Skip to main content
Top
Published in: Heart Failure Reviews 1/2009

01-03-2009

Treatment of depression in patients with congestive heart failure

Author: Peter A. Shapiro

Published in: Heart Failure Reviews | Issue 1/2009

Login to get access

Abstract

Heart failure is common, and depression is common in heart failure patients, adding substantially to the burden of the disease. There is some evidence for the safe and at least modestly effective use of psychotherapy and antidepressants to treat depression in heart failure patients. Cognitive behavioral psychotherapy and selective serotonin reuptake inhibitors are first line treatments. The efficacy of depression treatment in altering cardiac outcomes in heart failure patients has yet to be established.
Literature
1.
go back to reference Rosamond W, Flegal K, Friday G et al (2007) Heart disease and stroke statistics–2007 update: a report from the American heart association statistics committee and stroke statistics subcommittee. Circulation 115, e69–171PubMedCrossRef Rosamond W, Flegal K, Friday G et al (2007) Heart disease and stroke statistics–2007 update: a report from the American heart association statistics committee and stroke statistics subcommittee. Circulation 115, e69–171PubMedCrossRef
2.
go back to reference Koenig HG (1998) Depression in hospitalized older patients with congestive heart failure. Gen Hosp Psychiatry 20:29–43PubMedCrossRef Koenig HG (1998) Depression in hospitalized older patients with congestive heart failure. Gen Hosp Psychiatry 20:29–43PubMedCrossRef
3.
go back to reference Jiang W, Alexander J, Christopher E et al (2001) Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med 161:1849–1856PubMedCrossRef Jiang W, Alexander J, Christopher E et al (2001) Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med 161:1849–1856PubMedCrossRef
4.
go back to reference Rumsfeld JS, Havranek E, Masoudi FA et al (2003) Depressive symptoms are the strongest predictors of short-term declines in health status in patients with heart failure. J Am Coll Cardiol 42:1811–1817PubMedCrossRef Rumsfeld JS, Havranek E, Masoudi FA et al (2003) Depressive symptoms are the strongest predictors of short-term declines in health status in patients with heart failure. J Am Coll Cardiol 42:1811–1817PubMedCrossRef
5.
go back to reference Ruo B, Rumsfeld JS, Hlatky MA, Liu H, Browner WS, Whooley MA (2003) Depressive symptoms and health-related quality of life: the heart and soul study. JAMA 290(2):215–221 Ruo B, Rumsfeld JS, Hlatky MA, Liu H, Browner WS, Whooley MA (2003) Depressive symptoms and health-related quality of life: the heart and soul study. JAMA 290(2):215–221
6.
go back to reference Faris R, Purcell H, Henein MY, Coats AJS (2002) Clinical depression is common and significantly associated with reduced survival in patients with non-ischaemic heart failure. Eur J Heart Fail 4(4):541–551 Faris R, Purcell H, Henein MY, Coats AJS (2002) Clinical depression is common and significantly associated with reduced survival in patients with non-ischaemic heart failure. Eur J Heart Fail 4(4):541–551
7.
go back to reference Freedland KE, Carney RM, Davila-Roman VG, Rich MW, Skala JA, Jaffe AS. (1998) Major depression and survival in congestive heart failure. Psychosom Med 60:118 Freedland KE, Carney RM, Davila-Roman VG, Rich MW, Skala JA, Jaffe AS. (1998) Major depression and survival in congestive heart failure. Psychosom Med 60:118
8.
go back to reference Roose SP, Glassman AH (1989) Cardiovascular effects of tricyclic antidepressants in depressed patients with and without heart disease. J Clin Psychiatry 50:S1–18 Roose SP, Glassman AH (1989) Cardiovascular effects of tricyclic antidepressants in depressed patients with and without heart disease. J Clin Psychiatry 50:S1–18
9.
go back to reference Roose SP, Glassman AH, Dalack GW (1989) Depression, heart disease, and tricyclic antidepressants. J Clin Psychiatry 50:12–16PubMed Roose SP, Glassman AH, Dalack GW (1989) Depression, heart disease, and tricyclic antidepressants. J Clin Psychiatry 50:12–16PubMed
10.
