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Digestive Diseases and Sciences

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01-12-2021 | Barrett Esophagus | Correspondence

Microarray Analysis of the Chemoprophylaxis Effect of Zinc Gluconate: Inspiring but Caution Required

Authors: Yuqing Wang, Wei Liu, Xinxin Xu, Lei Yan

Published in: Digestive Diseases and Sciences | Issue 12/2021

Excerpt

Dear Editor, …

Valenzano MC, Rybakovsky E, Chen V et al. Zinc gluconate induces potentially cancer chemopreventive activity in Barrett’s esophagus: a phase 1 pilot study. Dig Dis Sci 2021;66:1195–1211. https://doi.org/10.1007/s10620-020-06319-x.CrossRefPubMed

Li Q, Li N, Lao Y, Lin W, Jiang G, Wei N, Wang C, Liu K, Wu J. Variable levels of long noncoding RNA expression in DNA mismatch repair-proficient early-stage colon cancer. Dig Dis Sci 2017;62:1235–1245. https://doi.org/10.1007/s10620-017-4465-6.CrossRefPubMed

Yuan B, Yang J, Gu H, Ma C. Down-regulation of LINC00460 represses metastasis of colorectal cancer via WWC2. Dig Dis Sci 2020;65:442–456. https://doi.org/10.1007/s10620-019-05801-5.CrossRefPubMed

Benjamini Y, Hochberg Y. Controlling the false discovery rate—a practical and powerful approach to multiple testing. J R Stat Soc Ser B Methodol 1995;57:289–300.

Assefa AT, De Paepe K, Everaert C, Mestdagh P, Thas O, Vandesompele J. Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data. Genome Biol 2018;19:96.CrossRef

Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 2015;43:e47.CrossRef

Valenzano MC, Mercado JM, Wang X, Zurbach EP, Raines J, McDonnell E, Morgan M, Farrell C, Rudolph D, Hwang A, Barr M, Cherian D, Bailey R, Raile B, Albert N, Thornton J, Zitin M, Abramson J, Newman G, Daum G, Mercogliano G, Mullin JM. Drug delivery of zinc to Barrett’s metaplasia by oral administration to Barrett’s esophagus patients. Ther Deliv 2014;5:257–264. https://doi.org/10.4155/tde.13.151.CrossRefPubMed

Fong LY, Taccioli C, Palamarchuk A, Tagliazucchi GM, Jing R, Smalley KJ, Fan S, Altemus J, Fiehn O, Huebner K, Farber JL, Croce CM. Abrogation of esophageal carcinoma development in miR-31 knockout rats. Proc Natl Acad Sci USA 2020;117:6075–6085. https://doi.org/10.1073/pnas.1920333117 (Epub 2020 Mar 2).CrossRefPubMedPubMedCentral

Taccioli C, Chen H, Jiang Y, Liu XP, Huang K, Smalley KJ, Farber JL, Croce CM, Fong LY. Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene 2012;31:4550–4558. https://doi.org/10.1038/onc.2011.592 (Epub 2011 Dec 19).CrossRefPubMed

Title: Microarray Analysis of the Chemoprophylaxis Effect of Zinc Gluconate: Inspiring but Caution Required
Authors: Yuqing Wang
Wei Liu
Xinxin Xu
Lei Yan
Publication date: 01-12-2021
Publisher: Springer US
Keyword: Barrett Esophagus
Published in: Digestive Diseases and Sciences / Issue 12/2021
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-021-07238-1

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