant candidate’s clinical status rather than right ventricular function defines need for univentricular versus biventricular support. J Thorac Cardiovasc Surg 111:773–782, discussion 82–83 Kormos RL, Gasior TA, Kawai A et al. (1996) Transplant candidate’s clinical status rather than right ventricular function defines need for univentricular versus biventricular support. J Thorac Cardiovasc Surg 111:773–782, discussion 82–83
148.
go back to reference Fitzpatrick JR III, Frederick JR, Hsu VM et al (2008) Risk score derived from pre-operative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant 27:1286–1292PubMedCrossRef Fitzpatrick JR III, Frederick JR, Hsu VM et al (2008) Risk score derived from pre-operative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant 27:1286–1292PubMedCrossRef
Metadata
Title
Right side of heart failure
Authors
Maya Guglin
Sameer Verma
Publication date
01-05-2012
Publisher
Springer US
Published in
Heart Failure Reviews / Issue 3/2012
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-011-9272-0

Other articles of this Issue 3/2012

Heart Failure Reviews 3/2012 Go to the issue