go back to reference Roose SP, Glassman AH, Giardina EGV et al (1986) Nortriptyline in depressed patients with left ventricular impairment. JAMA 256:3253–3257PubMedCrossRef Roose SP, Glassman AH, Giardina EGV et al (1986) Nortriptyline in depressed patients with left ventricular impairment. JAMA 256:3253–3257PubMedCrossRef
11.
go back to reference CAST Investigators (1989) Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 321:406–412CrossRef CAST Investigators (1989) Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 321:406–412CrossRef
12.
go back to reference Echt DS, Liebson PR, Mitchelle LB et al (1991) Mortality and morbidity in patients receiving encainide, flecainide or placebo. N Engl J Med 324:781–788PubMedCrossRef Echt DS, Liebson PR, Mitchelle LB et al (1991) Mortality and morbidity in patients receiving encainide, flecainide or placebo. N Engl J Med 324:781–788PubMedCrossRef
13.
go back to reference CAST II Investigators (1992) Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction. N Engl J Med 327:227–233 CAST II Investigators (1992) Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction. N Engl J Med 327:227–233
14.
go back to reference Morganroth J, Goin JE (1991) Quinidine-related mortality in the short-to-medium-term treatment of ventricular arrhythmias. Circulation 84:1977–1983PubMed Morganroth J, Goin JE (1991) Quinidine-related mortality in the short-to-medium-term treatment of ventricular arrhythmias. Circulation 84:1977–1983PubMed
15.
go back to reference Glassman AH, Roose SP, Bigger JT Jr (1993) The safety of tricyclic antidepressants in cardiac patients. Risk-benefit reconsidered. JAMA 269:2673–2675PubMedCrossRef Glassman AH, Roose SP, Bigger JT Jr (1993) The safety of tricyclic antidepressants in cardiac patients. Risk-benefit reconsidered. JAMA 269:2673–2675PubMedCrossRef
16.
go back to reference Sheline YI, Freedland KE, Carney RM (1997) How safe are serotonin reuptake inhibitors for depression in patients with coronary heart disease? Am J Med 102(1):54–59PubMedCrossRef Sheline YI, Freedland KE, Carney RM (1997) How safe are serotonin reuptake inhibitors for depression in patients with coronary heart disease? Am J Med 102(1):54–59PubMedCrossRef
17.
go back to reference Shapiro PA (2004) Heart disease. In: Levenson JL (ed) APPI textbook of psychosomatic medicine. APPI, Washington, D.C., pp 423–444 Shapiro PA (2004) Heart disease. In: Levenson JL (ed) APPI textbook of psychosomatic medicine. APPI, Washington, D.C., pp 423–444
18.
go back to reference Roose SP, Glassman AH, Attia E, Woodring S (1994) Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia. Am J Psychiatry 151:1735–1739PubMed Roose SP, Glassman AH, Attia E, Woodring S (1994) Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia. Am J Psychiatry 151:1735–1739PubMed
19.
go back to reference Roose SP, Glassman AH, Attia E, Woodring S, Giardina EGV, Bigger JT (1998) Cardiovascular effects of fluoxetine in depressed patients with heart disease. Am J Psychiatry 155:660–665PubMed Roose SP, Glassman AH, Attia E, Woodring S, Giardina EGV, Bigger JT (1998) Cardiovascular effects of fluoxetine in depressed patients with heart disease. Am J Psychiatry 155:660–665PubMed
20.
go back to reference Roose SP, Laghrissi-Thode F, Kennedy JS et al (1998) Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease. JAMA 279:287–291PubMedCrossRef Roose SP, Laghrissi-Thode F, Kennedy JS et al (1998) Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease. JAMA 279:287–291PubMedCrossRef
21.
go back to reference Strik JJMH, Honig A, Lousberg R et al (2000) Efficacy and safety of fluoxetine in the treatment of patients with major depression after first myocardial infarction: findings from a double-blind, placebo-controlled trial. Psychosom Med 62(6):783–789 Strik JJMH, Honig A, Lousberg R et al (2000) Efficacy and safety of fluoxetine in the treatment of patients with major depression after first myocardial infarction: findings from a double-blind, placebo-controlled trial. Psychosom Med 62(6):783–789
22.
