Top

Documenta Ophthalmologica

Published in:

01-12-2012 | Original Research Article

Cortical potentials after electrical intraneural stimulation of the optic nerve during orbital enucleation

Authors: Mitja Benedičič, Matej Beltram, Brigita Drnovšek Olup, Roman Bošnjak

Published in: Documenta Ophthalmologica | Issue 3/2012

Abstract

Background

The aim of this study was to present cortical potentials after electrical intraneural stimulation of the optic nerve during orbital enucleation due to malignant melanoma of the choroid or the ciliary body. These cortical potentials were related to cortical potentials after electrical epidural stimulation of the optic nerve, recorded during non-manipulative phases of neurosurgery for central skull base tumors.

Methods

Cortical potentials were recorded with surface occipital electrode (Oz) in six patients undergoing orbital enucleation under total intravenous anesthesia. Two thin needle stimulating electrodes were inserted inside the intraorbital part of the optic nerve. The electrical stimulus consisted of a rectangular current pulse of varying intensity (0.2–10.0 mA) and duration (0.1–0.3 ms); the stimulation rate was 2 Hz; the bandpass filter was 1–1,000 Hz; the analysis time was 50–300 ms.

Results

Cortical potentials could not be obtained or were inconsistently elicitable in three patients with longstanding history (>3 months) of severe visual deterioration, while they consisted of several positive and negative deflections in a patient with a short history of mild visual impairment. In two other patients, cortical potentials consisted of N20, P30 and N40 waves.

Discussion

Cortical potentials after electrical intraneural stimulation of the optic nerve could be recorded in patients with a short history of visual deterioration and without optic nerve atrophy and appear more heterogeneous than cortical potentials after electrical epidural stimulation of the optic nerve, recorded during non-manipulative phases of neurosurgery for central skull base tumors.

Cedzich C, Schramm J (1990) Monitoring of flash visual evoked potentials during neurosurgical operations. Int Anesthesiol Clin 28:165–169PubMedCrossRef

Cedzich C, Schramm J, Fahlbusch R (1987) Are flash-evoked visual potentials useful for intraoperative monitoring of visual pathway function? Neurosurgery 21:709–715PubMedCrossRef

Cedzich C, Schramm J, Mengedoht CF, Fahlbusch R (1988) Factors that limit the use of flash visual evoked potentials for surgical monitoring. Electroencephalogr Clin Neurophysiol 71:142–145PubMedCrossRef

Chacko AG, Babu KS, Chandy MJ (1996) Value of visual evoked potential monitoring during trans-sphenoidal pituitary surgery. Br J Neurosurg 10:275–278PubMedCrossRef

Costa e Silva I, Wang AD, Symon L (1985) The application of flash visual evoked potentials during operations on the anterior visual pathways. Neurol Res 7:11–16PubMed

Feinsod M, Madey JM, Susal AL (1975) A new photostimulator for continuous recording of the visual evoked potential. Electroencephalogr Clin Neurophysiol 38:641–642PubMedCrossRef

Feinsod M, Selhorst JB, Hoyt WF, Wilson CB (1976) Monitoring optic nerve function during craniotomy. J Neurosurg 44:29–31PubMedCrossRef

Harding GF, Bland JD, Smith VH (1990) Visual evoked potential monitoring of optic nerve function during surgery. J Neurol Neurosurg Psychiatry 53:890–895PubMedCrossRef

Herzon GD, Zealear DL (1994) Intraoperative monitoring of the visual evoked potential during endoscopic sinus surgery. Otolaryngol Head Neck Surg 111:575–579PubMedCrossRef

10.

Raudzens PA (1982) Intraoperative monitoring of evoked potentials. Ann N Y Acad Sci 388:308–326PubMedCrossRef

11.

Kodama K, Goto T, Sato A, Sakai K, Tanaka Y, Hongo K (2010) Standard and limitation of intraoperative monitoring of the visual evoked potential. Acta Neurochir 152:643–648CrossRef

12.

Ota T, Kawai K, Kamada K, Kin T, Saito N (2010) Intraoperative monitoring of cortically recorded visual response for posterior visual pathway. J Neurosurg 112:285–294PubMedCrossRef

13.

