Top

Published in:

01-11-2018 | UNM CLINICAL CASE CONFERENCES

Duodenitis, Diarrhea, and Death in a Patient with AIDS

Authors: Anas Gremida, Davika Kapuria, Marissa A. Tafoya, Archana Kaza, Denis McCarthy

Published in: Digestive Diseases and Sciences | Issue 11/2018

Excerpt

A 47-year-old Native American male was initially evaluated in the emergency room with a 4-month history of diarrhea, which was described as voluminous, foul smelling, and occurring 3–6 times daily, both day and night. It was associated with diminished oral intake, lassitude, anorexia, and an unintentional weight loss of 42 lb over the past year. His roommate additionally reported that, following the diagnosis of infection with human immunodeficiency virus (HIV), the patient had become disoriented, forgetful, and anhedonic. …

Knox TA, Spiegelman D, Skinner SC, Gorbach S. Diarrhea and abnormalities of gastrointestinal function in a cohort of men and women with HIV infection. Am J Gastroenterol. 2000;95:3482–3489.CrossRef

Horsburgh CR Jr. Mycobacterium avium complex infection in the acquired immunodeficiency syndrome. N Engl J Med. 1991;324:1332–1338.CrossRef

Wilcox CM, Schwartz DA, Costonis G, Thompson SE. Chronic unexplained diarrhea in human immunodeficiency virus infection: determination of the best diagnostic approach. Gastroenterology. 1996;110:30–37.CrossRef

Havlik JA, Horsburgh CR, Metchock B, Williams PP, et al. Disseminated Mycobacterium avium complex infection: clinical identification and epidemiologic trends. J Infect Dis. 1992;165:577–580.CrossRef

Horsburgh CR, Chin DP, Yajko DM, Hopewell PC, et al. Environmental risk factors for acquisition of Mycobacterium avium complex in persons with human immunodeficiency virus infection. J Infect Dis. 1994;170:362–367.CrossRef

Chaisson RE, Moore RD, Richman DD, Keruly J, et al. Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine, The Zidovudine Epidemiology Study Group. Am Rev Respir Dis. 1992;146:285–289.CrossRef

Horsburgh CR Jr. The pathophysiology of disseminated Mycobacterium avium complex disease in AIDS. J Infect Dis. 1999;179:461–465.CrossRef

Sun HY, Chen MY, Wu MS, Hsieh SM, et al. Endoscopic appearance of GI mycobacteriosis caused by the Mycobacterium avium complex in a patient with AIDS: case report and review. Gastrointest Endosc. 2005;61:775–779.CrossRef

Connolly GM, Shanson D, Hawkins DA, Webster JN, et al. Non-cryptosporidial diarrhoea in human immunodeficiency virus (HIV) infected patients. Gut. 1989;30:195–200.CrossRef

10.

Cappell MS, Hassan T, Rosenthal S, Mascarenhas M. Gastrointestinal obstruction due to Mycobacterium avium intracellulare associated with the acquired immunodeficiency syndrome. Am J Gastroenterol. 1992;87:1823–1827.PubMed

11.

Gillin JS, Urmacher C, West R, Shike M. Disseminated Mycobacterium avium-intracellulare infection in acquired immunodeficiency syndrome mimicking Whipple’s disease. Gastroenterology. 1983;85:1187–1191.PubMed

12.

Bosch O, Porres JC, Martinez Quesada G, Oliva H, et al. Endoscopic appearance of a duodenal infection by Mycobacterium avium-intracellulare in AIDS. Endoscopy. 1994;26:506.CrossRef

13.

Cappell MS, Philogene C. The endoscopic appearance of severe intestinal Mycobacterium avium complex infection as a coarsely granular mucosa due to massive infiltration and expansion of intestinal villi without mucosal exudation. J Clin Gastroenterol. 1995;21:323–326.CrossRef

14.

Gray JR, Rabeneck L. Atypical mycobacterial infection of the gastrointestinal tract in AIDS patients. Am J Gastroenterol. 1989;84:1521–1524.PubMed

15.

Schneebaum CW, Novick DM, Chabon AB, Strutynsky N, et al. Terminal ileitis associated with Mycobacterium avium intracellulare infection in a homosexual man with acquired immune deficiency syndrome. Gastroenterology. 1987;92:1127–1132.CrossRef

16.

Strom RL, Gruninger RP. AIDS with Mycobacterium avium-intracellulare lesions resembling those of Whipple’s disease. N Engl J Med. 1983;309:1323–1324.CrossRef

17.

Roth RI, Owen RL, Keren DF, Volberding PA. Intestinal infection with Mycobacterium avium in acquired immune deficiency syndrome (AIDS). Histological and clinical comparison with Whipple’s disease. Dig Dis Sci. 1985;30:497–504. https://doi.org/10.1007/BF02966785.CrossRefPubMed

18.

Günthard HF, Saag MS, Benson CA, Rio C, et al. Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2016 recommendations of the international antiviral society-USA panel. JAMA. 2016;316:191–210.CrossRef

19.

Shafran SD, Singer J, Zarowny DP, Phillips P, et al. A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. N Engl J Med. 1996;335:377–383.CrossRef

Title: Duodenitis, Diarrhea, and Death in a Patient with AIDS
Authors: Anas Gremida
Davika Kapuria
Marissa A. Tafoya
Archana Kaza
Denis McCarthy
Publication date: 01-11-2018
Publisher: Springer US
Published in: Digestive Diseases and Sciences / Issue 11/2018
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-018-5301-3

ACC 2024 Congress Coverage

Heart Failure Video

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Duodenitis, Diarrhea, and Death in a Patient with AIDS

Excerpt

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 11/2018

Disruption of GPR35 Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice

Perianal Extramammary Paget’s Disease: More Than Meets the Eye

β-Blockers Improve Presinusoidal Portal Hypertension

Metformin as an Adjunctive Therapy for Pancreatic Cancer: A Review of the Literature on Its Potential Therapeutic Use

Recirculating Immunocompetent Cells in Colitic Mice Intensify Their Lung Response to Bacterial Endotoxin

Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography for Choledocholithiasis in Long-Term Dialysis: A Propensity Score Analysis

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page