go back to reference Glassman AH, O’Connor CM, Califf RM et al (2002) Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA 288:701–709PubMedCrossRef Glassman AH, O’Connor CM, Califf RM et al (2002) Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA 288:701–709PubMedCrossRef
23.
go back to reference Glassman AH, Bigger JT, Gaffney M, Shapiro PA, Swenson JR. (2006) Onset of major depression associated with acute coronary syndromes. Relationship of onset, major depressive disorder history, and episode severity to sertraline benefit. Arch Gen Psychiatry 63:283–288PubMedCrossRef Glassman AH, Bigger JT, Gaffney M, Shapiro PA, Swenson JR. (2006) Onset of major depression associated with acute coronary syndromes. Relationship of onset, major depressive disorder history, and episode severity to sertraline benefit. Arch Gen Psychiatry 63:283–288PubMedCrossRef
24.
go back to reference Lesperance F, Frasure-Smith N, Koszycki D et al (2007) Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian cardiac randomized evaluation of antidepressant and psychotherapy efficacy (CREATE) trial. JAMA 297(4):367–379 Lesperance F, Frasure-Smith N, Koszycki D et al (2007) Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian cardiac randomized evaluation of antidepressant and psychotherapy efficacy (CREATE) trial. JAMA 297(4):367–379
25.
go back to reference Musselman DL, Tomer A, Manatunga AK et al (1996) Exaggerated platelet reactivity in major depression. Am J Psychiatry 153:1313–1317PubMed Musselman DL, Tomer A, Manatunga AK et al (1996) Exaggerated platelet reactivity in major depression. Am J Psychiatry 153:1313–1317PubMed
26.
go back to reference Laghrissi-Thode F, Wagner WR, Pollack BG, Johnson PC, Finkel MS. (1997) Elevated platelet factor 4 and beta-thromboglogulin plasma levels in depressed patients with ischemic heart disease. Biol Psychiatry 42:290–295PubMedCrossRef Laghrissi-Thode F, Wagner WR, Pollack BG, Johnson PC, Finkel MS. (1997) Elevated platelet factor 4 and beta-thromboglogulin plasma levels in depressed patients with ischemic heart disease. Biol Psychiatry 42:290–295PubMedCrossRef
27.
go back to reference Pollock BG, Laghrissi-Thode F, Wagner WR (2000) Evaluation of platelet activation in depressed patients with ischemic heart disease after paroxetine or nortriptyline treatment. J Clin Psychopharmacol 20(2):137–140PubMedCrossRef Pollock BG, Laghrissi-Thode F, Wagner WR (2000) Evaluation of platelet activation in depressed patients with ischemic heart disease after paroxetine or nortriptyline treatment. J Clin Psychopharmacol 20(2):137–140PubMedCrossRef
28.
go back to reference Serebruany VL, Glassman AH, Malinin AI et al (2003) Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Eur J Heart Fail 5:517–521PubMedCrossRef Serebruany VL, Glassman AH, Malinin AI et al (2003) Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Eur J Heart Fail 5:517–521PubMedCrossRef
29.
go back to reference Serebruany VL, Glassman AH, Malinin AI et al (2003) Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the sertraline antidepressant heart attack randomized trial (SADHART) platelet substudy. Circulation 108(8):939–944 Serebruany VL, Glassman AH, Malinin AI et al (2003) Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the sertraline antidepressant heart attack randomized trial (SADHART) platelet substudy. Circulation 108(8):939–944
31.
go back to reference Lesperance F, Frasure-Smith N, Laliberte MA et al (2003) An open-label study of nefazodone treatment of major depression in patients with congestive heart failure. Can J Psychiatry 48:695–701PubMed Lesperance F, Frasure-Smith N, Laliberte MA et al (2003) An open-label study of nefazodone treatment of major depression in patients with congestive heart failure. Can J Psychiatry 48:695–701PubMed
32.
go back to reference Roose SP, Dalack GW, Glassman AH, Woodring S, Walsh BT, Giardina EGV (1991) Cardiovascular effects of bupropion in depressed patients with heart disease. Am J Psychiatry 148:512–516PubMed Roose SP, Dalack GW, Glassman AH, Woodring S, Walsh BT, Giardina EGV (1991) Cardiovascular effects of bupropion in depressed patients with heart disease. Am J Psychiatry 148:512–516PubMed
33.
