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01-10-2009 | Case Report

Dengue maculopathy: visual electrophysiology and optical coherence tomography

Authors: Thaís Sousa Mendes, Edmundo Frota de Almeida Sobrinho, Alexandre Antonio Marques Rosa, Laiza Medeiros dos Anjos, Genilma Matos da Costa, Givago da Silva Souza, Bruno Duarte Gomes, Cézar Akiyoshi Saito, Manoel da Silva Filho, Luiz Carlos de Lima Silveira

Published in: Documenta Ophthalmologica | Issue 2/2009

Abstract

The objective of this study was to evaluate the visual loss due to dengue fever using retinal and cortical electrophysiology and retinal imaging. The participants were three female patients with low visual acuity after dengue fever. They were evaluated by routine ophthalmological investigations, transient pattern electroretinogram (tPERG), transient pattern visual evoked cortical potential (tPVECP), and retinal optical coherence tomography (retinal OCT). tPERG and tPVECP amplitude (μV) and implicit time (ms) were the parameters evaluated using OCT retinal thickness (μm) and reflectivity. All patients presented low visual acuity and scotomata with or without changes in the oculus fundus. tPERG from two patients showed decreased amplitude or absence of the main components; it was not possible to record a reliable response in the third patient due to excessive blinking. tPVECP at 0.5 cpd was normal in all three patients, while at 2 cpd the main components were absent in one patient and normal in the other two patients. OCT image was abnormal in two patients, one of them with high reflectance areas and another with decreased retinal thickness (the third patient was not studied with this technique).The dengue fever can lead to visual impairment detectable by ophthalmological exams such as angiography, retinography, and OCT imaging, as well as retinal and cortical electrophysiology. Dengue maculopathy which could be caused by vascular alterations and/or aberrant immune response after infection may result in temporary or permanent visual losses.

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Title: Dengue maculopathy: visual electrophysiology and optical coherence tomography
Authors: Thaís Sousa Mendes
Edmundo Frota de Almeida Sobrinho
Alexandre Antonio Marques Rosa
Laiza Medeiros dos Anjos
Genilma Matos da Costa
Givago da Silva Souza
Bruno Duarte Gomes
Cézar Akiyoshi Saito
Manoel da Silva Filho
Luiz Carlos de Lima Silveira
Publication date: 01-10-2009
Publisher: Springer-Verlag
Published in: Documenta Ophthalmologica / Issue 2/2009
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI: https://doi.org/10.1007/s10633-009-9178-5

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Dengue maculopathy: visual electrophysiology and optical coherence tomography

Abstract

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Abstract

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