Sasaki T, Itakura T, Suzuki K, Kasuya H, Munakata R, Muramatsu H, Ichikawa T, Sato T, Endo Y, Sakuma J, Matsumoto M (2010) Intraoperative monitoring of visual evoked potential: introduction of a clinically useful method. J Neurosurg 112:273–284PubMedCrossRef

14.

Kondo S, Kobayashi A, Nagata H, Kudo Y, Chiba Y (1998) Short-latency VEPs recorded directly from the optic nerve during microneurosurgery. 6th International Evoked Potentials Symposium

15.

Møller AR, Burgess JE, Sekhar LN (1987) Recording compound action potentials from the optic nerve in man and monkeys. Electroencephalogr Clin Neurophysiol 67:549–555PubMedCrossRef

16.

Kikuchi Y, Sasaki T, Matsumoto M, Oikawa T, Itakura T, Kodama N (2005) Optic nerve evoked potentials elicited by electrical stimulation. Neurol Med Chir 45:349–355 (Discussion 354-345)CrossRef

17.

Benedičič M, Bošnjak R (2011) Optic nerve potentials and cortical potentials after stimulation of the anterior visual pathway during neurosurgery. Doc Ophthalmol 122:115–125PubMedCrossRef

18.

Bošnjak R, Benedičič M (2008) Direct epidural electrical stimulation of the optic nerve: a new method for intraoperative assessment of function. J Neurosurg 109:647–653PubMedCrossRef

19.

Benedičič M, Bošnjak R (2011) Intraoperative monitoring of the visual function using cortical potentials after electrical epidural stimulation of the optic nerve. Acta Neurochir 153:1919–1927CrossRef

20.

Oozeer M, Veraart C, Legat V, Delbeke J (2005) Simulation of intra-orbital optic nerve electrical stimulation. Med Biol Eng Comput 43:608–617PubMedCrossRef

21.

Clifford-Jones RE, Landon DN, McDonald WI (1980) Remyelination during optic nerve compression. J Neurol Sci 46:239–243PubMedCrossRef

22.

Clifford-Jones RE, McDonald WI, Landon DN (1985) Chronic optic nerve compression. An experimental study. Brain 108(Pt 1):241–262PubMedCrossRef

23.

Jakobsson KE, Petruson B, Lindblom B (2002) Dynamics of visual improvement following chiasmal decompression. Quantitative pre- and postoperative observations. Acta Ophthalmol Scand 80:512–516PubMedCrossRef

24.

Anik I, Anik Y, Koc K, Ceylan S, Genc H, Altintas O, Ozdamar D, Baykal Ceylan D (2010) Evaluation of early visual recovery in pituitary macroadenomas after endoscopic endonasal transsphenoidal surgery: quantitative assessment with diffusion tensor imaging (DTI). Acta Neurochir 153:831–842CrossRef

25.

Cottee LJ, Daniel C, Loh WS, Harrison BM, Burke W (2003) Remyelination and recovery of conduction in cat optic nerve after demyelination by pressure. Exp Neurol 184:865–877PubMedCrossRef

Title: Cortical potentials after electrical intraneural stimulation of the optic nerve during orbital enucleation
Authors: Mitja Benedičič
Matej Beltram
Brigita Drnovšek Olup
Roman Bošnjak
Publication date: 01-12-2012
Publisher: Springer-Verlag
Published in: Documenta Ophthalmologica / Issue 3/2012
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI: https://doi.org/10.1007/s10633-012-9346-x

At a glance: The STEP trials

Springer Medicine

Cortical potentials after electrical intraneural stimulation of the optic nerve during orbital enucleation

Abstract

Background

Methods

Results

Discussion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Discussion

Please log in to get access to this content

Other articles of this Issue 3/2012

Inverse pattern of photoreceptor abnormalities in retinitis pigmentosa and cone–rod dystrophy

Response properties of slow PIII in the Large vls mutant

The effects of excitatory amino acids and their transporters on function and structure of the distal retina in albino rabbits

Assessment of macular function of glaucomatous eyes by multifocal electroretinograms

Motion and pattern cortical potentials in adults with high-functioning autism spectrum disorder

Establishing baseline rod electroretinogram values in achromatopsia and cone dystrophy