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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 7/2022

10-04-2022 | Metronidazole | Stanford Multidisciplinary Seminars

Stemming the Tide of Gastrointestinal Chronic Granulomatous Disease

Authors: Yasemin Cagil, Elizabeth Tong, Carolina Guimaraes, Joseph Andrews, Marwa Abu El Haija, George Triadafilopoulos, Ann Ming Yeh, Ami Shah

Published in: Digestive Diseases and Sciences | Issue 7/2022

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Excerpt

A 12-year-old male with chronic granulomatous disease (CGD) was evaluated at the pediatric gastroenterology clinic for diarrhea and bloody stools. He had been diagnosed with CGD in his infancy, when he was initially evaluated for a retroauricular suppurative granuloma. Growing up, he experienced several infections, including pulmonary histoplasmosis requiring prolonged course of antifungal therapy. …
Literature
1.
Ouahed J, Shouval D, Snapper S. Section 3L: GI Manifestations of Immunodeficiency. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. Second Ed. 2017. Page 135.
2.
3.
Khangura SK, Kamal N, Ho N et al. Gastrointestinal features of chronic granulomatous disease found during endoscopy. Clin Gastroenterol Hepatol. 2016;14:395-402.e5.CrossRef
4.
Schäppi MG, Smith VV, Goldblatt D et al. Colitis in chronic granulomatous disease. Arch Dis Child 2001;84:147–151.CrossRef
5.
6.
7.
Leiding J, Logan B, Yin Z et al. Resolution of CGD Related Colitis after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Granulomatous Disease: Early Results from the 6903 Study of the Primary Immune Deficiency Treatment Consortium (PIDTC). 2018. Abstract, Transplantation and Cellular Therapy. American Society for Transplantation and Cellular Therapy Volume 24, Issue 3, Supplement.
8.
Breton J, Kastl A., Hoffmann N et al. Efficacy of combination antibiotic therapy for refractory pediatric inflammatory bowel disease. Inflamm Bowel Dis 2019;25:1586–1593.CrossRef
9.
Sørensen CG, Karlsson WK, Amin FM, Lindelof M. Metronidazole-induced encephalopathy: a systematic review. J Neurol 2020;267:1–13.CrossRef
10.
Yazdani RM, Kayfan S, Cao J, Clarke RL, Pfeifer CM. MRI findings of metronidazole neurotoxicity in a pediatric patient with chronic diarrhea. Radiol Case Rep 2018;14:75–78.CrossRef
Metadata
Title
Stemming the Tide of Gastrointestinal Chronic Granulomatous Disease
Authors
Yasemin Cagil
Elizabeth Tong
Carolina Guimaraes
Joseph Andrews
Marwa Abu El Haija
George Triadafilopoulos
Ann Ming Yeh
Ami Shah
Publication date
10-04-2022
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 7/2022
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-022-07492-x

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