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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 2/2019

01-02-2019 | Multicenter Seminars: IBD (MUSE: IBD)

Raising the Barr: An Unexpected Lesion at Ileal–Cecal Resection

Authors: V. Mitsialis, Y. Wu, B. Gewurz, R. Bleday, L. A. Doyle, R. W. Winter, M. J. Hamilton

Published in: Digestive Diseases and Sciences | Issue 2/2019

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Excerpt

A 24-year-old man with stricturing, ileocolonic Crohn’s disease with recent partial small bowel obstruction (SBO) due to terminal ileal stenosis, was evaluated 1 day prior to previously scheduled elective ileocecal resection with complaints of fevers, myalgias, and fatigue. …
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Lopes S, Andrade P, Conde S, et al. Looking into enteric virome in patients with IBD: defining guilty or innocence? Inflamm Bowel Dis. 2017;23:1278–1284.CrossRefPubMed
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Shimada T, Nagata N, Okahara K, et al. PCR detection of human herpesviruses in colonic mucosa of individuals with inflammatory bowel disease: comparison with individuals with immunocompetency and HIV infection. PLoS ONE. 2017;12:e0184699.CrossRefPubMedPubMedCentral
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Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn’s disease: a meta-analysis. Clin Gastroenterol Hepatol. 2009;7:874–881.CrossRefPubMedPubMedCentral
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Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet. 2009;374:1617–1625.CrossRef
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Virdis F, Tacci S, Messina F, et al. Hemophagocytic lymphohistiocytosis caused by primary Epstein–Barr virus in patient with Crohn’s disease. World J Gastrointest Surg. 2013;5:306–308.CrossRefPubMedPubMedCentral
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Biank VF, Sheth MK, Talano J, et al. Association of Crohn’s disease, thiopurines, and primary Epstein–Barr virus infection with hemophagocytic lymphohistiocytosis. J Pediatr. 2011;159:808–812.CrossRefPubMedPubMedCentral
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Connors W, Griffiths C, Patel J, et al. Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. BMC Gastroenterol. 2014;14:127.CrossRefPubMedPubMedCentral
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Juan A, Lobatón T, Tapia G, et al. Epstein–Barr virus-positive mucocutaneous ulcer in Crohn’s disease. A condition to consider in immunosuppressed IBD patients. Dig Liver Dis. 2017;49:934–937.CrossRefPubMed
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Dojcinov SD, Venkataraman G, Raffeld M, et al. EBV positive mucocutaneous ulcer—a study of 26 cases associated with various sources of immunosuppression. Am J Surg Pathol. 2010;34:405–417.CrossRefPubMedPubMedCentral
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Roberts TK, Chen X, Liao JJ. Diagnostic and therapeutic challenges of EBV-positive mucocutaneous ulcer: a case report and systematic review of the literature. Exp Hematol Oncol. 2016;5:13.CrossRefPubMedPubMedCentral
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Matnani R, Peker D. Azathioprine induced Epstein Barr virus-positive mucocutaneous ulcer arising in perianal fistula and abscess associated with Crohn’s disease. J Crohns Colitis. 2014;8:1747–1748.CrossRefPubMed
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Moran NR, Webster B, Lee KM, et al. Epstein Barr virus-positive mucocutaneous ulcer of the colon associated Hodgkin lymphoma in Crohn’s disease. World J Gastroenterol. 2015;21:6072–6076.CrossRefPubMedPubMedCentral
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Hart M, Thakral B, Yohe S, et al. EBV-positive mucocutaneous ulcer in organ transplant recipients: a localized indolent posttransplant lymphoproliferative disorder. Am J Surg Pathol. 2014;38:1522–1529.CrossRefPubMed
Metadata
Title
Raising the Barr: An Unexpected Lesion at Ileal–Cecal Resection
Authors
V. Mitsialis
Y. Wu
B. Gewurz
R. Bleday
L. A. Doyle
R. W. Winter
M. J. Hamilton
Publication date
01-02-2019
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 2/2019
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-018-5410-z

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