go back to reference Qin F, Shite J, Mao W, Liang C-S (2003) Selegiline attenuates cardiac oxidative stress and apoptosis in heart failure: association with improvement of cardiac function. Eur J Pharmacol 461(2–3):149–158PubMedCrossRef Qin F, Shite J, Mao W, Liang C-S (2003) Selegiline attenuates cardiac oxidative stress and apoptosis in heart failure: association with improvement of cardiac function. Eur J Pharmacol 461(2–3):149–158PubMedCrossRef
35.
go back to reference Wilens TE, Hammerness PG, Biederman J et al (2005) Blood pressure changes associated with medication treatment of adults with attention-deficit/hyperactivity disorder. J Clin Psychiatry 66(2):253–259PubMedCrossRef Wilens TE, Hammerness PG, Biederman J et al (2005) Blood pressure changes associated with medication treatment of adults with attention-deficit/hyperactivity disorder. J Clin Psychiatry 66(2):253–259PubMedCrossRef
36.
go back to reference Lavretsky H, Park S, Siddarth P, Kumar A, Reynolds CF III (2006) Methylphenidate-enhanced antidepressant response to citalopram in the elderly: a double-blind, placebo-controlled pilot trial. Am J Geriat Psychiatry 14(2):181–185 Lavretsky H, Park S, Siddarth P, Kumar A, Reynolds CF III (2006) Methylphenidate-enhanced antidepressant response to citalopram in the elderly: a double-blind, placebo-controlled pilot trial. Am J Geriat Psychiatry 14(2):181–185
37.
go back to reference Writing Committee for the ENRICHD Investigators (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial. JAMA 289(23):3106–3116 Writing Committee for the ENRICHD Investigators (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial. JAMA 289(23):3106–3116
38.
go back to reference Klerman GL, Weissman MM, Rounsaville BJ, Chevron ES (1984) Interpersonal psychotherapy of depression. Basic Books, New York Klerman GL, Weissman MM, Rounsaville BJ, Chevron ES (1984) Interpersonal psychotherapy of depression. Basic Books, New York
40.
go back to reference Zielinski RJ, Roose SP, Devanand DP, Woodring S, Sackeim H (1993) Cardiovascular complications of ECT in depressed patients with cardiac disease. Am J Psychiatry 150:904–909PubMed Zielinski RJ, Roose SP, Devanand DP, Woodring S, Sackeim H (1993) Cardiovascular complications of ECT in depressed patients with cardiac disease. Am J Psychiatry 150:904–909PubMed
41.
go back to reference Magid M, Lapid MI, Sampson SM, Mueller PS (2005) Use of electroconvulsive therapy in a patient 10 days after myocardial infarction. J ECT 21(3):182–185PubMedCrossRef Magid M, Lapid MI, Sampson SM, Mueller PS (2005) Use of electroconvulsive therapy in a patient 10 days after myocardial infarction. J ECT 21(3):182–185PubMedCrossRef
42.
go back to reference Nuttall GA, Bowersox MR, Douglass SB et al (2004) Morbidity and mortality in the use of electroconvulsive therapy. J ECT 20(4):237–241PubMedCrossRef Nuttall GA, Bowersox MR, Douglass SB et al (2004) Morbidity and mortality in the use of electroconvulsive therapy. J ECT 20(4):237–241PubMedCrossRef
43.
go back to reference Dolenc TJ, Barnes RD, Hayes DL, Rasmussen KG (2004) Electroconvulsive therapy in patients with cardiac pacemakers and implantable cardioverter defibrillators. Pacing Clin Electrophysiol 27(9):1257–1263PubMedCrossRef Dolenc TJ, Barnes RD, Hayes DL, Rasmussen KG (2004) Electroconvulsive therapy in patients with cardiac pacemakers and implantable cardioverter defibrillators. Pacing Clin Electrophysiol 27(9):1257–1263PubMedCrossRef
44.
go back to reference Rayburn BK. (1997) Electroconvulsive therapy in patients with heart failure or valvular heart disease. Convuls Ther 13(3):145–156PubMed Rayburn BK. (1997) Electroconvulsive therapy in patients with heart failure or valvular heart disease. Convuls Ther 13(3):145–156PubMed
Metadata
Title
Treatment of depression in patients with congestive heart failure
Author
Peter A. Shapiro
Publication date
01-03-2009
Publisher
Springer US
Published in
Heart Failure Reviews / Issue 1/2009
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-007-9058-6

Other articles of this Issue 1/2009

Heart Failure Reviews 1/2009 Go to the issue